BRD-A12633378_Bicyclo[2.2.1]heptane-2-carboxylic acid (2,4,6-trimethyl-phenyl)-amide VU0448090-1_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-A12633378_Bicyclo[2.2.1]heptane-2-carboxylic acid (2,4,6-trimethyl-phenyl)-amide VU0448090-1_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACKR3 atypical chemokine receptor 3
ALB albumin
BACE2 beta-site APP-cleaving enzyme 2
BEX4 brain expressed, X-linked 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CKB creatine kinase, brain
CYR61 cysteine-rich, angiogenic inducer, 61
EDNRA endothelin receptor type A
EXT1 exostosin glycosyltransferase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR2 fibroblast growth factor receptor 2
GAGE3 G antigen 3
GBP1 guanylate binding protein 1, interferon-inducible
HIST1H1C histone cluster 1, H1c
HK2 hexokinase 2
HOXD1 homeobox D1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
JCHAIN joining chain of multimeric IgA and IgM
LAP3 leucine aminopeptidase 3
MBNL2 muscleblind-like splicing regulator 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
NLRP2 NLR family, pyrin domain containing 2
NXN nucleoredoxin
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAPD7 PAP associated domain containing 7
PCDH7 protocadherin 7
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PGK1 phosphoglycerate kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RTN2 reticulon 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOCS2 suppressor of cytokine signaling 2
SST somatostatin
THBS1 thrombospondin 1
TNNT1 troponin T type 1 (skeletal, slow)
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ALCAM activated leukocyte cell adhesion molecule
BUB3 BUB3 mitotic checkpoint protein
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHPT1 choline phosphotransferase 1
CRELD2 cysteine-rich with EGF-like domains 2
CSTA cystatin A (stefin A)
GPX3 glutathione peroxidase 3
H1F0 H1 histone family, member 0
HOXC6 homeobox C6
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRF1 perforin 1 (pore forming protein)
PTX3 pentraxin 3, long
S100A11 S100 calcium binding protein A11
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFRP1 secreted frizzled-related protein 1
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP3 TIMP metallopeptidase inhibitor 3
TM9SF3 transmembrane 9 superfamily member 3
TRIOBP TRIO and F-actin binding protein
TUBB2A tubulin, beta 2A class IIa
ZDHHC6 zinc finger, DHHC-type containing 6