BRD-A12633378_Bicyclo[2.2.1]heptane-2-carboxylic acid (2,4,6-trimethyl-phenyl)-amide VU0448090-1_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-A12633378_Bicyclo[2.2.1]heptane-2-carboxylic acid (2,4,6-trimethyl-phenyl)-amide VU0448090-1_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
AQP3 aquaporin 3 (Gill blood group)
AUTS2 autism susceptibility candidate 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1ORF106 chromosome 1 open reading frame 106
CALML5 calmodulin-like 5
CCL4 chemokine (C-C motif) ligand 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
EGLN3 egl-9 family hypoxia-inducible factor 3
FAM127A family with sequence similarity 127, member A
GPI glucose-6-phosphate isomerase
GPM6B glycoprotein M6B
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JUN jun proto-oncogene
KLF5 Kruppel-like factor 5 (intestinal)
KRT1 keratin 1, type II
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
RALGDS ral guanine nucleotide dissociation stimulator
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
STX1A syntaxin 1A (brain)
TMEM45A transmembrane protein 45A
TPBG trophoblast glycoprotein
TUBB2A tubulin, beta 2A class IIa
VEGFA vascular endothelial growth factor A
WSB1 WD repeat and SOCS box containing 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
CD200 CD200 molecule
DKK1 dickkopf WNT signaling pathway inhibitor 1
KANK1 KN motif and ankyrin repeat domains 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
MID1 midline 1
NQO1 NAD(P)H dehydrogenase, quinone 1
RBP1 retinol binding protein 1, cellular
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SQRDL sulfide quinone reductase-like (yeast)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1