BRD-A12409803_-666_A375_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-A12409803_-666_A375_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ARG2 arginase 2
ATF3 activating transcription factor 3
CA2 carbonic anhydrase II
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CXCR4 chemokine (C-X-C motif) receptor 4
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FABP4 fatty acid binding protein 4, adipocyte
FOLR1 folate receptor 1 (adult)
H2AFV H2A histone family, member V
HIST1H2BD histone cluster 1, H2bd
MEST mesoderm specific transcript
ORC1 origin recognition complex, subunit 1
PEG10 paternally expressed 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRUNE2 prune homolog 2 (Drosophila)
PSPH phosphoserine phosphatase
RBP1 retinol binding protein 1, cellular
RGCC regulator of cell cycle
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCGB1D2 secretoglobin, family 1D, member 2
SFRP4 secreted frizzled-related protein 4
SLC38A2 solute carrier family 38, member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
WASF1 WAS protein family, member 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
CDC45 cell division cycle 45
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IGFBP7 insulin-like growth factor binding protein 7
INHBA inhibin, beta A
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JADE2 jade family PHD finger 2
KLF2 Kruppel-like factor 2
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
LAMC2 laminin, gamma 2
LEF1 lymphoid enhancer-binding factor 1
MOK MOK protein kinase
PI3 peptidase inhibitor 3, skin-derived
PTBP3 polypyrimidine tract binding protein 3
PTX3 pentraxin 3, long
RPS11 ribosomal protein S11
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
SFN stratifin
STX1A syntaxin 1A (brain)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPM1 tropomyosin 1 (alpha)
TSPAN8 tetraspanin 8
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1