BRD-A10523515_GSK-429286A_A549_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

15 genes differentially expressed following the BRD-A10523515_GSK-429286A_A549_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
FXYD3 FXYD domain containing ion transport regulator 3
HSPB8 heat shock 22kDa protein 8
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEF2C myocyte enhancer factor 2C
PDE8B phosphodiesterase 8B
RAP1GAP RAP1 GTPase activating protein
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD24 CD24 molecule
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
TPM1 tropomyosin 1 (alpha)