BRD-A06929388_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

99 genes differentially expressed following the BRD-A06929388_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AMIGO2 adhesion molecule with Ig-like domain 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BCL6 B-cell CLL/lymphoma 6
CBS cystathionine-beta-synthase
CHIC2 cysteine-rich hydrophobic domain 2
CTSZ cathepsin Z
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
DST dystonin
DUSP1 dual specificity phosphatase 1
FOSL1 FOS-like antigen 1
FOXO4 forkhead box O4
FST follistatin
G6PD glucose-6-phosphate dehydrogenase
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFRD1 interferon-related developmental regulator 1
IGF1R insulin-like growth factor 1 receptor
INHBE inhibin, beta E
KLF4 Kruppel-like factor 4 (gut)
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LIMCH1 LIM and calponin homology domains 1
LRP10 low density lipoprotein receptor-related protein 10
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PKP1 plakophilin 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTN pleiotrophin
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RND3 Rho family GTPase 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERTAD2 SERTA domain containing 2
SFN stratifin
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR3 small proline-rich protein 3
TNIP1 TNFAIP3 interacting protein 1
TP63 tumor protein p63
TRIB1 tribbles pseudokinase 1
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP6NL USP6 N-terminal like
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
BASP1 brain abundant, membrane attached signal protein 1
BCLAF1 BCL2-associated transcription factor 1
CALD1 caldesmon 1
CALU calumenin
CCNF cyclin F
CFB complement factor B
CLIC4 chloride intracellular channel 4
CTSH cathepsin H
CXCL12 chemokine (C-X-C motif) ligand 12
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GJA1 gap junction protein, alpha 1, 43kDa
HBB hemoglobin, beta
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KANK2 KN motif and ankyrin repeat domains 2
LAMB1 laminin, beta 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MECOM MDS1 and EVI1 complex locus
MEIS1 Meis homeobox 1
MMP9 matrix metallopeptidase 9
NPY neuropeptide Y
NR2F2 nuclear receptor subfamily 2, group F, member 2
PCP4 Purkinje cell protein 4
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
REEP1 receptor accessory protein 1
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
SCARB2 scavenger receptor class B, member 2
SCG2 secretogranin II
SDC2 syndecan 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC44A4 solute carrier family 44, member 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)