BRD-A06641369_(3-isopropoxyphenyl){1-[(1-isopropyl-1H-pyrazol-4-yl)methyl]piperidin-3-yl}methanone_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-A06641369_(3-isopropoxyphenyl){1-[(1-isopropyl-1H-pyrazol-4-yl)methyl]piperidin-3-yl}methanone_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRF5 adhesion G protein-coupled receptor F5
ADGRL4 adhesion G protein-coupled receptor L4
AURKB aurora kinase B
BEX4 brain expressed, X-linked 4
BGN biglycan
C7 complement component 7
CAST calpastatin
CD93 CD93 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLCA4 chloride channel accessory 4
COL3A1 collagen, type III, alpha 1
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FRZB frizzled-related protein
GAL galanin/GMAP prepropeptide
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
INHBB inhibin, beta B
JCHAIN joining chain of multimeric IgA and IgM
MFAP4 microfibrillar-associated protein 4
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG3 paternally expressed 3
PTPRK protein tyrosine phosphatase, receptor type, K
RGS5 regulator of G-protein signaling 5
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SPARCL1 SPARC-like 1 (hevin)
TCF4 transcription factor 4
TCTN1 tectonic family member 1

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BST2 bone marrow stromal cell antigen 2
CCDC92 coiled-coil domain containing 92
CEMIP cell migration inducing protein, hyaluronan binding
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
MEGF9 multiple EGF-like-domains 9
NQO1 NAD(P)H dehydrogenase, quinone 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMAD6 SMAD family member 6
ZBTB18 zinc finger and BTB domain containing 18
ZMAT3 zinc finger, matrin-type 3