BFTC-909 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma, transitional cell (Cell Line Ontology, CLO_0001949)
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Genes

267 genes with high or low expression in BFTC-909 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
NFYA nuclear transcription factor Y, alpha 3.57806
CPSF3L cleavage and polyadenylation specific factor 3-like 3.52104
DVL1 dishevelled segment polarity protein 1 3.41266
FRS3 fibroblast growth factor receptor substrate 3 3.33726
TFEB transcription factor EB 3.08893
LRP12 low density lipoprotein receptor-related protein 12 3.00775
MOCS1 molybdenum cofactor synthesis 1 2.58784
BYSL bystin-like 2.568
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.52349
CDK11B cyclin-dependent kinase 11B 2.40701
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 2.33068
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 2.32319
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 2.3057
MRPS10 mitochondrial ribosomal protein S10 2.29834
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.29755
DFNA5 deafness, autosomal dominant 5 2.27461
INHBA inhibin, beta A 2.24393
HK1 hexokinase 1 2.22047
DERL1 derlin 1 2.20965
TBC1D2 TBC1 domain family, member 2 2.19203
KIAA0020 KIAA0020 2.18559
ERCC2 excision repair cross-complementation group 2 2.18013
SIN3B SIN3 transcription regulator family member B 2.1733
PDZD7 PDZ domain containing 7 2.16772
LIPC lipase, hepatic 2.15053
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.1362
LAPTM4A lysosomal protein transmembrane 4 alpha 2.1253
RGS3 regulator of G-protein signaling 3 2.11921
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 2.10891
TIMP4 TIMP metallopeptidase inhibitor 4 2.05611
DENND2A DENN/MADD domain containing 2A 2.01154
REM1 RAS (RAD and GEM)-like GTP-binding 1 1.99235
NPR1 natriuretic peptide receptor 1 1.98672
COLGALT1 collagen beta(1-O)galactosyltransferase 1 1.98643
ATAD3A ATPase family, AAA domain containing 3A 1.97768
HHIPL2 HHIP-like 2 1.976
SLAMF8 SLAM family member 8 1.96919
CDC34 cell division cycle 34 1.96858
RNF216 ring finger protein 216 1.94729
ABI3BP ABI family, member 3 (NESH) binding protein 1.92609
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 1.90025
GLTSCR1L GLTSCR1-like 1.89142
HEMK1 HemK methyltransferase family member 1 1.88215
ADAM17 ADAM metallopeptidase domain 17 1.88013
SDF4 stromal cell derived factor 4 1.87185
THY1 Thy-1 cell surface antigen 1.86234
COL9A2 collagen, type IX, alpha 2 1.85858
TWF2 twinfilin actin binding protein 2 1.85831
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.83222
UPP1 uridine phosphorylase 1 1.82952
TLL2 tolloid-like 2 1.81154
NID2 nidogen 2 (osteonidogen) 1.80252
STOML1 stomatin (EPB72)-like 1 1.78084
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 1.78068
NADK NAD kinase 1.77536
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.76608
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 1.74114
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.74088
SPON2 spondin 2, extracellular matrix protein 1.73175
COL5A3 collagen, type V, alpha 3 1.72519
RXFP3 relaxin/insulin-like family peptide receptor 3 1.72044
LMNB2 lamin B2 1.71466
DDIT4 DNA-damage-inducible transcript 4 1.71224
TCHH trichohyalin 1.70601
RASIP1 Ras interacting protein 1 1.70333
COL6A2 collagen, type VI, alpha 2 1.70178
EFCAB1 EF-hand calcium binding domain 1 1.69633
PTGIS prostaglandin I2 (prostacyclin) synthase 1.69571
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.68579
BAALC brain and acute leukemia, cytoplasmic 1.68555
ANO10 anoctamin 10 1.68464
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.67531
ZNF282 zinc finger protein 282 1.67186
RAB2A RAB2A, member RAS oncogene family 1.66968
WNT2B wingless-type MMTV integration site family, member 2B 1.66859
KRT35 keratin 35, type I 1.66585
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.65265
INHBE inhibin, beta E 1.65163
ARHGAP1 Rho GTPase activating protein 1 1.64202
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.63914
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 1.63512
TGFB1I1 transforming growth factor beta 1 induced transcript 1 1.63466
ASCC1 activating signal cointegrator 1 complex subunit 1 1.62759
CCSER2 coiled-coil serine-rich protein 2 1.62208
CD14 CD14 molecule 1.62016
LRRC8E leucine rich repeat containing 8 family, member E 1.61611
RABAC1 Rab acceptor 1 (prenylated) 1.60748
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 1.60533
CCL11 chemokine (C-C motif) ligand 11 1.60503
SLC12A8 solute carrier family 12, member 8 1.60464
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.60275
GMPPA GDP-mannose pyrophosphorylase A 1.60215
HOMER3 homer scaffolding protein 3 1.60149
LSP1 lymphocyte-specific protein 1 1.60028
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 1.59927
WNT5B wingless-type MMTV integration site family, member 5B 1.58966
MED16 mediator complex subunit 16 1.58828
COL6A1 collagen, type VI, alpha 1 1.58123
MAP4 microtubule-associated protein 4 1.57745
HRH1 histamine receptor H1 1.57707
NOSIP nitric oxide synthase interacting protein 1.57487
BTBD2 BTB (POZ) domain containing 2 1.56978
STK11 serine/threonine kinase 11 1.5694
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 1.56446
POLRMT polymerase (RNA) mitochondrial (DNA directed) 1.55513
AMPD2 adenosine monophosphate deaminase 2 1.55345
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 1.55313
MSC musculin 1.55181
SIGLEC15 sialic acid binding Ig-like lectin 15 1.55053
SEC11A SEC11 homolog A (S. cerevisiae) 1.54936
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.54658
LPP LIM domain containing preferred translocation partner in lipoma 1.5453
CTSL cathepsin L 1.54056
DEFA6 defensin, alpha 6, Paneth cell-specific 1.53633
ELANE elastase, neutrophil expressed 1.5316
RCL1 RNA terminal phosphate cyclase-like 1 1.52603
FAT2 FAT atypical cadherin 2 1.52057
TLN2 talin 2 1.51873
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.5179
APH1B APH1B gamma secretase subunit 1.51624
TKT transketolase 1.51305
EHD4 EH-domain containing 4 1.49604
HOMER2 homer scaffolding protein 2 1.4897
AZU1 azurocidin 1 1.48059
FAM65A family with sequence similarity 65, member A 1.47637
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.47432
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 1.46949
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 1.46843
TNIP3 TNFAIP3 interacting protein 3 1.45053
RRAS related RAS viral (r-ras) oncogene homolog 1.45003
ZFP36L1 ZFP36 ring finger protein-like 1 1.44905
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1.44768
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 1.44713
NME6 NME/NM23 nucleoside diphosphate kinase 6 1.44392
F2RL2 coagulation factor II (thrombin) receptor-like 2 1.44177
SND1 staphylococcal nuclease and tudor domain containing 1 1.44061
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 1.43885
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 1.43284
JADE2 jade family PHD finger 2 1.41991
BDKRB1 bradykinin receptor B1 1.41919
ELL elongation factor RNA polymerase II 1.41892
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 1.41856
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 1.41727

low expression

Symbol Name Standardized Value
ATRX alpha thalassemia/mental retardation syndrome X-linked -3.53725
LLGL2 lethal giant larvae homolog 2 (Drosophila) -3.49301
MED17 mediator complex subunit 17 -3.087
ADRBK1 adrenergic, beta, receptor kinase 1 -2.94107
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.71561
VAV3 vav 3 guanine nucleotide exchange factor -2.71192
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.70352
YEATS4 YEATS domain containing 4 -2.52146
CLCA1 chloride channel accessory 1 -2.42347
CCNG2 cyclin G2 -2.2434
FANCF Fanconi anemia, complementation group F -2.22702
TKFC triokinase/FMN cyclase -2.18252
ZNF195 zinc finger protein 195 -2.12824
GTF2B general transcription factor IIB -2.09978
PSME4 proteasome (prosome, macropain) activator subunit 4 -2.09363
PRPF4B pre-mRNA processing factor 4B -2.02946
RAN RAN, member RAS oncogene family -2.02001
API5 apoptosis inhibitor 5 -2.01988
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 -1.98936
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.97873
CAT catalase -1.97597
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.96068
GLE1 GLE1 RNA export mediator -1.95757
POLI polymerase (DNA directed) iota -1.95244
ZBTB44 zinc finger and BTB domain containing 44 -1.94704
DLAT dihydrolipoamide S-acetyltransferase -1.94456
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.9347
DBR1 debranching RNA lariats 1 -1.91199
H3F3A H3 histone, family 3A -1.90849
SNRPE small nuclear ribonucleoprotein polypeptide E -1.89371
FIP1L1 factor interacting with PAPOLA and CPSF1 -1.88585
HIST2H2BE histone cluster 2, H2be -1.87388
RORA RAR-related orphan receptor A -1.86563
STAMBP STAM binding protein -1.86224
PDHX pyruvate dehydrogenase complex, component X -1.85419
YOD1 YOD1 deubiquitinase -1.84929
AZGP1 alpha-2-glycoprotein 1, zinc-binding -1.84777
KCTD20 potassium channel tetramerization domain containing 20 -1.83914
UBE4A ubiquitination factor E4A -1.83702
PTRH2 peptidyl-tRNA hydrolase 2 -1.82892
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -1.8284
SF3B3 splicing factor 3b, subunit 3, 130kDa -1.81213
IFNA10 interferon, alpha 10 -1.80087
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 -1.79331
KDM4A lysine (K)-specific demethylase 4A -1.78567
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 -1.77513
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -1.76737
FRG1 FSHD region gene 1 -1.76605
MRFAP1L1 Morf4 family associated protein 1-like 1 -1.75293
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.7476
HIPK3 homeodomain interacting protein kinase 3 -1.73559
MRPS22 mitochondrial ribosomal protein S22 -1.7229
FTSJ3 FtsJ homolog 3 (E. coli) -1.69219
THOC1 THO complex 1 -1.69216
IMMT inner membrane protein, mitochondrial -1.68832
SNIP1 Smad nuclear interacting protein 1 -1.68625
KAT5 K(lysine) acetyltransferase 5 -1.68481
LOC642236 FSHD region gene 1 pseudogene -1.66911
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -1.66772
KIAA0894 KIAA0894 protein -1.6509
KLHL26 kelch-like family member 26 -1.64996
SRSF8 serine/arginine-rich splicing factor 8 -1.64994
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -1.64271
CNTNAP2 contactin associated protein-like 2 -1.64256
PCDHA5 protocadherin alpha 5 -1.64142
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -1.64023
ANKRD17 ankyrin repeat domain 17 -1.63133
LPPR2 lipid phosphate phosphatase-related protein type 2 -1.6294
PDZRN3 PDZ domain containing ring finger 3 -1.62898
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -1.62704
PCBP1 poly(rC) binding protein 1 -1.6222
SLC16A6 solute carrier family 16, member 6 -1.6156
DAPK3 death-associated protein kinase 3 -1.61212
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -1.60659
TMEM135 transmembrane protein 135 -1.5947
TAC1 tachykinin, precursor 1 -1.57851
EPC1 enhancer of polycomb homolog 1 (Drosophila) -1.5773
KDM3A lysine (K)-specific demethylase 3A -1.57705
CHKA choline kinase alpha -1.57587
CDC73 cell division cycle 73 -1.57258
SYNJ1 synaptojanin 1 -1.56959
GJA10 gap junction protein, alpha 10, 62kDa -1.56932
LSR lipolysis stimulated lipoprotein receptor -1.56901
HIST1H3D histone cluster 1, H3d -1.5606
TMPRSS11D transmembrane protease, serine 11D -1.55719
TMEM126B transmembrane protein 126B -1.54511
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -1.54206
VTI1B vesicle transport through interaction with t-SNAREs 1B -1.53585
PDCD6 programmed cell death 6 -1.53375
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -1.53227
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.52018
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -1.51963
PPP5C protein phosphatase 5, catalytic subunit -1.51629
ACOX1 acyl-CoA oxidase 1, palmitoyl -1.51335
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -1.5029
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -1.49719
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -1.49221
PGPEP1 pyroglutamyl-peptidase I -1.48886
ZNF322P1 zinc finger protein 322 pseudogene 1 -1.48863
ANO2 anoctamin 2, calcium activated chloride channel -1.48221
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -1.48199
JUP junction plakoglobin -1.48045
FBXO2 F-box protein 2 -1.48033
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.46759
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 -1.46557
PRCC papillary renal cell carcinoma (translocation-associated) -1.46449
CFI complement factor I -1.46334
TUBA4B tubulin, alpha 4b -1.45062
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -1.44931
FGL2 fibrinogen-like 2 -1.4487
UBE3A ubiquitin protein ligase E3A -1.44855
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -1.44575
HIST1H2BH histone cluster 1, H2bh -1.44564
NASP nuclear autoantigenic sperm protein (histone-binding) -1.44449
ZBTB40 zinc finger and BTB domain containing 40 -1.44262
GCAT glycine C-acetyltransferase -1.44153
CD160 CD160 molecule -1.4398
TLR1 toll-like receptor 1 -1.43833
GRAMD1C GRAM domain containing 1C -1.4374
TBX10 T-box 10 -1.43689
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -1.43138
ZNF143 zinc finger protein 143 -1.42735
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -1.41833
ZNF266 zinc finger protein 266 -1.41606