BCB000040-7559 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the BCB000040-7559 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKRD6 ankyrin repeat domain 6
APP amyloid beta (A4) precursor protein
ARHGAP19 Rho GTPase activating protein 19
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
AXL AXL receptor tyrosine kinase
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
BNC2 basonuclin 2
BRAP BRCA1 associated protein
C9ORF114 chromosome 9 open reading frame 114
CALD1 caldesmon 1
CCNT1 cyclin T1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CLCC1 chloride channel CLIC-like 1
CLCN3 chloride channel, voltage-sensitive 3
CLDN3 claudin 3
COL6A1 collagen, type VI, alpha 1
DCAF13 DDB1 and CUL4 associated factor 13
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DND1 DND microRNA-mediated repression inhibitor 1
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
E2F3 E2F transcription factor 3
EFCAB2 EF-hand calcium binding domain 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELP3 elongator acetyltransferase complex subunit 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHA1 EPH receptor A1
FADS3 fatty acid desaturase 3
FAM20B family with sequence similarity 20, member B
FBXO42 F-box protein 42
GABARAPL1 GABA(A) receptor-associated protein like 1
GOSR2 golgi SNAP receptor complex member 2
HIST1H1E histone cluster 1, H1e
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
HMOX1 heme oxygenase 1
HNF1B HNF1 homeobox B
HNRNPL heterogeneous nuclear ribonucleoprotein L
IFI35 interferon-induced protein 35
IGFLR1 IGF-like family receptor 1
IL27RA interleukin 27 receptor, alpha
IL6ST interleukin 6 signal transducer
KDM6B lysine (K)-specific demethylase 6B
KIAA0930 KIAA0930
KIAA1462 KIAA1462
KISS1 KiSS-1 metastasis-suppressor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRP5L low density lipoprotein receptor-related protein 5-like
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MRPS11 mitochondrial ribosomal protein S11
NPEPL1 aminopeptidase-like 1
NUMB numb homolog (Drosophila)
OGG1 8-oxoguanine DNA glycosylase
PANK3 pantothenate kinase 3
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PER1 period circadian clock 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLCE1 phospholipase C, epsilon 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLXNB3 plexin B3
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPARD peroxisome proliferator-activated receptor delta
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRSS8 protease, serine, 8
QKI QKI, KH domain containing, RNA binding
RNF126P1 ring finger protein 126 pseudogene 1
RPL13 ribosomal protein L13
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS9 ribosomal protein S9
RTN2 reticulon 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC2 structural maintenance of chromosomes 2
SOWAHC sosondowah ankyrin repeat domain family member C
SREBF2 sterol regulatory element binding transcription factor 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK11 serine/threonine kinase 11
STK19 serine/threonine kinase 19
STX5 syntaxin 5
TAGLN3 transgelin 3
TEAD3 TEA domain family member 3
THBS3 thrombospondin 3
TMEM132A transmembrane protein 132A
TMPO thymopoietin
TNK1 tyrosine kinase, non-receptor, 1
TRAK1 trafficking protein, kinesin binding 1
TRAPPC6A trafficking protein particle complex 6A
TRIM2 tripartite motif containing 2
TTBK2 tau tubulin kinase 2
TTC38 tetratricopeptide repeat domain 38
XYLT2 xylosyltransferase II
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARPIN actin-related protein 2/3 complex inhibitor
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCL9 B-cell CLL/lymphoma 9
C1R complement component 1, r subcomponent
CARD8 caspase recruitment domain family, member 8
CASD1 CAS1 domain containing 1
CBS cystathionine-beta-synthase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD53 CD53 molecule
CDHR2 cadherin-related family member 2
CEMIP cell migration inducing protein, hyaluronan binding
CENPJ centromere protein J
CFAP69 cilia and flagella associated protein 69
CHML choroideremia-like (Rab escort protein 2)
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCN6 chloride channel, voltage-sensitive 6
CLEC16A C-type lectin domain family 16, member A
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYZ crystallin, zeta (quinone reductase)
CST4 cystatin S
DAGLA diacylglycerol lipase, alpha
DDN dendrin
DNAH7 dynein, axonemal, heavy chain 7
EDIL3 EGF-like repeats and discoidin I-like domains 3
EXD3 exonuclease 3'-5' domain containing 3
EXOSC1 exosome component 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM118A family with sequence similarity 118, member A
FBXL15 F-box and leucine-rich repeat protein 15
GLS2 glutaminase 2 (liver, mitochondrial)
GLT8D2 glycosyltransferase 8 domain containing 2
GPATCH2L G patch domain containing 2-like
GUSBP3 glucuronidase, beta pseudogene 3
H1F0 H1 histone family, member 0
HACD1 3-hydroxyacyl-CoA dehydratase 1
HP1BP3 heterochromatin protein 1, binding protein 3
HYI hydroxypyruvate isomerase (putative)
IFT81 intraflagellar transport 81
IL17RA interleukin 17 receptor A
INSIG2 insulin induced gene 2
ITFG1 integrin alpha FG-GAP repeat containing 1
JAM3 junctional adhesion molecule 3
KIAA0355 KIAA0355
KLF2 Kruppel-like factor 2
LHFP lipoma HMGIC fusion partner
LIMS2 LIM and senescent cell antigen-like domains 2
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
MAGEF1 melanoma antigen family F1
MAMLD1 mastermind-like domain containing 1
MANEA mannosidase, endo-alpha
MAPK12 mitogen-activated protein kinase 12
MBTD1 mbt domain containing 1
MCM9 minichromosome maintenance complex component 9
MLYCD malonyl-CoA decarboxylase
MMRN2 multimerin 2
MOXD1 monooxygenase, DBH-like 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PCOLCE procollagen C-endopeptidase enhancer
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PSKH1 protein serine kinase H1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABL6 RAB, member RAS oncogene family-like 6
RARS arginyl-tRNA synthetase
RHBDD3 rhomboid domain containing 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF39 ring finger protein 39
SCIN scinderin
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC16A6 solute carrier family 16, member 6
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
ZFP36 ZFP36 ring finger protein
ZNF35 zinc finger protein 35
ZNF443 zinc finger protein 443
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF816 zinc finger protein 816