BCB000040-7493 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the BCB000040-7493 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADCK2 aarF domain containing kinase 2
ADGRL2 adhesion G protein-coupled receptor L2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATF5 activating transcription factor 5
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
C14ORF79 chromosome 14 open reading frame 79
C1S complement component 1, s subcomponent
C6ORF47 chromosome 6 open reading frame 47
C9ORF156 chromosome 9 open reading frame 156
CA9 carbonic anhydrase IX
CALD1 caldesmon 1
CD247 CD247 molecule
CDH8 cadherin 8, type 2
CDK10 cyclin-dependent kinase 10
CENPO centromere protein O
CLEC11A C-type lectin domain family 11, member A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNR2 cannabinoid receptor 2 (macrophage)
CNTNAP1 contactin associated protein 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CORO2A coronin, actin binding protein, 2A
CUL9 cullin 9
EML2 echinoderm microtubule associated protein like 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPHB2 EPH receptor B2
EXOSC2 exosome component 2
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FAT4 FAT atypical cadherin 4
FEM1B fem-1 homolog b (C. elegans)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GLS2 glutaminase 2 (liver, mitochondrial)
GPR85 G protein-coupled receptor 85
GRIK5 glutamate receptor, ionotropic, kainate 5
HEMK1 HemK methyltransferase family member 1
HLX H2.0-like homeobox
IFI6 interferon, alpha-inducible protein 6
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IQCG IQ motif containing G
IQCK IQ motif containing K
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB5 integrin, beta 5
KCTD15 potassium channel tetramerization domain containing 15
KCTD17 potassium channel tetramerization domain containing 17
KRT6B keratin 6B, type II
LAMP1 lysosomal-associated membrane protein 1
LRP3 low density lipoprotein receptor-related protein 3
MECOM MDS1 and EVI1 complex locus
MEF2D myocyte enhancer factor 2D
MIIP migration and invasion inhibitory protein
NPY1R neuropeptide Y receptor Y1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PACS1 phosphofurin acidic cluster sorting protein 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDCD6 programmed cell death 6
PDS5B PDS5 cohesin associated factor B
PHF20L1 PHD finger protein 20-like 1
PIGR polymeric immunoglobulin receptor
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKP4 plakophilin 4
PRKCB protein kinase C, beta
RAB35 RAB35, member RAS oncogene family
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL18 ribosomal protein L18
RUNDC3A RUN domain containing 3A
SAFB2 scaffold attachment factor B2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERGEF secretion regulating guanine nucleotide exchange factor
SETDB1 SET domain, bifurcated 1
SFTPB surfactant protein B
SIRT3 sirtuin 3
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STMN1 stathmin 1
STOML1 stomatin (EPB72)-like 1
SUGP1 SURP and G patch domain containing 1
SYNGR1 synaptogyrin 1
SYP synaptophysin
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TBC1D22A TBC1 domain family, member 22A
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM231 transmembrane protein 231
TMEM70 transmembrane protein 70
TNS1 tensin 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TREM1 triggering receptor expressed on myeloid cells 1
TRIO trio Rho guanine nucleotide exchange factor
TUBD1 tubulin, delta 1
ULK2 unc-51 like autophagy activating kinase 2
USP34 ubiquitin specific peptidase 34
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
ZHX3 zinc fingers and homeoboxes 3
ZNF428 zinc finger protein 428
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM15 ADAM metallopeptidase domain 15
ADGRB2 adhesion G protein-coupled receptor B2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARPIN actin-related protein 2/3 complex inhibitor
ARRB1 arrestin, beta 1
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
ATG10 autophagy related 10
ATG2B autophagy related 2B
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEX4 brain expressed, X-linked 4
BMP4 bone morphogenetic protein 4
BNC2 basonuclin 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C22ORF46 chromosome 22 open reading frame 46
C4ORF19 chromosome 4 open reading frame 19
CD70 CD70 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CNTD2 cyclin N-terminal domain containing 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF13 DDB1 and CUL4 associated factor 13
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP13 dual specificity phosphatase 13
EIF5A2 eukaryotic translation initiation factor 5A2
ERAP2 endoplasmic reticulum aminopeptidase 2
ETV6 ets variant 6
FAM188A family with sequence similarity 188, member A
FAM50B family with sequence similarity 50, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FMO4 flavin containing monooxygenase 4
FZD7 frizzled class receptor 7
GAREM GRB2 associated, regulator of MAPK1
GMIP GEM interacting protein
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HHLA1 HERV-H LTR-associating 1
HLA-DMB major histocompatibility complex, class II, DM beta
IQCC IQ motif containing C
IRAK4 interleukin-1 receptor-associated kinase 4
KIAA0355 KIAA0355
KIAA1549L KIAA1549-like
KLHL12 kelch-like family member 12
LGALS4 lectin, galactoside-binding, soluble, 4
LIPG lipase, endothelial
LRRK1 leucine-rich repeat kinase 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MILR1 mast cell immunoglobulin-like receptor 1
MPDU1 mannose-P-dolichol utilization defect 1
MXD3 MAX dimerization protein 3
NABP1 nucleic acid binding protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
PARM1 prostate androgen-regulated mucin-like protein 1
PDGFRL platelet-derived growth factor receptor-like
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGPEP1 pyroglutamyl-peptidase I
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POM121 POM121 transmembrane nucleoporin
RAB23 RAB23, member RAS oncogene family
RAI2 retinoic acid induced 2
SCRG1 stimulator of chondrogenesis 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC25A40 solute carrier family 25, member 40
SLC41A3 solute carrier family 41, member 3
SNRPN small nuclear ribonucleoprotein polypeptide N
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAC SH3 and cysteine rich domain
SYTL2 synaptotagmin-like 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
THBS3 thrombospondin 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMC7 transmembrane channel-like 7
TMEM156 transmembrane protein 156
TMEM183A transmembrane protein 183A
TMEM57 transmembrane protein 57
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TUBGCP5 tubulin, gamma complex associated protein 5
UEVLD UEV and lactate/malate dehyrogenase domains
ULBP2 UL16 binding protein 2
USP6NL USP6 N-terminal like
WDR33 WD repeat domain 33
WDR62 WD repeat domain 62
ZBTB39 zinc finger and BTB domain containing 39
ZNF227 zinc finger protein 227
ZNF230 zinc finger protein 230
ZNF665 zinc finger protein 665
ZNF667 zinc finger protein 667
ZNF671 zinc finger protein 671
ZNF747 zinc finger protein 747