BCB000040-7488 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the BCB000040-7488 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AEBP1 AE binding protein 1
AGRN agrin
AIM1L absent in melanoma 1-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDOB aldolase B, fructose-bisphosphate
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARMC4 armadillo repeat containing 4
ARSD arylsulfatase D
ATP10B ATPase, class V, type 10B
BTBD7 BTB (POZ) domain containing 7
C1QB complement component 1, q subcomponent, B chain
CABP5 calcium binding protein 5
CAPN10 calpain 10
CCND2 cyclin D2
CD6 CD6 molecule
CHAD chondroadherin
CNTD2 cyclin N-terminal domain containing 2
COL9A3 collagen, type IX, alpha 3
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DCHS1 dachsous cadherin-related 1
DXO decapping exoribonuclease
EPHA2 EPH receptor A2
FAM107A family with sequence similarity 107, member A
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FEM1B fem-1 homolog b (C. elegans)
FLOT1 flotillin 1
FNTB farnesyltransferase, CAAX box, beta
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GFI1 growth factor independent 1 transcription repressor
GGT1 gamma-glutamyltransferase 1
GIF gastric intrinsic factor (vitamin B synthesis)
GPER1 G protein-coupled estrogen receptor 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAP1 huntingtin-associated protein 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXA11 homeobox A11
HP1BP3 heterochromatin protein 1, binding protein 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICOSLG inducible T-cell co-stimulator ligand
IFFO1 intermediate filament family orphan 1
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ING4 inhibitor of growth family, member 4
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM5D lysine (K)-specific demethylase 5D
KRT14 keratin 14, type I
KRT85 keratin 85, type II
LHX6 LIM homeobox 6
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LTBP4 latent transforming growth factor beta binding protein 4
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MCAM melanoma cell adhesion molecule
MMP25 matrix metallopeptidase 25
MVB12B multivesicular body subunit 12B
NCAM1 neural cell adhesion molecule 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NR6A1 nuclear receptor subfamily 6, group A, member 1
OGFR opioid growth factor receptor
PCLO piccolo presynaptic cytomatrix protein
PLEKHO2 pleckstrin homology domain containing, family O member 2
POU2F2 POU class 2 homeobox 2
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RASAL1 RAS protein activator like 1 (GAP1 like)
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SETD8 SET domain containing (lysine methyltransferase) 8
SIX1 SIX homeobox 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMG5 SMG5 nonsense mediated mRNA decay factor
SMG7-AS1 SMG7 antisense RNA 1
SNAP23 synaptosomal-associated protein, 23kDa
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
STAB2 stabilin 2
STMN1 stathmin 1
TCTN1 tectonic family member 1
TK2 thymidine kinase 2, mitochondrial
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM23 tripartite motif containing 23
UBA6 ubiquitin-like modifier activating enzyme 6
UBXN1 UBX domain protein 1
VPREB3 pre-B lymphocyte 3
VSX1 visual system homeobox 1
VWA5A von Willebrand factor A domain containing 5A
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZNF175 zinc finger protein 175
ZNF44 zinc finger protein 44

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACPP acid phosphatase, prostate
ARPIN actin-related protein 2/3 complex inhibitor
ART1 ADP-ribosyltransferase 1
ATAT1 alpha tubulin acetyltransferase 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BARX2 BARX homeobox 2
C10ORF95 chromosome 10 open reading frame 95
C16ORF59 chromosome 16 open reading frame 59
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF46 chromosome 22 open reading frame 46
C5ORF30 chromosome 5 open reading frame 30
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CNTN5 contactin 5
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIXDC1 DIX domain containing 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSE dermatan sulfate epimerase
DTX2 deltex 2, E3 ubiquitin ligase
E2F8 E2F transcription factor 8
EGFL7 EGF-like-domain, multiple 7
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELP6 elongator acetyltransferase complex subunit 6
ENO3 enolase 3 (beta, muscle)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM110B family with sequence similarity 110, member B
FBXO22 F-box protein 22
FILIP1L filamin A interacting protein 1-like
FRK fyn-related Src family tyrosine kinase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRPR gastrin-releasing peptide receptor
HDAC4 histone deacetylase 4
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AJ histone cluster 1, H2aj
HIST2H2AA3 histone cluster 2, H2aa3
HOXA3 homeobox A3
HOXC8 homeobox C8
INO80D INO80 complex subunit D
IRF6 interferon regulatory factor 6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
L2HGDH L-2-hydroxyglutarate dehydrogenase
LINS lines homolog (Drosophila)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
MEGF8 multiple EGF-like-domains 8
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NHLRC2 NHL repeat containing 2
NPY1R neuropeptide Y receptor Y1
NSUN6 NOP2/Sun domain family, member 6
OSGIN1 oxidative stress induced growth inhibitor 1
PADI3 peptidyl arginine deiminase, type III
PDE9A phosphodiesterase 9A
PER3 period circadian clock 3
PIPOX pipecolic acid oxidase
PRPH peripherin
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RASIP1 Ras interacting protein 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCOR3 REST corepressor 3
REEP1 receptor accessory protein 1
RFTN1 raftlin, lipid raft linker 1
RIN1 Ras and Rab interactor 1
RLN1 relaxin 1
RPGRIP1L RPGRIP1-like
SAYSD1 SAYSVFN motif domain containing 1
SH3D21 SH3 domain containing 21
SLC12A8 solute carrier family 12, member 8
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMIM14 small integral membrane protein 14
SNTA1 syntrophin, alpha 1
SYNPO synaptopodin
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TICAM1 toll-like receptor adaptor molecule 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMPRSS4 transmembrane protease, serine 4
TRIM21 tripartite motif containing 21
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VPS9D1 VPS9 domain containing 1
WWC2 WW and C2 domain containing 2
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26