BCB000039-7531 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the BCB000039-7531 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOX15 arachidonate 15-lipoxygenase
ALS2CL ALS2 C-terminal like
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL15 ADP-ribosylation factor-like 15
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF7IP activating transcription factor 7 interacting protein
BBS9 Bardet-Biedl syndrome 9
BCAM basal cell adhesion molecule (Lutheran blood group)
BGLAP bone gamma-carboxyglutamate (gla) protein
C16ORF45 chromosome 16 open reading frame 45
C17ORF80 chromosome 17 open reading frame 80
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CDC14B cell division cycle 14B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC5L cell division cycle 5-like
CDKL3 cyclin-dependent kinase-like 3
CLASP2 cytoplasmic linker associated protein 2
CNOT3 CCR4-NOT transcription complex, subunit 3
CNOT4 CCR4-NOT transcription complex, subunit 4
CSF1R colony stimulating factor 1 receptor
CST6 cystatin E/M
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DEPDC5 DEP domain containing 5
DIAPH2 diaphanous-related formin 2
DNAH3 dynein, axonemal, heavy chain 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUSP6 dual specificity phosphatase 6
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FBXL8 F-box and leucine-rich repeat protein 8
FGD1 FYVE, RhoGEF and PH domain containing 1
FLT4 fms-related tyrosine kinase 4
GJB3 gap junction protein, beta 3, 31kDa
GLDC glycine dehydrogenase (decarboxylating)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HLF hepatic leukemia factor
HNMT histamine N-methyltransferase
HR hair growth associated
ICAM1 intercellular adhesion molecule 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0040 KIAA0040
KRT83 keratin 83, type II
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMP1 lysosomal-associated membrane protein 1
LIMCH1 LIM and calponin homology domains 1
LIMK1 LIM domain kinase 1
LMCD1 LIM and cysteine-rich domains 1
LOC157562 uncharacterized LOC157562
LOC441601 septin 7 pseudogene
MAPT microtubule-associated protein tau
MBD2 methyl-CpG binding domain protein 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MED16 mediator complex subunit 16
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF2 neurofibromin 2 (merlin)
NLE1 notchless homolog 1 (Drosophila)
NRSN2 neurensin 2
NT5C 5', 3'-nucleotidase, cytosolic
NTF3 neurotrophin 3
NUMA1 nuclear mitotic apparatus protein 1
OLFML2A olfactomedin-like 2A
PADI3 peptidyl arginine deiminase, type III
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PORCN porcupine homolog (Drosophila)
PRF1 perforin 1 (pore forming protein)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB27B RAB27B, member RAS oncogene family
RBM5 RNA binding motif protein 5
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RFTN1 raftlin, lipid raft linker 1
RRBP1 ribosome binding protein 1
SAMD4A sterile alpha motif domain containing 4A
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKAP1 src kinase associated phosphoprotein 1
SLC17A2 solute carrier family 17, member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBKBP1 TBK1 binding protein 1
TCF3 transcription factor 3
TLE2 transducin-like enhancer of split 2
TRIM3 tripartite motif containing 3
TTC28 tetratricopeptide repeat domain 28
UNC5B unc-5 homolog B (C. elegans)
WIPI2 WD repeat domain, phosphoinositide interacting 2
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZDHHC17 zinc finger, DHHC-type containing 17

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOH apolipoprotein H (beta-2-glycoprotein I)
BCL6 B-cell CLL/lymphoma 6
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BEX4 brain expressed, X-linked 4
BMP15 bone morphogenetic protein 15
C9ORF9 chromosome 9 open reading frame 9
CASS4 Cas scaffolding protein family member 4
CCL19 chemokine (C-C motif) ligand 19
CD160 CD160 molecule
CDK3 cyclin-dependent kinase 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEL carboxyl ester lipase
CLGN calmegin
CLTCL1 clathrin, heavy chain-like 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CXADR coxsackie virus and adenovirus receptor
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DMTN dematin actin binding protein
EPHA2 EPH receptor A2
EPHB6 EPH receptor B6
FAM110D family with sequence similarity 110, member D
FAM135A family with sequence similarity 135, member A
FAM63A family with sequence similarity 63, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FILIP1L filamin A interacting protein 1-like
FLNC filamin C, gamma
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GATA4 GATA binding protein 4
GBP2 guanylate binding protein 2, interferon-inducible
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GEMIN7 gem (nuclear organelle) associated protein 7
GFI1 growth factor independent 1 transcription repressor
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSPT2 G1 to S phase transition 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HIST1H3E histone cluster 1, H3e
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IFNA21 interferon, alpha 21
IL13 interleukin 13
IL15RA interleukin 15 receptor, alpha
ITPKB inositol-trisphosphate 3-kinase B
JAK2 Janus kinase 2
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCTD17 potassium channel tetramerization domain containing 17
KLF3 Kruppel-like factor 3 (basic)
LIM2 lens intrinsic membrane protein 2, 19kDa
LINC00652 long intergenic non-protein coding RNA 652
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEGF8 multiple EGF-like-domains 8
MTCP1 mature T-cell proliferation 1
MUC3B mucin 3B, cell surface associated
NELL2 NEL-like 2 (chicken)
NXPH3 neurexophilin 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PALM paralemmin
PCDHB6 protocadherin beta 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE9A phosphodiesterase 9A
PDZK1IP1 PDZK1 interacting protein 1
PLG plasminogen
PNPLA2 patatin-like phospholipase domain containing 2
PPT2 palmitoyl-protein thioesterase 2
PRKG2 protein kinase, cGMP-dependent, type II
PRSS2 protease, serine, 2 (trypsin 2)
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBDD3 rhomboid domain containing 3
RNF170 ring finger protein 170
RNF39 ring finger protein 39
RPL3L ribosomal protein L3-like
S100A7 S100 calcium binding protein A7
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SGK1 serum/glucocorticoid regulated kinase 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC25A40 solute carrier family 25, member 40
SPO11 SPO11 meiotic protein covalently bound to DSB
STAB2 stabilin 2
TBC1D2 TBC1 domain family, member 2
TGFBR3 transforming growth factor, beta receptor III
TH tyrosine hydroxylase
TICAM1 toll-like receptor adaptor molecule 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM104 transmembrane protein 104
TMEM8B transmembrane protein 8B
TNNI3 troponin I type 3 (cardiac)
TSC22D4 TSC22 domain family, member 4
TSPAN2 tetraspanin 2
TUBA3D tubulin, alpha 3d
ZKSCAN4 zinc finger with KRAB and SCAN domains 4