BCB000039-7510 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the BCB000039-7510 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AMBRA1 autophagy/beclin-1 regulator 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APC adenomatous polyposis coli
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS10 Bardet-Biedl syndrome 10
BCORL1 BCL6 corepressor-like 1
BDNF brain-derived neurotrophic factor
BMP1 bone morphogenetic protein 1
BRCA2 breast cancer 2, early onset
CAMKMT calmodulin-lysine N-methyltransferase
CDK13 cyclin-dependent kinase 13
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
EPHB2 EPH receptor B2
FAS Fas cell surface death receptor
FLCN folliculin
GPATCH4 G patch domain containing 4
GRIK5 glutamate receptor, ionotropic, kainate 5
HOXA10 homeobox A10
HSPG2 heparan sulfate proteoglycan 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INADL InaD-like (Drosophila)
INHBA inhibin, beta A
IVNS1ABP influenza virus NS1A binding protein
KALRN kalirin, RhoGEF kinase
KIFC3 kinesin family member C3
LINC00094 long intergenic non-protein coding RNA 94
MECP2 methyl CpG binding protein 2
MTMR12 myotubularin related protein 12
MX1 MX dynamin-like GTPase 1
NF2 neurofibromin 2 (merlin)
NRF1 nuclear respiratory factor 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PARP3 poly (ADP-ribose) polymerase family, member 3
PGK1 phosphoglycerate kinase 1
PHF20L1 PHD finger protein 20-like 1
PHF3 PHD finger protein 3
PIGR polymeric immunoglobulin receptor
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PKNOX1 PBX/knotted 1 homeobox 1
PKP1 plakophilin 1
PLAA phospholipase A2-activating protein
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RNASEH2B ribonuclease H2, subunit B
RNF2 ring finger protein 2
RPL37A ribosomal protein L37a
RPL7 ribosomal protein L7
RPS9 ribosomal protein S9
RUNX3 runt-related transcription factor 3
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SETD1A SET domain containing 1A
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMG6 SMG6 nonsense mediated mRNA decay factor
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPN sialophorin
STAC SH3 and cysteine rich domain
STS steroid sulfatase (microsomal), isozyme S
STX2 syntaxin 2
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYT17 synaptotagmin XVII
TADA2A transcriptional adaptor 2A
TBX19 T-box 19
TEAD3 TEA domain family member 3
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFEB transcription factor EB
TK2 thymidine kinase 2, mitochondrial
TMEM47 transmembrane protein 47
TMEM53 transmembrane protein 53
TMEM63A transmembrane protein 63A
TPM2 tropomyosin 2 (beta)
TRIM14 tripartite motif containing 14
TRIO trio Rho guanine nucleotide exchange factor
TUBA3C tubulin, alpha 3c
UBE3A ubiquitin protein ligase E3A
UBQLN4 ubiquilin 4
VAC14 Vac14 homolog (S. cerevisiae)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VEZT vezatin, adherens junctions transmembrane protein
ZBTB3 zinc finger and BTB domain containing 3
ZNF224 zinc finger protein 224
ZNF623 zinc finger protein 623
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
ADAM15 ADAM metallopeptidase domain 15
ANKHD1 ankyrin repeat and KH domain containing 1
ATAD5 ATPase family, AAA domain containing 5
BCAS3 breast carcinoma amplified sequence 3
C16ORF59 chromosome 16 open reading frame 59
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
C8ORF44 chromosome 8 open reading frame 44
CBX4 chromobox homolog 4
CD70 CD70 molecule
CEP72 centrosomal protein 72kDa
CISH cytokine inducible SH2-containing protein
CPOX coproporphyrinogen oxidase
CREB5 cAMP responsive element binding protein 5
CTGF connective tissue growth factor
CXCL3 chemokine (C-X-C motif) ligand 3
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DTX4 deltex 4, E3 ubiquitin ligase
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ETAA1 Ewing tumor-associated antigen 1
EXOC5 exocyst complex component 5
FAM188A family with sequence similarity 188, member A
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FZD3 frizzled class receptor 3
GALT galactose-1-phosphate uridylyltransferase
GPR137B G protein-coupled receptor 137B
H1F0 H1 histone family, member 0
HIRA histone cell cycle regulator
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IGFLR1 IGF-like family receptor 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0232 KIAA0232
KIF13A kinesin family member 13A
LIN7B lin-7 homolog B (C. elegans)
LINC00260 long intergenic non-protein coding RNA 260
LMBRD1 LMBR1 domain containing 1
LMNB1 lamin B1
LOC100127972 uncharacterized LOC100127972
LONRF3 LON peptidase N-terminal domain and ring finger 3
MANEA mannosidase, endo-alpha
MYLIP myosin regulatory light chain interacting protein
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOZ3 myozenin 3
NCS1 neuronal calcium sensor 1
NHLRC2 NHL repeat containing 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
OCEL1 occludin/ELL domain containing 1
ODF2 outer dense fiber of sperm tails 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PCTP phosphatidylcholine transfer protein
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIBF1 progesterone immunomodulatory binding factor 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLXNB3 plexin B3
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PSENEN presenilin enhancer gamma secretase subunit
PTK6 protein tyrosine kinase 6
RCL1 RNA terminal phosphate cyclase-like 1
RNF38 ring finger protein 38
RPS2P45 ribosomal protein S2 pseudogene 45
SCML1 sex comb on midleg-like 1 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC17A2 solute carrier family 17, member 2
SLC22A18 solute carrier family 22, member 18
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC41A3 solute carrier family 41, member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNX24 sorting nexin 24
SRBD1 S1 RNA binding domain 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM230 transmembrane protein 230
TMEM242 transmembrane protein 242
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRIM9 tripartite motif containing 9
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSPAN1 tetraspanin 1
WDR37 WD repeat domain 37
YAF2 YY1 associated factor 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YIPF5 Yip1 domain family, member 5
ZC3H7A zinc finger CCCH-type containing 7A
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF107 zinc finger protein 107
ZNF226 zinc finger protein 226