BCB000038-7516 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the BCB000038-7516 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACBD4 acyl-CoA binding domain containing 4
ACOX2 acyl-CoA oxidase 2, branched chain
ACRV1 acrosomal vesicle protein 1
AK2 adenylate kinase 2
ALOXE3 arachidonate lipoxygenase 3
ALPK1 alpha-kinase 1
AMPD1 adenosine monophosphate deaminase 1
ANGEL2 angel homolog 2 (Drosophila)
ARHGAP11A Rho GTPase activating protein 11A
C16ORF70 chromosome 16 open reading frame 70
CA14 carbonic anhydrase XIV
CALML5 calmodulin-like 5
CDH8 cadherin 8, type 2
CDK3 cyclin-dependent kinase 3
CHST10 carbohydrate sulfotransferase 10
CIDEC cell death-inducing DFFA-like effector c
CLSPN claspin
CTSV cathepsin V
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DRD1 dopamine receptor D1
DSC3 desmocollin 3
EPHA2 EPH receptor A2
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO2 F-box protein 2
FMO5 flavin containing monooxygenase 5
FOXI1 forkhead box I1
FYB FYN binding protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPC4 glypican 4
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC11 histone deacetylase 11
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA11 homeobox A11
IFI30 interferon, gamma-inducible protein 30
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL11 interleukin 11
INSR insulin receptor
IQCC IQ motif containing C
ITGA6 integrin, alpha 6
JMJD4 jumonji domain containing 4
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIF5C kinesin family member 5C
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KREMEN2 kringle containing transmembrane protein 2
LTBP4 latent transforming growth factor beta binding protein 4
LZTFL1 leucine zipper transcription factor-like 1
MRPL44 mitochondrial ribosomal protein L44
MSL3 male-specific lethal 3 homolog (Drosophila)
MTSS1L metastasis suppressor 1-like
MYO1B myosin IB
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NLRX1 NLR family member X1
OASL 2'-5'-oligoadenylate synthetase-like
OXT oxytocin/neurophysin I prepropeptide
PAIP2B poly(A) binding protein interacting protein 2B
PBX2 pre-B-cell leukemia homeobox 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POT1 protection of telomeres 1
PPARD peroxisome proliferator-activated receptor delta
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTHLH parathyroid hormone-like hormone
RAB3D RAB3D, member RAS oncogene family
RARS arginyl-tRNA synthetase
RIC3 RIC3 acetylcholine receptor chaperone
RND2 Rho family GTPase 2
RPL10 ribosomal protein L10
RRP1B ribosomal RNA processing 1B
SBNO2 strawberry notch homolog 2 (Drosophila)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMAD5 SMAD family member 5
SMG7-AS1 SMG7 antisense RNA 1
SOX15 SRY (sex determining region Y)-box 15
SPAG8 sperm associated antigen 8
SPINK5 serine peptidase inhibitor, Kazal type 5
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK24 serine/threonine kinase 24
T T, brachyury homolog (mouse)
TBL1X transducin (beta)-like 1X-linked
TCF4 transcription factor 4
TICAM1 toll-like receptor adaptor molecule 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
ULK2 unc-51 like autophagy activating kinase 2
UNC5B unc-5 homolog B (C. elegans)
WNK1 WNK lysine deficient protein kinase 1
ZFHX4 zinc finger homeobox 4
ZNF35 zinc finger protein 35
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AZI2 5-azacytidine induced 2
BEGAIN brain-enriched guanylate kinase-associated
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRIX1 BRX1, biogenesis of ribosomes
C17ORF53 chromosome 17 open reading frame 53
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC186 coiled-coil domain containing 186
CCDC88C coiled-coil domain containing 88C
CCDC94 coiled-coil domain containing 94
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CEP72 centrosomal protein 72kDa
CLDND1 claudin domain containing 1
COCH cochlin
CSTA cystatin A (stefin A)
DCAF13 DDB1 and CUL4 associated factor 13
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
F8 coagulation factor VIII, procoagulant component
FANCE Fanconi anemia, complementation group E
FAP fibroblast activation protein, alpha
FGD1 FYVE, RhoGEF and PH domain containing 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIN1 gypsy retrotransposon integrase 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H4C histone cluster 1, H4c
HMHA1 histocompatibility (minor) HA-1
HOXC5 homeobox C5
HS1BP3 HCLS1 binding protein 3
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCTD7 potassium channel tetramerization domain containing 7
KIF13B kinesin family member 13B
KIF5A kinesin family member 5A
KLHL25 kelch-like family member 25
KLK8 kallikrein-related peptidase 8
KRT15 keratin 15, type I
LAMP5 lysosomal-associated membrane protein family, member 5
LNPEP leucyl/cystinyl aminopeptidase
LOC257152 uncharacterized LOC257152
LTC4S leukotriene C4 synthase
MFAP2 microfibrillar-associated protein 2
MT3 metallothionein 3
MTMR11 myotubularin related protein 11
MYO1E myosin IE
OCA2 oculocutaneous albinism II
PCBP3 poly(rC) binding protein 3
PCNXL4 pecanex-like 4 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKD2L1 polycystic kidney disease 2-like 1
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTPRM protein tyrosine phosphatase, receptor type, M
PTPRU protein tyrosine phosphatase, receptor type, U
RAB3A RAB3A, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
REPS2 RALBP1 associated Eps domain containing 2
RFX7 regulatory factor X, 7
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROM1 retinal outer segment membrane protein 1
RPGR retinitis pigmentosa GTPase regulator
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RSF1 remodeling and spacing factor 1
RWDD3 RWD domain containing 3
SAA4 serum amyloid A4, constitutive
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STRA6 stimulated by retinoic acid 6
TBC1D17 TBC1 domain family, member 17
TBC1D2 TBC1 domain family, member 2
TCTN2 tectonic family member 2
TMEM2 transmembrane protein 2
TMEM38B transmembrane protein 38B
TMPRSS4 transmembrane protease, serine 4
TTC26 tetratricopeptide repeat domain 26
TTLL1 tubulin tyrosine ligase-like family member 1
WLS wntless Wnt ligand secretion mediator
ZC3H12A zinc finger CCCH-type containing 12A
ZFP30 ZFP30 zinc finger protein
ZMAT3 zinc finger, matrin-type 3
ZNF254 zinc finger protein 254
ZNF446 zinc finger protein 446
ZNF586 zinc finger protein 586
ZNF76 zinc finger protein 76