BAS-012416453-6880 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the BAS-012416453-6880 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
ALCAM activated leukocyte cell adhesion molecule
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ANKRD36 ankyrin repeat domain 36
APP amyloid beta (A4) precursor protein
ARFRP1 ADP-ribosylation factor related protein 1
ARHGAP44 Rho GTPase activating protein 44
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARNT aryl hydrocarbon receptor nuclear translocator
ASB1 ankyrin repeat and SOCS box containing 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
BCL9 B-cell CLL/lymphoma 9
BRD4 bromodomain containing 4
C11ORF80 chromosome 11 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCHCR1 coiled-coil alpha-helical rod protein 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COPZ2 coatomer protein complex, subunit zeta 2
CSNK1E casein kinase 1, epsilon
CXORF56 chromosome X open reading frame 56
DACH1 dachshund family transcription factor 1
DTNA dystrobrevin, alpha
DTX2 deltex 2, E3 ubiquitin ligase
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
ESR1 estrogen receptor 1
FAM131A family with sequence similarity 131, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FKBP10 FK506 binding protein 10, 65 kDa
FLOT1 flotillin 1
GBP2 guanylate binding protein 2, interferon-inducible
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPC1 glypican 1
GSTCD glutathione S-transferase, C-terminal domain containing
HEXA hexosaminidase A (alpha polypeptide)
HLA-G major histocompatibility complex, class I, G
IFI6 interferon, alpha-inducible protein 6
INADL InaD-like (Drosophila)
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB5 integrin, beta 5
JUND jun D proto-oncogene
KLC2 kinesin light chain 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBTD1 mbt domain containing 1
MCL1 myeloid cell leukemia 1
MCM3AP minichromosome maintenance complex component 3 associated protein
MSL3 male-specific lethal 3 homolog (Drosophila)
MT1E metallothionein 1E
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
MVP major vault protein
MYO9A myosin IXA
NDE1 nudE neurodevelopment protein 1
NYNRIN NYN domain and retroviral integrase containing
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM7 PDZ and LIM domain 7 (enigma)
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G15 phospholipase A2, group XV
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PSD4 pleckstrin and Sec7 domain containing 4
QKI QKI, KH domain containing, RNA binding
RAD51B RAD51 paralog B
RGS10 regulator of G-protein signaling 10
RNF19B ring finger protein 19B
RNFT1 ring finger protein, transmembrane 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SDC2 syndecan 2
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SHOX2 short stature homeobox 2
SIRT6 sirtuin 6
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNX1 sorting nexin 1
SS18 synovial sarcoma translocation, chromosome 18
TADA2A transcriptional adaptor 2A
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN transgelin
TCP11L1 t-complex 11, testis-specific-like 1
TEX261 testis expressed 261
TLE2 transducin-like enhancer of split 2
TMCC1 transmembrane and coiled-coil domain family 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIM36 tripartite motif containing 36
TRIM66 tripartite motif containing 66
UBXN6 UBX domain protein 6
YIPF4 Yip1 domain family, member 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF16 zinc finger protein 16
ZNF37BP zinc finger protein 37B, pseudogene
ZNF557 zinc finger protein 557
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADM adrenomedullin
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBS7 Bardet-Biedl syndrome 7
BFSP1 beaded filament structural protein 1, filensin
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C19ORF73 chromosome 19 open reading frame 73
C21ORF91 chromosome 21 open reading frame 91
CAMKMT calmodulin-lysine N-methyltransferase
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFAP44 cilia and flagella associated protein 44
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIR1 corepressor interacting with RBPJ, 1
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DCAF17 DDB1 and CUL4 associated factor 17
DENND4A DENN/MADD domain containing 4A
E2F3 E2F transcription factor 3
ECHDC2 enoyl CoA hydratase domain containing 2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
FADS2 fatty acid desaturase 2
FAM186A family with sequence similarity 186, member A
FAM188A family with sequence similarity 188, member A
FBXO4 F-box protein 4
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCHSD2 FCH and double SH3 domains 2
FLJ11710 uncharacterized protein FLJ11710
GADD45G growth arrest and DNA-damage-inducible, gamma
GEM GTP binding protein overexpressed in skeletal muscle
GFI1 growth factor independent 1 transcription repressor
GMEB1 glucocorticoid modulatory element binding protein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR157 G protein-coupled receptor 157
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCFC2 host cell factor C2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIRA histone cell cycle regulator
HIST1H1B histone cluster 1, H1b
HMOX1 heme oxygenase 1
HOXC4 homeobox C4
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
LIG4 ligase IV, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LOC100287590 uncharacterized LOC100287590
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD1 LY6/PLAUR domain containing 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MOCS3 molybdenum cofactor synthesis 3
MYO3A myosin IIIA
NR2C2 nuclear receptor subfamily 2, group C, member 2
OSGIN1 oxidative stress induced growth inhibitor 1
PADI3 peptidyl arginine deiminase, type III
PCOLCE procollagen C-endopeptidase enhancer
PDE8B phosphodiesterase 8B
PKD2L1 polycystic kidney disease 2-like 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PP14571 uncharacterized LOC100130449
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
RPGR retinitis pigmentosa GTPase regulator
SCAMP5 secretory carrier membrane protein 5
SCNN1B sodium channel, non voltage gated 1 beta subunit
SECISBP2 SECIS binding protein 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD1A SET domain containing 1A
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOAT2 sterol O-acyltransferase 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
STRN striatin, calmodulin binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX19 T-box 19
TCTN2 tectonic family member 2
THRAP3 thyroid hormone receptor associated protein 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM53 transmembrane protein 53
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
WRN Werner syndrome, RecQ helicase-like
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF136 zinc finger protein 136
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF668 zinc finger protein 668