B cell activation Gene Set

Dataset PANTHER Pathways
Category structural or functional annotations
Type pathway
Description The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. (Gene Ontology, GO_0042113)
External Link http://www.pantherdb.org/pathway/pathDetail.do?clsAccession=P00010
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Genes

53 proteins participating in the B cell activation pathway from the PANTHER Pathways dataset.

Symbol Name
ARAF A-Raf proto-oncogene, serine/threonine kinase
BLNK B-cell linker
BTK Bruton agammaglobulinemia tyrosine kinase
CD19 CD19 molecule
CD22 CD22 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CHUK conserved helix-loop-helix ubiquitous kinase
FOS FBJ murine osteosarcoma viral oncogene homolog
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUN jun proto-oncogene
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SYK spleen tyrosine kinase
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor