Autoimmune Diseases Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

269 genes associated with the Autoimmune Diseases phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
AIF1 allograft inflammatory factor 1
AIRE autoimmune regulator
ANKRD55 ankyrin repeat domain 55
ANXA5 annexin A5
APOH apolipoprotein H (beta-2-glycoprotein I)
AR androgen receptor
ARID5B AT rich interactive domain 5B (MRF1-like)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG5 autophagy related 5
ATXN2 ataxin 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAK1 BCL2-antagonist/killer 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP15 bone morphogenetic protein 15
BUD13 BUD13 homolog (S. cerevisiae)
C1QTNF6 C1q and tumor necrosis factor related protein 6
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C5 complement component 5
CAPZB capping protein (actin filament) muscle Z-line, beta
CCL21 chemokine (C-C motif) ligand 21
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCR3 chemokine (C-C motif) receptor 3
CD226 CD226 molecule
CD274 CD274 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD58 CD58 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDHR5 cadherin-related family member 5
CDK6 cyclin-dependent kinase 6
CDKN2B-AS1 CDKN2B antisense RNA 1
CFH complement factor H
CFI complement factor I
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIITA class II, major histocompatibility complex, transactivator
CLEC16A C-type lectin domain family 16, member A
COL11A2 collagen, type XI, alpha 2
COTL1 coactosin-like F-actin binding protein 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSH cathepsin H
CXCL12 chemokine (C-X-C motif) ligand 12
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DCC DCC netrin 1 receptor
DEFB1 defensin, beta 1
DERL3 derlin 3
DNASE1 deoxyribonuclease I
DUSP10 dual specificity phosphatase 10
ELF5 E74-like factor 5 (ets domain transcription factor)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERBB3 erb-b2 receptor tyrosine kinase 3
ERVK-18 endogenous retrovirus group K, member 18
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FAM167A family with sequence similarity 167, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCRL3 Fc receptor-like 3
FMR1 fragile X mental retardation 1
FOXE1 forkhead box E1
FOXP3 forkhead box P3
FSHR follicle stimulating hormone receptor
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GDF9 growth differentiation factor 9
GSDMB gasdermin B
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR1 hepatitis A virus cellular receptor 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HSPA1B heat shock 70kDa protein 1B
IBD5 inflammatory bowel disease 5
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IFIH1 interferon induced with helicase C domain 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNW1 interferon, omega 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF4 IKAROS family zinc finger 4 (Eos)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL23R interleukin 23 receptor
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
INS insulin
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
IRGM immunity-related GTPase family, M
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
JAK2 Janus kinase 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIAA1109 KIAA1109
KIF5A kinesin family member 5A
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LCE3B late cornified envelope 3B
LCE3C late cornified envelope 3C
LGALS8 lectin, galactoside-binding, soluble, 8
LPP LIM domain containing preferred translocation partner in lipoma
LTA lymphotoxin alpha
LYN LYN proto-oncogene, Src family tyrosine kinase
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MCPH1 microcephalin 1
MEFV Mediterranean fever
MEN1 multiple endocrine neoplasia I
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146A microRNA 146a
MIR499A microRNA 499a
MPO myeloperoxidase
MST1 macrophage stimulating 1
MT-TL1 tRNA
MVK mevalonate kinase
MYO9B myosin IXB
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOD2 nucleotide-binding oligomerization domain containing 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRXN3 neurexin 3
OLIG3 oligodendrocyte transcription factor 3
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PADI4 peptidyl arginine deiminase, type IV
PDCD1 programmed cell death 1
PDE8B phosphodiesterase 8B
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHRF1 PHD and ring finger domains 1
PLCL1 phospholipase C-like 1
PRDX5 peroxiredoxin 5
PRF1 perforin 1 (pore forming protein)
PRL prolactin
PRLR prolactin receptor
PRSS1 protease, serine, 1 (trypsin 1)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTTG1 pituitary tumor-transforming 1
PXK PX domain containing serine/threonine kinase
RAET1L retinoic acid early transcript 1L
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS1 regulator of G-protein signaling 1
RSBN1 round spermatid basic protein 1
RTEL1 regulator of telomere elongation helicase 1
RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate)
SCUBE1 signal peptide, CUB domain, EGF-like 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SEZ6L seizure related 6 homolog (mouse)-like
SH2B3 SH2B adaptor protein 3
SIAE sialic acid acetylesterase
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMOC2 SPARC related modular calcium binding 2
SPINK1 serine peptidase inhibitor, Kazal type 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STX17 syntaxin 17
SUMO4 small ubiquitin-like modifier 4
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TAGAP T-cell activation RhoGTPase activating protein
TAPBP TAP binding protein (tapasin)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDRD10 tudor domain containing 10
TERT telomerase reverse transcriptase
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
TRAF1 TNF receptor-associated factor 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRB T cell receptor beta locus
TRIB3 tribbles pseudokinase 3
TSHR thyroid stimulating hormone receptor
TYK2 tyrosine kinase 2
TYR tyrosinase
UBASH3A ubiquitin associated and SH3 domain containing A
UBE2L3 ubiquitin-conjugating enzyme E2L 3
ULBP3 UL16 binding protein 3
VAV3 vav 3 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VTCN1 V-set domain containing T cell activation inhibitor 1
XKR6 XK, Kell blood group complex subunit-related family, member 6
ZFP36 ZFP36 ring finger protein
ZPBP2 zona pellucida binding protein 2