Atrophy Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Similar Terms
Downloads & Tools

Genes

96 genes associated with the Atrophy phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOA1 apolipoprotein A-I
APOE apolipoprotein E
ARMS2 age-related maculopathy susceptibility 2
ARPP21 cAMP-regulated phosphoprotein, 21kDa
B3GAT1 beta-1,3-glucuronyltransferase 1
B3GAT2 beta-1,3-glucuronyltransferase 2
BCAN brevican
BDNF brain-derived neurotrophic factor
BIN1 bridging integrator 1
C9ORF72 chromosome 9 open reading frame 72
CARD10 caspase recruitment domain family, member 10
CD14 CD14 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD58 CD58 molecule
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CHST10 carbohydrate sulfotransferase 10
CLEC16A C-type lectin domain family 16, member A
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DIO1 deiodinase, iodothyronine, type I
DIO2 deiodinase, iodothyronine, type II
DISC1 disrupted in schizophrenia 1
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAS Fas cell surface death receptor
FGFR1OP2 FGFR1 oncogene partner 2
GAB1 GRB2-associated binding protein 1
GOLM1 golgi membrane protein 1
GRN granulin
GSK3A glycogen synthase kinase 3 alpha
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HAPLN2 hyaluronan and proteoglycan link protein 2
HAPLN3 hyaluronan and proteoglycan link protein 3
HAPLN4 hyaluronan and proteoglycan link protein 4
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTT huntingtin
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL7R interleukin 7 receptor
LTA lymphotoxin alpha
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR137 microRNA 137
MMP7 matrix metallopeptidase 7
MPO myeloperoxidase
MT-TL1 tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NCAN neurocan
NOD1 nucleotide-binding oligomerization domain containing 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRG1 neuregulin 1
OGG1 8-oxoguanine DNA glycosylase
PARP1 poly (ADP-ribose) polymerase 1
PAX6 paired box 6
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCM1 pericentriolar material 1
PICALM phosphatidylinositol binding clathrin assembly protein
PSEN1 presenilin 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RPL5 ribosomal protein L5
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNR tenascin R
TSNAX translin-associated factor X
TTR transthyretin
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
VEGFA vascular endothelial growth factor A
ZNF224 zinc finger protein 224
ZNF292 zinc finger protein 292