Asthenozoospermia Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description loss or reduction of the mobility of the spermatozoa, frequently associated with infertility (Mammalian Phenotype Ontology, MP_0002675)
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23 genes associated with the Asthenozoospermia phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
APOB apolipoprotein B
AR androgen receptor
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCA4 chloride channel accessory 4
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DPF3 D4, zinc and double PHD fingers, family 3
DSCAML1 Down syndrome cell adhesion molecule like 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPHX2 epoxide hydrolase 2, cytoplasmic
FSHR follicle stimulating hormone receptor
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HFE hemochromatosis
IL6 interleukin 6
KLHL10 kelch-like family member 10
MT-CYB cytochrome b
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
NFE2L2 nuclear factor, erythroid 2-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
SLC26A8 solute carrier family 26 (anion exchanger), member 8
TNF tumor necrosis factor