Ascariasis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A parasitic helminthiasis infectious disease that involves infection of the intestine with the nematode Ascaris lumbricoides. Larvae migrating through the lungs cause cough, wheezing and hemoptysis. Bowel or biliary obstruction causes cramping abdominal pain, nausea, and vomiting. Peritonitis, enlargement of the liver or spleen, toxicity and pneumonia are observed when larvae get into the portal circulation. (Human Disease Ontology, DOID_456)
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Genes

5 genes associated with the Ascariasis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
IRS2 insulin receptor substrate 2
LIG4 ligase IV, DNA, ATP-dependent
PTPRC protein tyrosine phosphatase, receptor type, C
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b