Arthritis, Juvenile Rheumatoid Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

147 genes associated with the Arthritis, Juvenile Rheumatoid phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ADAD1 adenosine deaminase domain containing 1 (testis-specific)
ADORA2A adenosine A2a receptor
ADRB2 adrenoceptor beta 2, surface
AFF3 AF4/FMR2 family, member 3
AMPD1 adenosine monophosphate deaminase 1
ANGPT1 angiopoietin 1
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATXN2 ataxin 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C5 complement component 5
CALCR calcitonin receptor
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL5 chemokine (C-C motif) ligand 5
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD226 CD226 molecule
CD247 CD247 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD80 CD80 molecule
CDK6 cyclin-dependent kinase 6
CIITA class II, major histocompatibility complex, transactivator
CLEC16A C-type lectin domain family 16, member A
COG6 component of oligomeric golgi complex 6
CRH corticotropin releasing hormone
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSH cathepsin H
CXCL8 chemokine (C-X-C motif) ligand 8
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DDR1 discoidin domain receptor tyrosine kinase 1
DHFR dihydrofolate reductase
ERAP1 endoplasmic reticulum aminopeptidase 1
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
FAM177A1 family with sequence similarity 177, member A1
FAS Fas cell surface death receptor
FCAMR Fc receptor, IgA, IgM, high affinity
FCRL3 Fc receptor-like 3
FOXP3 forkhead box P3
FPGS folylpolyglutamate synthase
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IL10 interleukin 10
IL11RA interleukin 11 receptor, alpha
IL12A interleukin 12A
IL13 interleukin 13
IL18 interleukin 18
IL18RAP interleukin 18 receptor accessory protein
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20 interleukin 20
IL21 interleukin 21
IL23R interleukin 23 receptor
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL7R interleukin 7 receptor
INS insulin
IRF1 interferon regulatory factor 1
IRF5 interferon regulatory factor 5
IRF6 interferon regulatory factor 6
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JMJD1C jumonji domain containing 1C
KIAA0391 KIAA0391
KIF5A kinesin family member 5A
LPP LIM domain containing preferred translocation partner in lipoma
LTA lymphotoxin alpha
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146A microRNA 146a
MMEL1 membrane metallo-endopeptidase-like 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
PRF1 perforin 1 (pore forming protein)
PRKCQ protein kinase C, theta
PRL prolactin
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RAB27A RAB27A, member RAS oncogene family
RGS1 regulator of G-protein signaling 1
RSBN1 round spermatid basic protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SH2B3 SH2B adaptor protein 3
SH2D2A SH2 domain containing 2A
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC46A1 solute carrier family 46 (folate transporter), member 1
STAT4 signal transducer and activator of transcription 4
SUMO4 small ubiquitin-like modifier 4
TAGAP T-cell activation RhoGTPase activating protein
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TGFB1 transforming growth factor, beta 1
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRAF1 TNF receptor-associated factor 1
TYMS thymidylate synthetase
UBASH3A ubiquitin associated and SH3 domain containing A
UNC13D unc-13 homolog D (C. elegans)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VTCN1 V-set domain containing T cell activation inhibitor 1