Arachidonic acid metabolism Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. (Gene Ontology, GO_0019369)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-2142753
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Genes

50 proteins participating in the Arachidonic acid metabolism pathway from the Reactome Pathways dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
AKR1C3 aldo-keto reductase family 1, member C3
ALOX12 arachidonate 12-lipoxygenase
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
CBR1 carbonyl reductase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
DPEP1 dipeptidase 1 (renal)
DPEP2 dipeptidase 2
DPEP3 dipeptidase 3
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM213B family with sequence similarity 213, member B
GGT1 gamma-glutamyltransferase 1
GGT5 gamma-glutamyltransferase 5
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX4 glutathione peroxidase 4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPGDS hematopoietic prostaglandin D synthase
LTA4H leukotriene A4 hydrolase
LTC4S leukotriene C4 synthase
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES prostaglandin E synthase
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGR1 prostaglandin reductase 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
TBXAS1 thromboxane A synthase 1 (platelet)