Antisocial Personality Disorder Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A personality disorder that involves a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. (Human Disease Ontology, DOID_10939)
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Genes

42 genes associated with the Antisocial Personality Disorder phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKK1 ankyrin repeat and kinase domain containing 1
AR androgen receptor
AVPR1A arginine vasopressin receptor 1A
BDNF brain-derived neurotrophic factor
CHRM2 cholinergic receptor, muscarinic 2
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
COL25A1 collagen, type XXV, alpha 1
COMT catechol-O-methyltransferase
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ESR1 estrogen receptor 1
FAAH fatty acid amide hydrolase
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
LMX1B LIM homeobox transcription factor 1, beta
MAOA monoamine oxidase A
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRM1 opioid receptor, mu 1
OXTR oxytocin receptor
PRKCG protein kinase C, gamma
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TH tyrosine hydroxylase
TMPRSS9 transmembrane protease, serine 9
TPH1 tryptophan hydroxylase 1