Angina Pectoris Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Paroxysmal chest pain that occurs with exertion or stress and is related to myocardial ischemia. (Human Phenotype Ontology, HP_0001681)
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Genes

59 genes associated with the Angina Pectoris phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACE angiotensin I converting enzyme
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANGPT1 angiopoietin 1
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
C4B complement component 4B (Chido blood group)
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CD36 CD36 molecule (thrombospondin receptor)
CMA1 chymase 1, mast cell
CPB2 carboxypeptidase B2 (plasma)
CYBA cytochrome b-245, alpha polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DNASE1 deoxyribonuclease I
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGB fibrinogen beta chain
GAS6 growth arrest-specific 6
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL10 interleukin 10
IL1A interleukin 1, alpha
IL6 interleukin 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KDR kinase insert domain receptor
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LIPC lipase, hepatic
LPL lipoprotein lipase
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PECAM1 platelet/endothelial cell adhesion molecule 1
PON1 paraoxonase 1
PROCR protein C receptor, endothelial
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C