Anemia, Sideroblastic Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An aplastic anemia where the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). (Human Disease Ontology, DOID_8955)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D000756
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Genes

48 genes/proteins associated with the disease Anemia, Sideroblastic from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GLRX5 glutaredoxin 5 2.88009
GDF15 growth differentiation factor 15 2.88009
SLC25A38 solute carrier family 25, member 38 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 2.88009
ALAS2 5'-aminolevulinate synthase 2 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.59567
BCL2 B-cell CLL/lymphoma 2 1.50018
IL6 interleukin 6 1.44817
DDIT3 DNA-damage-inducible transcript 3 1.39841
TGFB1 transforming growth factor, beta 1 1.39646
IL1B interleukin 1, beta 1.38185
TNF tumor necrosis factor 1.37561
NOS2 nitric oxide synthase 2, inducible 1.23743
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.20622
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.20295
TFRC transferrin receptor 1.1753
BMP4 bone morphogenetic protein 4 1.1753
TP53 tumor protein p53 1.13655
HMOX1 heme oxygenase 1 1.13586
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.13484
CAT catalase 1.13211
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.12048
MMP13 matrix metallopeptidase 13 1.10872
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.10769
ATM ATM serine/threonine kinase 1.09611
TF transferrin 1.09332
GADD45A growth arrest and DNA-damage-inducible, alpha 1.07376
CCL2 chemokine (C-C motif) ligand 2 1.06917
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.06625
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.052
GSTT1 glutathione S-transferase theta 1 1.05089
ACO2 aconitase 2, mitochondrial 1.05052
CRP C-reactive protein, pentraxin-related 1.04757
MMP1 matrix metallopeptidase 1 1.04126
APP amyloid beta (A4) precursor protein 1.04126
EPAS1 endothelial PAS domain protein 1 1.03789
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.03752
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.03604
MAPK3 mitogen-activated protein kinase 3 1.0353
KLF4 Kruppel-like factor 4 (gut) 1.03382
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.03235
MAPK1 mitogen-activated protein kinase 1 1.02671
B2M beta-2-microglobulin 1.02634
MPO myeloperoxidase 1.01549
MBP myelin basic protein 1.01474
IGF1 insulin-like growth factor 1 (somatomedin C) 1.01399
HEPH hephaestin 1.01137