Anemia, Hemolytic, Autoimmune Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D000744
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Genes

270 genes/proteins associated with the disease Anemia, Hemolytic, Autoimmune from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 2.88009
TNF tumor necrosis factor 2.26363
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.20175
IL1B interleukin 1, beta 1.9896
IL6 interleukin 6 1.95631
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.92265
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.88409
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.81111
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.8068
CXCL8 chemokine (C-X-C motif) ligand 8 1.79178
DDIT3 DNA-damage-inducible transcript 3 1.75875
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.74601
CAT catalase 1.72968
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.72364
ALB albumin 1.71358
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.68358
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.66792
UNG uracil-DNA glycosylase 1.6593
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.63586
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.62983
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.6287
IFNG interferon, gamma 1.61944
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.6169
GSTP1 glutathione S-transferase pi 1 1.60082
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.58303
IL4 interleukin 4 1.58018
PRL prolactin 1.57782
GCLM glutamate-cysteine ligase, modifier subunit 1.57162
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.56971
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.55946
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.55353
NQO1 NAD(P)H dehydrogenase, quinone 1 1.54693
TGFB1 transforming growth factor, beta 1 1.53965
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.53917
IL1A interleukin 1, alpha 1.53555
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.5284
TP53 tumor protein p53 1.51961
BCL2 B-cell CLL/lymphoma 2 1.51936
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.51582
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.5103
TAGLN transgelin 1.50801
MMP3 matrix metallopeptidase 3 1.50348
HSPA1A heat shock 70kDa protein 1A 1.50273
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.49278
PCNA proliferating cell nuclear antigen 1.4575
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.45431
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.45194
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.45009
FAS Fas cell surface death receptor 1.44626
HMOX1 heme oxygenase 1 1.43974
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.43537
C10ORF10 chromosome 10 open reading frame 10 1.4294
CLU clusterin 1.42831
BAX BCL2-associated X protein 1.42321
NUPR1 nuclear protein, transcriptional regulator, 1 1.42074
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.40401
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.40316
GADD45A growth arrest and DNA-damage-inducible, alpha 1.40064
NES nestin 1.37332
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 1.3619
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.35041
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.35041
EPO erythropoietin 1.34576
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.34489
BCL2L1 BCL2-like 1 1.34401
ADM adrenomedullin 1.34169
TAT tyrosine aminotransferase 1.33995
CCL2 chemokine (C-C motif) ligand 2 1.33909
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.3388
IL10 interleukin 10 1.33405
FABP1 fatty acid binding protein 1, liver 1.33375
VEGFA vascular endothelial growth factor A 1.32993
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.32816
MPO myeloperoxidase 1.32696
INHBE inhibin, beta E 1.32577
SAT1 spermidine/spermine N1-acetyltransferase 1 1.32577
ICAM1 intercellular adhesion molecule 1 1.32369
CCND1 cyclin D1 1.32369
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.32074
SOD2 superoxide dismutase 2, mitochondrial 1.31807
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.31387
PHYH phytanoyl-CoA 2-hydroxylase 1.31237
PDLIM7 PDZ and LIM domain 7 (enigma) 1.31237
MMP2 matrix metallopeptidase 2 1.29905
DUSP1 dual specificity phosphatase 1 1.29781
EPAS1 endothelial PAS domain protein 1 1.29379
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.29256
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.28456
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.28364
MAPK8 mitogen-activated protein kinase 8 1.28119
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.2707
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.26052
FOS FBJ murine osteosarcoma viral oncogene homolog 1.25682
NOS2 nitric oxide synthase 2, inducible 1.25369
CDK2 cyclin-dependent kinase 2 1.25307
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.25245
GCLC glutamate-cysteine ligase, catalytic subunit 1.2509
DHFR dihydrofolate reductase 1.24905
ADIPOR2 adiponectin receptor 2 1.24905
ATF3 activating transcription factor 3 1.24843
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.2475
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.24687
IGFBP5 insulin-like growth factor binding protein 5 1.24465
EGR1 early growth response 1 1.24433
S100A9 S100 calcium binding protein A9 1.24244
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.24213
JUN jun proto-oncogene 1.23488
MAPK3 mitogen-activated protein kinase 3 1.22727
PHIP pleckstrin homology domain interacting protein 1.2208
GLB1L galactosidase, beta 1-like 1.21823
PARP1 poly (ADP-ribose) polymerase 1 1.21791
GPX2 glutathione peroxidase 2 1.21727
CDKN2A cyclin-dependent kinase inhibitor 2A 1.21695
HSPA8 heat shock 70kDa protein 8 1.21695
MAPK1 mitogen-activated protein kinase 1 1.21599
PLAT plasminogen activator, tissue 1.20848
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.2059
NFE2L1 nuclear factor, erythroid 2-like 1 1.2013
TIMP1 TIMP metallopeptidase inhibitor 1 1.20064
RRM2 ribonucleotide reductase M2 1.1977
FNBP1 formin binding protein 1 1.19639
CCND3 cyclin D3 1.19379
GPX3 glutathione peroxidase 3 1.1862
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.18093
ODC1 ornithine decarboxylase 1 1.18059
ACSL6 acyl-CoA synthetase long-chain family member 6 1.1786
MSH2 mutS homolog 2 1.17761
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.1753
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.17497
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 1.17431
GINS1 GINS complex subunit 1 (Psf1 homolog) 1.17431
SYNM synemin, intermediate filament protein 1.17366
ERBB2 erb-b2 receptor tyrosine kinase 2 1.16666
PALLD palladin, cytoskeletal associated protein 1.16567
IGFBP1 insulin-like growth factor binding protein 1 1.16302
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.16001
CDC25B cell division cycle 25B 1.15967
HLA-G major histocompatibility complex, class I, G 1.15797
CCNE1 cyclin E1 1.15729
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.15256
LYPLAL1 lysophospholipase-like 1 1.15022
KLF4 Kruppel-like factor 4 (gut) 1.14989
EGF epidermal growth factor 1.14989
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.14781
CCNA2 cyclin A2 1.14747
APP amyloid beta (A4) precursor protein 1.14438
GRB10 growth factor receptor-bound protein 10 1.142
BTG3 BTG family, member 3 1.142
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.1403
TXNRD1 thioredoxin reductase 1 1.13895
SOD1 superoxide dismutase 1, soluble 1.13827
EBI3 Epstein-Barr virus induced 3 1.13586
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.13552
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.13313
SNAP29 synaptosomal-associated protein, 29kDa 1.12906
BUB3 BUB3 mitotic checkpoint protein 1.12906
MAGED1 melanoma antigen family D1 1.12906
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.12288
PPP1R15B protein phosphatase 1, regulatory subunit 15B 1.12254
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 1.12254
GEM GTP binding protein overexpressed in skeletal muscle 1.12014
FKBP5 FK506 binding protein 5 1.1198
PGD phosphogluconate dehydrogenase 1.1198
CTSL cathepsin L 1.11741
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1.11639
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.11639
BMP4 bone morphogenetic protein 4 1.11536
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.11431
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.11081
IGF1 insulin-like growth factor 1 (somatomedin C) 1.11046
GPX1 glutathione peroxidase 1 1.11011
MARS methionyl-tRNA synthetase 1.10388
MSH3 mutS homolog 3 1.10388
GSTT1 glutathione S-transferase theta 1 1.10104
ATF5 activating transcription factor 5 1.09963
LZTFL1 leucine zipper transcription factor-like 1 1.09786
ITGB4 integrin, beta 4 1.09366
CALR calreticulin 1.0919
CTGF connective tissue growth factor 1.0894
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.08797
CASC5 cancer susceptibility candidate 5 1.08655
CANX calnexin 1.08407
AKAP12 A kinase (PRKA) anchor protein 12 1.08372
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.08372
H2AFX H2A histone family, member X 1.08231
IL5 interleukin 5 1.08231
IL18 interleukin 18 1.08231
GDF15 growth differentiation factor 15 1.08231
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.08091
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.08091
G6PD glucose-6-phosphate dehydrogenase 1.08091
THBS1 thrombospondin 1 1.07804
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.07732
NME7 NME/NM23 family member 7 1.07553
DPP3 dipeptidyl-peptidase 3 1.07553
PIR pirin (iron-binding nuclear protein) 1.07482
VIM vimentin 1.07269
SELL selectin L 1.07199
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.07163
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.07022
GSR glutathione reductase 1.06987
CCNG1 cyclin G1 1.06844
MCL1 myeloid cell leukemia 1 1.06588
TXN thioredoxin 1.06479
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.06261
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.0608
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.06044
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) 1.06008
GEMIN8 gem (nuclear organelle) associated protein 8 1.06008
KRT8 keratin 8, type II 1.059
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.05535
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.05535
FNDC3B fibronectin type III domain containing 3B 1.05461
MYO6 myosin VI 1.05461
RAD50 RAD50 homolog (S. cerevisiae) 1.05423
FADS1 fatty acid desaturase 1 1.05423
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.05423
AFP alpha-fetoprotein 1.05349
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.05312
CCNB1 cyclin B1 1.05089
IL1RN interleukin 1 receptor antagonist 1.04978
H1FX H1 histone family, member X 1.04978
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.04941
TUBA1A tubulin, alpha 1a 1.04868
BRCA1 breast cancer 1, early onset 1.04794
HSPA1B heat shock 70kDa protein 1B 1.04794
VCAM1 vascular cell adhesion molecule 1 1.04721
PLCG1 phospholipase C, gamma 1 1.04611
MEST mesoderm specific transcript 1.04501
CYLD cylindromatosis (turban tumor syndrome) 1.04465
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.04465
HSPA2 heat shock 70kDa protein 2 1.04314
PLG plasminogen 1.04314
GSTA1 glutathione S-transferase alpha 1 1.04201
RB1 retinoblastoma 1 1.04201
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.04014
POR P450 (cytochrome) oxidoreductase 1.03827
DTX3 deltex 3, E3 ubiquitin ligase 1.03827
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.0353
MMP13 matrix metallopeptidase 13 1.0353
CYFIP2 cytoplasmic FMR1 interacting protein 2 1.0353
SESN2 sestrin 2 1.03493
GSTM1 glutathione S-transferase mu 1 1.03419
XBP1 X-box binding protein 1 1.03197
VGF VGF nerve growth factor inducible 1.03084
DPYSL4 dihydropyrimidinase-like 4 1.03084
AKR1C2 aldo-keto reductase family 1, member C2 1.03009
SLMO2 slowmo homolog 2 (Drosophila) 1.02858
MTHFSD methenyltetrahydrofolate synthetase domain containing 1.02858
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 1.02858
TRIB3 tribbles pseudokinase 3 1.02821
TRAP1 TNF receptor-associated protein 1 1.02634
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.02485
GSTM3 glutathione S-transferase mu 3 (brain) 1.02485
MGMT O-6-methylguanine-DNA methyltransferase 1.02485
CCL3 chemokine (C-C motif) ligand 3 1.02336
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.01928
ADCK2 aarF domain containing kinase 2 1.0189
C3 complement component 3 1.01814
MXI1 MAX interactor 1, dimerization protein 1.01739
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.01663
VLDLR very low density lipoprotein receptor 1.01437
STK39 serine threonine kinase 39 1.01361
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.01324
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.01249
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.01249
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.01212
CDKN3 cyclin-dependent kinase inhibitor 3 1.01174
GPR137C G protein-coupled receptor 137C 1.01025
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 1.01025