Alzheimer's disease (late onset) Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description disease cluster belonging to disease group neurological (Genetic Association Database)
External Link https://www.ebi.ac.uk/gwas/search?query=Alzheimer's disease (late onset)
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Genes

34 genes associated with the Alzheimer's disease (late onset) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
APOC1 apolipoprotein C-I 1.41696
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.40485
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 1.35988
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.15051
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.863028
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.817441
PTK2B protein tyrosine kinase 2 beta 0.77375
EPHA1-AS1 EPHA1 antisense RNA 1 0.765464
CD2AP CD2-associated protein 0.612268
GAB2 GRB2-associated binding protein 2 0.592545
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.572839
ZCWPW1 zinc finger, CW type with PWWP domain 1 0.539238
CD33 CD33 molecule 0.499091
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.455873
FERMT2 fermitin family member 2 0.444144
CELF1 CUGBP, Elav-like family member 1 0.434785
CASS4 Cas scaffolding protein family member 4 0.389385
MEF2C-AS1 MEF2C antisense RNA 1 0.389385
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.389385
CLU clusterin 0.351407
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.351407
CELF2 CUGBP, Elav-like family member 2 0.314454
SPPL2A signal peptide peptidase like 2A 0.295129
IGH immunoglobulin heavy locus 0.295129
TRIP4 thyroid hormone receptor interactor 4 0.280662
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 0.255654
SQSTM1 sequestosome 1 0.246511
LUZP2 leucine zipper protein 2 0.238523
ATXN7L1 ataxin 7-like 1 0.220915
MPZL1 myelin protein zero-like 1 0.220915
LOC100996457 0.220915
LMOD3 leiomodin 3 (fetal) 0.165905
CDON cell adhesion associated, oncogene regulated 0.129504
PCNX pecanex homolog (Drosophila) 0.070053