Adrenoleukodystrophy Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A leukodystrophy that disrupts the breakdown of very-long-chain fatty acids resulting in progressive brain damage, failure of the adrenal glands and eventually death. (Human Disease Ontology, DOID_10588)
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Genes

16 genes associated with the Adrenoleukodystrophy phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
CBWD1 COBW domain containing 1
CD1A CD1a molecule
CD1B CD1b molecule
CD1C CD1c molecule
CD1D CD1d molecule
CD1E CD1e molecule
DHFR dihydrofolate reductase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
SOD2 superoxide dismutase 2, mitochondrial
TC2N tandem C2 domains, nuclear