Adrenocortical Carcinoma Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An adrenal cortex cancer that forms in the outer layer of tissue of the adrenal gland and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (Human Disease Ontology, DOID_3948)
Similar Terms
Downloads & Tools

Genes

22 genes associated with the Adrenocortical Carcinoma phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ATM ATM serine/threonine kinase
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
COL18A1 collagen, type XVIII, alpha 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAXX death-domain associated protein
EGFR epidermal growth factor receptor
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FRS2 fibroblast growth factor receptor substrate 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KRAS Kirsten rat sarcoma viral oncogene homolog
MED12 mediator complex subunit 12
MEN1 multiple endocrine neoplasia I
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
RB1 retinoblastoma 1
TERT telomerase reverse transcriptase
TP53 tumor protein p53
ZNRF3 zinc and ring finger 3