Adenocarcinoma of lung_Lung Tissue_GSE11969 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE11969
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Genes

600 genes differentially expressed during Adenocarcinoma of lung_Lung Tissue_GSE11969 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
TNNI2 troponin I type 2 (skeletal, fast) 2.72417
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 2.65424
ZNF397 zinc finger protein 397 2.61461
TTC24 tetratricopeptide repeat domain 24 2.57588
LRP3 low density lipoprotein receptor-related protein 3 2.54036
BAX BCL2-associated X protein 2.52132
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 2.46636
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 2.4344
U2SURP U2 snRNP-associated SURP domain containing 2.40844
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 2.39464
CFAP126 cilia and flagella associated protein 126 2.35607
HEATR6 HEAT repeat containing 6 2.34649
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.33481
TKTL2 transketolase-like 2 2.33177
ZFHX3 zinc finger homeobox 3 2.3126
GATAD1 GATA zinc finger domain containing 1 2.28884
RCOR1 REST corepressor 1 2.25491
PIAS2 protein inhibitor of activated STAT, 2 2.24308
UBE2D2 ubiquitin-conjugating enzyme E2D 2 2.24139
SLC30A6 solute carrier family 30 (zinc transporter), member 6 2.2227
VEGFA vascular endothelial growth factor A 2.22126
AIG1 androgen-induced 1 2.21603
C7ORF72 chromosome 7 open reading frame 72 2.20817
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.17451
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 2.15681
CDH20 cadherin 20, type 2 2.1537
M6PR mannose-6-phosphate receptor (cation dependent) 2.15241
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.13341
TDRKH tudor and KH domain containing 2.11459
FAIM Fas apoptotic inhibitory molecule 2.0849
LOC100130560 uncharacterized LOC100130560 2.08397
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 2.06297
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.05654
TCF20 transcription factor 20 (AR1) 2.05566
HIST1H4J histone cluster 1, H4j 2.04188
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 2.03516
CSMD1 CUB and Sushi multiple domains 1 2.01219
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.00743
ANAPC4 anaphase promoting complex subunit 4 2.00734
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 1.99579
OR2T1 olfactory receptor, family 2, subfamily T, member 1 1.98914
RASL10B RAS-like, family 10, member B 1.96499
RPS16 ribosomal protein S16 1.95669
TCN2 transcobalamin II 1.95515
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.95385
PPAP2B phosphatidic acid phosphatase type 2B 1.95238
SRSF11 serine/arginine-rich splicing factor 11 1.94758
SSPN sarcospan 1.91626
PLIN4 perilipin 4 1.89569
ITFG1 integrin alpha FG-GAP repeat containing 1 1.88647
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.88251
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 1.877
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 1.876
RNASEH2C ribonuclease H2, subunit C 1.86976
PTPRR protein tyrosine phosphatase, receptor type, R 1.8629
TRIM68 tripartite motif containing 68 1.86244
ZNF275 zinc finger protein 275 1.85756
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 1.85373
HAPLN2 hyaluronan and proteoglycan link protein 2 1.82503
PSG6 pregnancy specific beta-1-glycoprotein 6 1.82278
AFTPH aftiphilin 1.82106
FZD5 frizzled class receptor 5 1.81782
MRFAP1 Morf4 family associated protein 1 1.81413
RPL13 ribosomal protein L13 1.80702
GML glycosylphosphatidylinositol anchored molecule like 1.78577
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 1.78558
MAGEB1 melanoma antigen family B1 1.78162
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.78082
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.78074
DGUOK deoxyguanosine kinase 1.75897
TMEM248 transmembrane protein 248 1.75429
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.7528
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.73234
MRPL46 mitochondrial ribosomal protein L46 1.73169
LPIN2 lipin 2 1.72619
CCL24 chemokine (C-C motif) ligand 24 1.72546
C17ORF53 chromosome 17 open reading frame 53 1.72307
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 1.72056
INTS9 integrator complex subunit 9 1.71548
CD200 CD200 molecule 1.71294
DCTN3 dynactin 3 (p22) 1.70981
PLRG1 pleiotropic regulator 1 1.70969
ADRA1A adrenoceptor alpha 1A 1.70026
NET1 neuroepithelial cell transforming 1 1.69707
OLA1 Obg-like ATPase 1 1.69329
FECH ferrochelatase 1.68729
SMC5 structural maintenance of chromosomes 5 1.68479
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 1.67407
UNC93B1 unc-93 homolog B1 (C. elegans) 1.67356
LCORL ligand dependent nuclear receptor corepressor-like 1.67247
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.67174
ZYG11B zyg-11 family member B, cell cycle regulator 1.66362
MOSPD1 motile sperm domain containing 1 1.66136
PEX14 peroxisomal biogenesis factor 14 1.65964
PARP1 poly (ADP-ribose) polymerase 1 1.657
CAPG capping protein (actin filament), gelsolin-like 1.65053
IRX2 iroquois homeobox 2 1.6468
UQCRC1 ubiquinol-cytochrome c reductase core protein I 1.64301
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 1.64248
COL2A1 collagen, type II, alpha 1 1.62512
TMEM163 transmembrane protein 163 1.62476
MSRB3 methionine sulfoxide reductase B3 1.61711
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 1.61622
MYH2 myosin, heavy chain 2, skeletal muscle, adult 1.60831
PGPEP1 pyroglutamyl-peptidase I 1.60702
PSEN1 presenilin 1 1.60535
GPR63 G protein-coupled receptor 63 1.60528
RAB21 RAB21, member RAS oncogene family 1.59685
C1ORF27 chromosome 1 open reading frame 27 1.59321
AHCTF1 AT hook containing transcription factor 1 1.58922
ACADSB acyl-CoA dehydrogenase, short/branched chain 1.58693
UFM1 ubiquitin-fold modifier 1 1.58107
LRP2 low density lipoprotein receptor-related protein 2 1.57973
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 1.57769
TRIM39 tripartite motif containing 39 1.57733
TMEM2 transmembrane protein 2 1.56856
PCOLCE procollagen C-endopeptidase enhancer 1.56035
EEA1 early endosome antigen 1 1.56008
DCTN5 dynactin 5 (p25) 1.55165
MOGAT2 monoacylglycerol O-acyltransferase 2 1.54462
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.54405
HPSE2 heparanase 2 (inactive) 1.5417
SPC24 SPC24, NDC80 kinetochore complex component 1.53949
KIF20A kinesin family member 20A 1.53636
FRYL FRY-like 1.53624
UBE2E3 ubiquitin-conjugating enzyme E2E 3 1.5361
HMGB2 high mobility group box 2 1.5336
RIMS2 regulating synaptic membrane exocytosis 2 1.52953
TRPC3 transient receptor potential cation channel, subfamily C, member 3 1.52831
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.52764
UCN urocortin 1.52739
LGTN ligatin 1.52595
BST1 bone marrow stromal cell antigen 1 1.52447
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 1.52226
HRH3 histamine receptor H3 1.51901
CLN3 ceroid-lipofuscinosis, neuronal 3 1.51637
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 1.51619
MIB1 mindbomb E3 ubiquitin protein ligase 1 1.51535
LIMS1 LIM and senescent cell antigen-like domains 1 1.51513
JMJD1C jumonji domain containing 1C 1.51144
MEST mesoderm specific transcript 1.50857
FLRT2 fibronectin leucine rich transmembrane protein 2 1.50839
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 1.50793
REC8 REC8 meiotic recombination protein 1.50747
NPPA natriuretic peptide A 1.504
CNBP CCHC-type zinc finger, nucleic acid binding protein 1.50283
EME2 essential meiotic structure-specific endonuclease subunit 2 1.50208
SPATA13 spermatogenesis associated 13 1.50069
C20ORF181 chromosome 20 open reading frame 181 1.50045
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 1.49732
GPS1 G protein pathway suppressor 1 1.49433
GUCA1B guanylate cyclase activator 1B (retina) 1.49037
CRYBA4 crystallin, beta A4 1.48875
SNAP25 synaptosomal-associated protein, 25kDa 1.48556
PVR poliovirus receptor 1.48335
ZNF432 zinc finger protein 432 1.47759
TRPM4 transient receptor potential cation channel, subfamily M, member 4 1.47146
CD69 CD69 molecule 1.46906
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.46077
STRN striatin, calmodulin binding protein 1.45375
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.44733
ATAT1 alpha tubulin acetyltransferase 1 1.44629
ARL11 ADP-ribosylation factor-like 11 1.44488
CRHBP corticotropin releasing hormone binding protein 1.44431
TWF1 twinfilin actin binding protein 1 1.44408
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.44272
DCP1A decapping mRNA 1A 1.4383
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 1.43699
MTCH2 mitochondrial carrier 2 1.43641
TM6SF1 transmembrane 6 superfamily member 1 1.43435
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.43348
BTNL3 butyrophilin-like 3 1.43303
MRPL45 mitochondrial ribosomal protein L45 1.42889
WTAP Wilms tumor 1 associated protein 1.42803
KPNB1 karyopherin (importin) beta 1 1.42672
CD200R1 CD200 receptor 1 1.42575
PAPOLG poly(A) polymerase gamma 1.42164
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 1.42042
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.42033
DMTF1 cyclin D binding myb-like transcription factor 1 1.4151
MAP3K10 mitogen-activated protein kinase kinase kinase 10 1.41343
LOC284561 uncharacterized LOC284561 1.41278
F13B coagulation factor XIII, B polypeptide 1.41049
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 1.40918
GUCA2B guanylate cyclase activator 2B (uroguanylin) 1.40899
CNOT7 CCR4-NOT transcription complex, subunit 7 1.40893
ERCC5 excision repair cross-complementation group 5 1.4047
ATXN1L ataxin 1-like 1.40334
MAEL maelstrom spermatogenic transposon silencer 1.4032
GYG1 glycogenin 1 1.40224
ZNF729 zinc finger protein 729 1.4
WDR47 WD repeat domain 47 1.39597
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.39595
CMIP c-Maf inducing protein 1.39011
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.38799
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 1.38486
CRAT carnitine O-acetyltransferase 1.38221
ALKBH7 alkB, alkylation repair homolog 7 (E. coli) 1.38196
CCKBR cholecystokinin B receptor 1.38176
ZNF23 zinc finger protein 23 1.37768
AVPR2 arginine vasopressin receptor 2 1.37701
PRC1 protein regulator of cytokinesis 1 1.37601
KPNA7 karyopherin alpha 7 (importin alpha 8) 1.37577
ERVH48-1 endogenous retrovirus group 48, member 1 1.37545
PCNT pericentrin 1.3742
RBM15 RNA binding motif protein 15 1.37311
GNG8 guanine nucleotide binding protein (G protein), gamma 8 1.37194
RGS17 regulator of G-protein signaling 17 1.37009
DOCK9 dedicator of cytokinesis 9 1.36507
NKX2-5 NK2 homeobox 5 1.36176
ATXN7L1 ataxin 7-like 1 1.36078
KIF2A kinesin heavy chain member 2A 1.35611
TMEM185A transmembrane protein 185A 1.35524
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 1.35492
SPEG SPEG complex locus 1.35458
PDE2A phosphodiesterase 2A, cGMP-stimulated 1.35323
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 1.3513
LAPTM4B lysosomal protein transmembrane 4 beta 1.34903
CYB561D2 cytochrome b561 family, member D2 1.34859
SNX24 sorting nexin 24 1.3454
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 1.34335
GSTM2 glutathione S-transferase mu 2 (muscle) 1.34288
SORT1 sortilin 1 1.3412
C7 complement component 7 1.34036
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.33243
CINP cyclin-dependent kinase 2 interacting protein 1.33193
PYGO2 pygopus family PHD finger 2 1.33149
NIT2 nitrilase family, member 2 1.32387
RETNLB resistin like beta 1.32236
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 1.31863
DNPEP aspartyl aminopeptidase 1.31845
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.31811
MXD4 MAX dimerization protein 4 1.31729
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 1.31728
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.31688
SNRPN small nuclear ribonucleoprotein polypeptide N 1.31634
POLD2 polymerase (DNA directed), delta 2, accessory subunit 1.31626
ARF1 ADP-ribosylation factor 1 1.31308
FHOD3 formin homology 2 domain containing 3 1.31164
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 1.3113
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 1.30464
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.30297
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 1.30236
COPS7A COP9 signalosome subunit 7A 1.30208
JAM3 junctional adhesion molecule 3 1.30161
LRRC27 leucine rich repeat containing 27 1.30114
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 1.29812
RAB32 RAB32, member RAS oncogene family 1.29783
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 1.29611
OSMR oncostatin M receptor 1.29541
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 1.29342
RPN1 ribophorin I 1.29145
POU3F3 POU class 3 homeobox 3 1.29071
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.29056
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 1.28883
LARP1 La ribonucleoprotein domain family, member 1 1.28857
JUP junction plakoglobin 1.28828
DYNLL2 dynein, light chain, LC8-type 2 1.28755
IRX1 iroquois homeobox 1 1.28597
IRF6 interferon regulatory factor 6 1.2834
TTC32 tetratricopeptide repeat domain 32 1.28132
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 1.2804
PELP1 proline, glutamate and leucine rich protein 1 1.27856
GRB10 growth factor receptor-bound protein 10 1.278
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 1.27749
MIOX myo-inositol oxygenase 1.27654
MAST4 microtubule associated serine/threonine kinase family member 4 1.27587
C1ORF21 chromosome 1 open reading frame 21 1.27503
LST1 leukocyte specific transcript 1 1.27287
PDK2 pyruvate dehydrogenase kinase, isozyme 2 1.27214
SPRR1B small proline-rich protein 1B 1.26989
FAM135A family with sequence similarity 135, member A 1.2676
TRPC1 transient receptor potential cation channel, subfamily C, member 1 1.26553
ANKRD33B ankyrin repeat domain 33B 1.26546
AQP5 aquaporin 5 1.26432
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.26392
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.26065
CAPN10 calpain 10 1.25617
PNP purine nucleoside phosphorylase 1.25453
FOXC2 forkhead box C2 1.25291
TUBA3E tubulin, alpha 3e 1.2523
EBF3 early B-cell factor 3 1.25051
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1.24812
IL19 interleukin 19 1.24641
SAFB2 scaffold attachment factor B2 1.24618
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.24513
CCR3 chemokine (C-C motif) receptor 3 1.24481
FAM98A family with sequence similarity 98, member A 1.24471
CCKAR cholecystokinin A receptor 1.24467
ARID3A AT rich interactive domain 3A (BRIGHT-like) 1.2429
MCMDC2 minichromosome maintenance domain containing 2 1.24278
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.24216
TROAP trophinin associated protein 1.23995
FNDC8 fibronectin type III domain containing 8 1.23881
CKS1B CDC28 protein kinase regulatory subunit 1B 1.23783
KRT75 keratin 75, type II 1.23558
DOHH deoxyhypusine hydroxylase/monooxygenase 1.2343
MDFIC MyoD family inhibitor domain containing 1.23255
RECQL4 RecQ protein-like 4 1.22686
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 1.22683

decreased expression

Symbol Name Standardized Value
TH tyrosine hydroxylase -3.71327
KIAA0391 KIAA0391 -3.66707
TESK2 testis-specific kinase 2 -3.63259
RHBDD1 rhomboid domain containing 1 -3.58786
MMP3 matrix metallopeptidase 3 -3.58324
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -3.48423
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -3.47754
TGOLN2 trans-golgi network protein 2 -3.35487
RPL11 ribosomal protein L11 -3.28692
MEX3B mex-3 RNA binding family member B -3.20861
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 -3.1905
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -3.01486
KLHL3 kelch-like family member 3 -3.01467
REL v-rel avian reticuloendotheliosis viral oncogene homolog -2.93373
NDOR1 NADPH dependent diflavin oxidoreductase 1 -2.89496
CCNJ cyclin J -2.88447
MACROD1 MACRO domain containing 1 -2.87263
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.85692
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.83552
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -2.83284
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase -2.81744
CARD8 caspase recruitment domain family, member 8 -2.791
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 -2.76028
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -2.73111
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -2.72537
SOX7 SRY (sex determining region Y)-box 7 -2.7191
SKIL SKI-like proto-oncogene -2.67966
CHMP5 charged multivesicular body protein 5 -2.61334
UNC119 unc-119 homolog (C. elegans) -2.59812
SERF2 small EDRK-rich factor 2 -2.55312
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.5431
FBXO9 F-box protein 9 -2.53981
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit -2.53751
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -2.53592
DEDD death effector domain containing -2.51972
NCOA2 nuclear receptor coactivator 2 -2.49924
GRIK1 glutamate receptor, ionotropic, kainate 1 -2.49582
MOCS1 molybdenum cofactor synthesis 1 -2.49066
GTF2A2 general transcription factor IIA, 2, 12kDa -2.47772
HSPA1A heat shock 70kDa protein 1A -2.47599
MBTD1 mbt domain containing 1 -2.47423
THBS4 thrombospondin 4 -2.46312
GDI1 GDP dissociation inhibitor 1 -2.4493
FYCO1 FYVE and coiled-coil domain containing 1 -2.43993
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.42207
SDAD1 SDA1 domain containing 1 -2.40454
WDR4 WD repeat domain 4 -2.40165
CAST calpastatin -2.40113
CEP120 centrosomal protein 120kDa -2.39885
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -2.39167
RPL7A ribosomal protein L7a -2.38862
DCAF6 DDB1 and CUL4 associated factor 6 -2.38483
ZNF862 zinc finger protein 862 -2.378
BMP1 bone morphogenetic protein 1 -2.37675
NME7 NME/NM23 family member 7 -2.36661
DNTT DNA nucleotidylexotransferase -2.34785
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.32908
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -2.32689
URGCP upregulator of cell proliferation -2.32396
ZFP36L1 ZFP36 ring finger protein-like 1 -2.31353
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -2.30791
CNST consortin, connexin sorting protein -2.28027
DMBT1 deleted in malignant brain tumors 1 -2.27273
DGKB diacylglycerol kinase, beta 90kDa -2.27222
DPH1 diphthamide biosynthesis 1 -2.26053
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -2.25458
GSTM3 glutathione S-transferase mu 3 (brain) -2.25117
C8ORF76 chromosome 8 open reading frame 76 -2.24721
TRAF3 TNF receptor-associated factor 3 -2.24001
GATA5 GATA binding protein 5 -2.23452
ZYX zyxin -2.21979
OSBPL8 oxysterol binding protein-like 8 -2.21705
NRIP3 nuclear receptor interacting protein 3 -2.20409
ATAD2B ATPase family, AAA domain containing 2B -2.19296
CECR5 cat eye syndrome chromosome region, candidate 5 -2.1906
SLC17A4 solute carrier family 17, member 4 -2.19039
MAP1B microtubule-associated protein 1B -2.17983
PCSK6 proprotein convertase subtilisin/kexin type 6 -2.17919
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -2.16725
CDT1 chromatin licensing and DNA replication factor 1 -2.16675
TNNT3 troponin T type 3 (skeletal, fast) -2.1616
TMTC3 transmembrane and tetratricopeptide repeat containing 3 -2.15897
PARD6A par-6 family cell polarity regulator alpha -2.15878
C11ORF31 chromosome 11 open reading frame 31 -2.15605
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -2.15341
HIGD1A HIG1 hypoxia inducible domain family, member 1A -2.14865
POU5F1P3 POU class 5 homeobox 1 pseudogene 3 -2.12158
ZSWIM7 zinc finger, SWIM-type containing 7 -2.10924
KLRC3 killer cell lectin-like receptor subfamily C, member 3 -2.10909
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -2.10762
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.07801
KLF10 Kruppel-like factor 10 -2.07408
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -2.07159
KCTD4 potassium channel tetramerization domain containing 4 -2.06065
MBTPS2 membrane-bound transcription factor peptidase, site 2 -2.06056
TNIP3 TNFAIP3 interacting protein 3 -2.05485
ELAVL1 ELAV like RNA binding protein 1 -2.05192
SH3BGR SH3 domain binding glutamate-rich protein -2.0513
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 -2.0487
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 -2.04676
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 -2.04063
DOK4 docking protein 4 -2.0357
CD70 CD70 molecule -2.02876
CYB5R1 cytochrome b5 reductase 1 -2.02663
OXLD1 oxidoreductase-like domain containing 1 -2.02293
HES2 hes family bHLH transcription factor 2 -2.01158
SECISBP2 SECIS binding protein 2 -2.00225
HOXD13 homeobox D13 -2.00175
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -1.98723
ITPKC inositol-trisphosphate 3-kinase C -1.97992
FCAMR Fc receptor, IgA, IgM, high affinity -1.97774
SH3GLB1 SH3-domain GRB2-like endophilin B1 -1.96709
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -1.96699
SLAMF7 SLAM family member 7 -1.9668
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -1.96228
UBQLN2 ubiquilin 2 -1.95433
DUSP19 dual specificity phosphatase 19 -1.94845
EIF3K eukaryotic translation initiation factor 3, subunit K -1.94627
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -1.94612
TUSC3 tumor suppressor candidate 3 -1.94608
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -1.9455
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -1.92919
TBC1D12 TBC1 domain family, member 12 -1.92319
NMD3 NMD3 ribosome export adaptor -1.91577
MTAP methylthioadenosine phosphorylase -1.91402
LINC00294 long intergenic non-protein coding RNA 294 -1.91402
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -1.90716
AK2 adenylate kinase 2 -1.90658
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -1.90642
SPRED2 sprouty-related, EVH1 domain containing 2 -1.90099
EBP emopamil binding protein (sterol isomerase) -1.89747
EPS8L1 EPS8-like 1 -1.8974
BPIFB1 BPI fold containing family B, member 1 -1.89505
GZMM granzyme M (lymphocyte met-ase 1) -1.88889
PA2G4 proliferation-associated 2G4, 38kDa -1.88704
SOX3 SRY (sex determining region Y)-box 3 -1.88554
GMEB2 glucocorticoid modulatory element binding protein 2 -1.88269
STAG3 stromal antigen 3 -1.87136
POLG polymerase (DNA directed), gamma -1.86699
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -1.86652
UBE2M ubiquitin-conjugating enzyme E2M -1.86496
EML5 echinoderm microtubule associated protein like 5 -1.86259
NKX2-1 NK2 homeobox 1 -1.85309
SH3GL3 SH3-domain GRB2-like 3 -1.83725
ZSWIM5 zinc finger, SWIM-type containing 5 -1.83564
BCLAF1 BCL2-associated transcription factor 1 -1.82865
AARSD1 alanyl-tRNA synthetase domain containing 1 -1.8224
DPPA5 developmental pluripotency associated 5 -1.82139
COPS6 COP9 signalosome subunit 6 -1.82064
ZNF576 zinc finger protein 576 -1.81891
LAP3 leucine aminopeptidase 3 -1.81217
HECW1-IT1 HECW1 intronic transcript 1 -1.80931
RAB27B RAB27B, member RAS oncogene family -1.80706
DOCK11 dedicator of cytokinesis 11 -1.79831
CYTH3 cytohesin 3 -1.79276
FGD1 FYVE, RhoGEF and PH domain containing 1 -1.78938
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.78904
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 -1.7873
FLRT1 fibronectin leucine rich transmembrane protein 1 -1.78593
USP46 ubiquitin specific peptidase 46 -1.78508
WDR41 WD repeat domain 41 -1.77834
PLA1A phospholipase A1 member A -1.77761
GLIPR1 GLI pathogenesis-related 1 -1.76646
HYLS1 hydrolethalus syndrome 1 -1.76088
CPN2 carboxypeptidase N, polypeptide 2 -1.76005
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.75976
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -1.75212
LRRC4B leucine rich repeat containing 4B -1.75092
TMEM39B transmembrane protein 39B -1.75029
CHRD chordin -1.74572
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -1.74109
PDLIM1 PDZ and LIM domain 1 -1.74035
ERLIN1 ER lipid raft associated 1 -1.7353
PDLIM5 PDZ and LIM domain 5 -1.73116
TGFBI transforming growth factor, beta-induced, 68kDa -1.72977
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -1.72849
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -1.72404
TGFB3 transforming growth factor, beta 3 -1.72294
RHAG Rh-associated glycoprotein -1.72157
TNS1 tensin 1 -1.72001
SMNDC1 survival motor neuron domain containing 1 -1.71998
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 -1.71934
CCNT2 cyclin T2 -1.71321
BBS9 Bardet-Biedl syndrome 9 -1.71072
RHOH ras homolog family member H -1.70051
MAL mal, T-cell differentiation protein -1.69988
LMNB1 lamin B1 -1.69166
C9ORF156 chromosome 9 open reading frame 156 -1.68977
CEP72 centrosomal protein 72kDa -1.68604
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -1.68235
SF3B5 splicing factor 3b, subunit 5, 10kDa -1.67624
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -1.67365
ACY3 aminoacylase 3 -1.67315
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -1.66974
VCX3A variable charge, X-linked 3A -1.66921
PUF60 poly-U binding splicing factor 60KDa -1.66906
DCAF4 DDB1 and CUL4 associated factor 4 -1.66449
LCLAT1 lysocardiolipin acyltransferase 1 -1.65833
FGF2 fibroblast growth factor 2 (basic) -1.65806
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H -1.6566
ATXN10 ataxin 10 -1.65547
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -1.65344
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.64904
GBP2 guanylate binding protein 2, interferon-inducible -1.6483
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -1.64749
DUSP23 dual specificity phosphatase 23 -1.63973
SCN3B sodium channel, voltage gated, type III beta subunit -1.63765
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -1.63522
MATN1-AS1 MATN1 antisense RNA 1 -1.63484
EZR ezrin -1.62806
SON SON DNA binding protein -1.62784
RPL5 ribosomal protein L5 -1.62675
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -1.62625
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 -1.61495
KIF1A kinesin family member 1A -1.61477
UXS1 UDP-glucuronate decarboxylase 1 -1.6103
PAPD4 PAP associated domain containing 4 -1.60827
TP53RK TP53 regulating kinase -1.60493
ASXL3 additional sex combs like transcriptional regulator 3 -1.60456
INSIG2 insulin induced gene 2 -1.60273
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 -1.60103
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 -1.59918
SLA Src-like-adaptor -1.59911
MORC4 MORC family CW-type zinc finger 4 -1.59704
MMP26 matrix metallopeptidase 26 -1.59428
CDC25B cell division cycle 25B -1.59133
TUBG1 tubulin, gamma 1 -1.59081
NAP1L1 nucleosome assembly protein 1-like 1 -1.58447
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -1.58364
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -1.58245
GLI3 GLI family zinc finger 3 -1.58235
C2ORF40 chromosome 2 open reading frame 40 -1.58235
FGFR4 fibroblast growth factor receptor 4 -1.57989
CYB5R4 cytochrome b5 reductase 4 -1.57846
PDE1A phosphodiesterase 1A, calmodulin-dependent -1.57759
TRIM14 tripartite motif containing 14 -1.57689
QKI QKI, KH domain containing, RNA binding -1.57658
THEM5 thioesterase superfamily member 5 -1.57612
CIB2 calcium and integrin binding family member 2 -1.57553
WASF3 WAS protein family, member 3 -1.57437
BRD3 bromodomain containing 3 -1.57087
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -1.56454
NGDN neuroguidin, EIF4E binding protein -1.56318
KRTAP2-4 keratin associated protein 2-4 -1.56283
ZDHHC17 zinc finger, DHHC-type containing 17 -1.56097
AFAP1 actin filament associated protein 1 -1.55743
FIGNL1 fidgetin-like 1 -1.55564
NR2E1 nuclear receptor subfamily 2, group E, member 1 -1.55468
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.55196
PHEX phosphate regulating endopeptidase homolog, X-linked -1.55001
GLMP glycosylated lysosomal membrane protein -1.54996
ZFP91 ZFP91 zinc finger protein -1.54792
RIT2 Ras-like without CAAX 2 -1.5473
EPHA1 EPH receptor A1 -1.54649
TGFBR1 transforming growth factor, beta receptor 1 -1.54437
PEX12 peroxisomal biogenesis factor 12 -1.5439
COL4A6 collagen, type IV, alpha 6 -1.54238
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -1.53487
B3GAT1 beta-1,3-glucuronyltransferase 1 -1.53441
EPHA4 EPH receptor A4 -1.5334
KDM3B lysine (K)-specific demethylase 3B -1.53287
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 -1.52904
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -1.52898
GDNF glial cell derived neurotrophic factor -1.52774
LDB3 LIM domain binding 3 -1.52726
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -1.52524
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 -1.52518
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -1.52426
H2AFY H2A histone family, member Y -1.52206
RNF14 ring finger protein 14 -1.51843
PDCD6 programmed cell death 6 -1.51771
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -1.51372
HPSE heparanase -1.51346
LOC286059 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain pseudogene -1.51307
LIPH lipase, member H -1.51282
BCAR1 breast cancer anti-estrogen resistance 1 -1.51156
IL2RG interleukin 2 receptor, gamma -1.50919
APH1B APH1B gamma secretase subunit -1.50324
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -1.49852
ACTN3 actinin, alpha 3 (gene/pseudogene) -1.49826
MRPL20 mitochondrial ribosomal protein L20 -1.49708
CSDE1 cold shock domain containing E1, RNA-binding -1.49453
CREBBP CREB binding protein -1.49435
C6ORF106 chromosome 6 open reading frame 106 -1.49332
TCAP titin-cap -1.49066
ANXA4 annexin A4 -1.49062
AREG amphiregulin -1.49029
PROS1 protein S (alpha) -1.4857
BRAP BRCA1 associated protein -1.48295
MRPS36 mitochondrial ribosomal protein S36 -1.48203
ADHFE1 alcohol dehydrogenase, iron containing, 1 -1.47989
BASP1 brain abundant, membrane attached signal protein 1 -1.47935
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a -1.47643
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -1.47582
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -1.47516
DHODH dihydroorotate dehydrogenase (quinone) -1.47304
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -1.4728
SETDB1 SET domain, bifurcated 1 -1.47117
KDM4C lysine (K)-specific demethylase 4C -1.46993
NUP93 nucleoporin 93kDa -1.46519