Adaptive Immune System Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1280218
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Genes

648 proteins participating in the Adaptive Immune System pathway from the Reactome Pathways dataset.

Symbol Name
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMICA1 adhesion molecule, interacts with CXADR antigen 1
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC13 anaphase promoting complex subunit 13
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARF1 ADP-ribosylation factor 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASB1 ankyrin repeat and SOCS box containing 1
ASB10 ankyrin repeat and SOCS box containing 10
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASB12 ankyrin repeat and SOCS box containing 12
ASB13 ankyrin repeat and SOCS box containing 13
ASB14 ankyrin repeat and SOCS box containing 14
ASB15 ankyrin repeat and SOCS box containing 15
ASB16 ankyrin repeat and SOCS box containing 16
ASB17 ankyrin repeat and SOCS box containing 17
ASB18 ankyrin repeat and SOCS box containing 18
ASB2 ankyrin repeat and SOCS box containing 2
ASB3 ankyrin repeat and SOCS box containing 3
ASB4 ankyrin repeat and SOCS box containing 4
ASB5 ankyrin repeat and SOCS box containing 5
ASB6 ankyrin repeat and SOCS box containing 6
ASB7 ankyrin repeat and SOCS box containing 7
ASB8 ankyrin repeat and SOCS box containing 8
ASB9 ankyrin repeat and SOCS box containing 9
ATG7 autophagy related 7
B2M beta-2-microglobulin
BAD BCL2-associated agonist of cell death
BCL10 B-cell CLL/lymphoma 10
BLK BLK proto-oncogene, Src family tyrosine kinase
BLMH bleomycin hydrolase
BLNK B-cell linker
BTC betacellulin
BTK Bruton agammaglobulinemia tyrosine kinase
BTLA B and T lymphocyte associated
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C3 complement component 3
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALR calreticulin
CANX calnexin
CARD11 caspase recruitment domain family, member 11
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD160 CD160 molecule
CD19 CD19 molecule
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD207 CD207 molecule, langerin
CD226 CD226 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD81 CD81 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CD96 CD96 molecule
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC34 cell division cycle 34
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CENPE centromere protein E, 312kDa
CHUK conserved helix-loop-helix ubiquitous kinase
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
CREB1 cAMP responsive element binding protein 1
CRTAM cytotoxic and regulatory T cell molecule
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSA cathepsin A
CTSB cathepsin B
CTSC cathepsin C
CTSD cathepsin D
CTSE cathepsin E
CTSF cathepsin F
CTSH cathepsin H
CTSK cathepsin K
CTSL cathepsin L
CTSO cathepsin O
CTSS cathepsin S
CTSV cathepsin V
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL5 cullin 5
CUL7 cullin 7
CXADR coxsackie virus and adenovirus receptor
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DCTN4 dynactin 4 (p62)
DCTN5 dynactin 5 (p25)
DCTN6 dynactin 6
DET1 de-etiolated homolog 1 (Arabidopsis)
DNM1 dynamin 1
DNM2 dynamin 2
DNM3 dynamin 3
DTX3L deltex 3 like, E3 ubiquitin ligase
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
DZIP3 DAZ interacting zinc finger protein 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ENAH enabled homolog (Drosophila)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
EVL Enah/Vasp-like
FBXO17 F-box protein 17
FBXO2 F-box protein 2
FBXO27 F-box protein 27
FBXO3 F-box protein 3
FBXO4 F-box protein 4
FBXO44 F-box protein 44
FBXO6 F-box protein 6
FBXW11 F-box and WD repeat domain containing 11
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FRS2 fibroblast growth factor receptor substrate 2
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAB1 GRB2-associated binding protein 1
GAN gigaxonin
GLYCAM1 glycosylation dependent cell adhesion molecule 1 (pseudogene)
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HBEGF heparin-binding EGF-like growth factor
HCST hematopoietic cell signal transducer
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFI30 interferon, gamma-inducible protein 30
IFITM1 interferon induced transmembrane protein 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGHV7-81 immunoglobulin heavy variable 7-81 (non-functional)
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IGLC7 immunoglobulin lambda constant 7
IGLV1-36 immunoglobulin lambda variable 1-36
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV1-44 immunoglobulin lambda variable 1-44
IGLV10-54 immunoglobulin lambda variable 10-54
IGLV11-55 immunoglobulin lambda variable 11-55 (non-functional)
IGLV2-11 immunoglobulin lambda variable 2-11
IGLV2-18 immunoglobulin lambda variable 2-18
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV2-33 immunoglobulin lambda variable 2-33 (non-functional)
IGLV3-12 immunoglobulin lambda variable 3-12
IGLV3-16 immunoglobulin lambda variable 3-16
IGLV3-22 immunoglobulin lambda variable 3-22 (gene/pseudogene)
IGLV3-25 immunoglobulin lambda variable 3-25
IGLV3-27 immunoglobulin lambda variable 3-27
IGLV4-3 immunoglobulin lambda variable 4-3
IGLV4-60 immunoglobulin lambda variable 4-60
IGLV4-69 immunoglobulin lambda variable 4-69
IGLV5-37 immunoglobulin lambda variable 5-37
IGLV5-45 immunoglobulin lambda variable 5-45
IGLV7-43 immunoglobulin lambda variable 7-43
IGLV7-46 immunoglobulin lambda variable 7-46 (gene/pseudogene)
IGLV8-61 immunoglobulin lambda variable 8-61
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITCH itchy E3 ubiquitin protein ligase
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB5 integrin, beta 5
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KEAP1 kelch-like ECH-associated protein 1
KIF11 kinesin family member 11
KIF15 kinesin family member 15
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KIF22 kinesin family member 22
KIF23 kinesin family member 23
KIF26A kinesin family member 26A
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIF2C kinesin family member 2C
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KIF3C kinesin family member 3C
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
KIF5A kinesin family member 5A
KIF5B kinesin family member 5B
KIF5C kinesin family member 5C
KIFAP3 kinesin-associated protein 3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLB klotho beta
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KLC3 kinesin light chain 3
KLC4 kinesin light chain 4
KLHL13 kelch-like family member 13
KLHL20 kelch-like family member 20
KLHL21 kelch-like family member 21
KLHL9 kelch-like family member 9
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LGMN legumain
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LNPEP leucyl/cystinyl aminopeptidase
LRR1 leucine rich repeat protein 1
LRRC41 leucine rich repeat containing 41
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MALT1 MALT1 paracaspase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIR26A1 microRNA 26a-1
MIR26A2 microRNA 26a-2
MKRN1 makorin ring finger protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MOV10 Mov10 RISC complex RNA helicase
MRC1 mannose receptor, C type 1
MRC2 mannose receptor, C type 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCK1 NCK adaptor protein 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NPEPPS aminopeptidase puromycin sensitive
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG3 neuregulin 3
NRG4 neuregulin 4
ORAI1 ORAI calcium release-activated calcium modulator 1
OSBPL1A oxysterol binding protein-like 1A
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA3 protein disulfide isomerase family A, member 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCB protein kinase C, beta
PRKCQ protein kinase C, theta
PRKG1 protein kinase, cGMP-dependent, type I
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PVR poliovirus receptor
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB7A RAB7A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAET1E retinoic acid early transcript 1E
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RAP1GAP2 RAP1 GTPase activating protein 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RICTOR RPTOR independent companion of MTOR, complex 2
RILP Rab interacting lysosomal protein
RIPK2 receptor-interacting serine-threonine kinase 2
RNF111 ring finger protein 111
RNF123 ring finger protein 123
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF144B ring finger protein 144B
RNF182 ring finger protein 182
RNF19B ring finger protein 19B
RNF220 ring finger protein 220
RNF25 ring finger protein 25
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RPS27A ribosomal protein S27a
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SAR1B secretion associated, Ras related GTPase 1B
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SELL selectin L
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIPA1 signal-induced proliferation-associated 1
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SPTBN2 spectrin, beta, non-erythrocytic 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
STIM1 stromal interaction molecule 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYK spleen tyrosine kinase
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
THEM4 thioesterase superfamily member 4
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNRC6A trinucleotide repeat containing 6A
TNRC6B trinucleotide repeat containing 6B
TNRC6C trinucleotide repeat containing 6C
TPP2 tripeptidyl peptidase II
TRAC T cell receptor alpha constant
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAT1 T cell receptor associated transmembrane adaptor 1
TRBC1 T cell receptor beta constant 1
TRBV12-3 T cell receptor beta variable 12-3
TRIB3 tribbles pseudokinase 3
TRIM11 tripartite motif containing 11
TRIM21 tripartite motif containing 21
TRIM32 tripartite motif containing 32
TRIM36 tripartite motif containing 36
TRIM37 tripartite motif containing 37
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIM9 tripartite motif containing 9
TRIP12 thyroid hormone receptor interactor 12
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSC2 tuberous sclerosis 2
TYROBP TYRO protein tyrosine kinase binding protein
UBA1 ubiquitin-like modifier activating enzyme 1
UBA3 ubiquitin-like modifier activating enzyme 3
UBA5 ubiquitin-like modifier activating enzyme 5
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA6 ubiquitin-like modifier activating enzyme 6
UBA7 ubiquitin-like modifier activating enzyme 7
UBB ubiquitin B
UBC ubiquitin C
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2M ubiquitin-conjugating enzyme E2M
UBE2N ubiquitin-conjugating enzyme E2N
UBE2O ubiquitin-conjugating enzyme E2O
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2S ubiquitin-conjugating enzyme E2S
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE2Z ubiquitin-conjugating enzyme E2Z
UBE3A ubiquitin protein ligase E3A
UBE3B ubiquitin protein ligase E3B
UBE3C ubiquitin protein ligase E3C
UBE4A ubiquitination factor E4A
UBOX5 U-box domain containing 5
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR4 ubiquitin protein ligase E3 component n-recognin 4
ULBP1 UL16 binding protein 1
ULBP3 UL16 binding protein 3
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPRBP Vpr (HIV-1) binding protein
WAS Wiskott-Aldrich syndrome
WSB1 WD repeat and SOCS box containing 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB16 zinc finger and BTB domain containing 16