Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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Genes

459 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACACB acetyl-CoA carboxylase beta
ACAT2 acetyl-CoA acetyltransferase 2
ACTC1 actin, alpha, cardiac muscle 1
ADAM17 ADAM metallopeptidase domain 17
ADAM22 ADAM metallopeptidase domain 22
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADCY5 adenylate cyclase 5
ADGRD2 adhesion G protein-coupled receptor D2
ADGRE5 adhesion G protein-coupled receptor E5
ADGRF3 adhesion G protein-coupled receptor F3
ADGRL3 adhesion G protein-coupled receptor L3
ADM2 adrenomedullin 2
ADRB3 adrenoceptor beta 3
ALCAM activated leukocyte cell adhesion molecule
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12
ANGPT4 angiopoietin 4
ANXA2P3 annexin A2 pseudogene 3
ANXA8 annexin A8
ANXA8L1 annexin A8-like 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP3 aquaporin 3 (Gill blood group)
ARHGAP25 Rho GTPase activating protein 25
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMT1 acidic residue methyltransferase 1
ARSB arylsulfatase B
ASF1B anti-silencing function 1B histone chaperone
ASS1 argininosuccinate synthase 1
ATG13 autophagy related 13
ATP11A ATPase, class VI, type 11A
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATRIP ATR interacting protein
AZI2 5-azacytidine induced 2
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BCO2 beta-carotene oxygenase 2
BEND6 BEN domain containing 6
BMS1P5 BMS1 ribosome biogenesis factor pseudogene 5
BPESC1 blepharophimosis, epicanthus inversus and ptosis, candidate 1 (non-protein coding)
BTNL3 butyrophilin-like 3
BTNL8 butyrophilin-like 8
BTNL9 butyrophilin-like 9
C17ORF53 chromosome 17 open reading frame 53
C1ORF115 chromosome 1 open reading frame 115
C1ORF185 chromosome 1 open reading frame 185
C1ORF216 chromosome 1 open reading frame 216
C4ORF19 chromosome 4 open reading frame 19
C5ORF34 chromosome 5 open reading frame 34
C9ORF135 chromosome 9 open reading frame 135
CA6 carbonic anhydrase VI
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CALML6 calmodulin-like 6
CALR calreticulin
CALU calumenin
CARNS1 carnosine synthase 1
CCDC170 coiled-coil domain containing 170
CCDC77 coiled-coil domain containing 77
CCL20 chemokine (C-C motif) ligand 20
CCNA1 cyclin A1
CCNE2 cyclin E2
CCR6 chemokine (C-C motif) receptor 6
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD164L2 CD164 sialomucin-like 2
CD2 CD2 molecule
CD276 CD276 molecule
CD9 CD9 molecule
CD96 CD96 molecule
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDCA5 cell division cycle associated 5
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPO centromere protein O
CENPU centromere protein U
CEP19 centrosomal protein 19kDa
CFH complement factor H
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLEC5A C-type lectin domain family 5, member A
CLSPN claspin
CLTCL1 clathrin, heavy chain-like 1
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNGA4 cyclic nucleotide gated channel alpha 4
CNTROB centrobin, centrosomal BRCA2 interacting protein
COCH cochlin
COPG1 coatomer protein complex, subunit gamma 1
CPD carboxypeptidase D
CPSF4L cleavage and polyadenylation specific factor 4-like
CRACR2B calcium release activated channel regulator 2B
CRYGN crystallin, gamma N
CRYZ crystallin, zeta (quinone reductase)
CSNK1G1 casein kinase 1, gamma 1
CSTA cystatin A (stefin A)
CTSC cathepsin C
CXORF38 chromosome X open reading frame 38
CXORF58 chromosome X open reading frame 58
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX12P DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
DGKD diacylglycerol kinase, delta 130kDa
DHCR24 24-dehydrocholesterol reductase
DHRS7 dehydrogenase/reductase (SDR family) member 7
DIO3 deiodinase, iodothyronine, type III
DMC1 DNA meiotic recombinase 1
DNM1 dynamin 1
DOC2B double C2-like domains, beta
DONSON downstream neighbor of SON
DSC3 desmocollin 3
DSE dermatan sulfate epimerase
DSN1 DSN1, MIS12 kinetochore complex component
DTYMK deoxythymidylate kinase (thymidylate kinase)
DUSP3 dual specificity phosphatase 3
E2F1 E2F transcription factor 1
E2F7 E2F transcription factor 7
E2F8 E2F transcription factor 8
EBF3 early B-cell factor 3
EBP emopamil binding protein (sterol isomerase)
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
ECT2 epithelial cell transforming 2
EFCAB11 EF-hand calcium binding domain 11
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3C eukaryotic translation initiation factor 3, subunit C
ELOVL3 ELOVL fatty acid elongase 3
EME1 essential meiotic structure-specific endonuclease 1
EPCAM epithelial cell adhesion molecule
EPDR1 ependymin related 1
EPHB4 EPH receptor B4
EPT1 ethanolaminephosphotransferase 1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESYT1 extended synaptotagmin-like protein 1
EXO1 exonuclease 1
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
FABP2 fatty acid binding protein 2, intestinal
FAM114A1 family with sequence similarity 114, member A1
FAM124A family with sequence similarity 124A
FAM134B family with sequence similarity 134, member B
FAM136BP family with sequence similarity 136, member B, pseudogene
FAM170A family with sequence similarity 170, member A
FAM212B family with sequence similarity 212, member B
FAM21A family with sequence similarity 21, member A
FAM27B family with sequence similarity 27, member B
FAM45A family with sequence similarity 45, member A
FAM45B family with sequence similarity 45, member A pseudogene
FAM47E family with sequence similarity 47, member E
FAM57B family with sequence similarity 57, member B
FANCD2 Fanconi anemia, complementation group D2
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FAS Fas cell surface death receptor
FBLN1 fibulin 1
FBN2 fibrillin 2
FGFR3 fibroblast growth factor receptor 3
FKBP5 FK506 binding protein 5
FNTB farnesyltransferase, CAAX box, beta
FOXM1 forkhead box M1
FXYD1 FXYD domain containing ion transport regulator 1
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCH1 GTP cyclohydrolase 1
GGT5 gamma-glutamyltransferase 5
GINS4 GINS complex subunit 4 (Sld5 homolog)
GJC1 gap junction protein, gamma 1, 45kDa
GK3P glycerol kinase 3 pseudogene
GLI2 GLI family zinc finger 2
GLMP glycosylated lysosomal membrane protein
GLT8D1 glycosyltransferase 8 domain containing 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPR143 G protein-coupled receptor 143
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GRB10 growth factor receptor-bound protein 10
GSG1L GSG1-like
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAPLN4 hyaluronan and proteoglycan link protein 4
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HRASLS5 HRAS-like suppressor family, member 5
HRH2 histamine receptor H2
HSPA4L heat shock 70kDa protein 4-like
HTATSF1 HIV-1 Tat specific factor 1
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1RAP interleukin 1 receptor accessory protein
ING5 inhibitor of growth family, member 5
INSR insulin receptor
JAG1 jagged 1
JDP2 Jun dimerization protein 2
JPH1 junctophilin 1
KCTD2 potassium channel tetramerization domain containing 2
KIAA0195 KIAA0195
KIAA0319L KIAA0319-like
KIF24 kinesin family member 24
KLHL2 kelch-like family member 2
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRTAP17-1 keratin associated protein 17-1
KRTAP4-3 keratin associated protein 4-3
LAX1 lymphocyte transmembrane adaptor 1
LCE1E late cornified envelope 1E
LGALS12 lectin, galactoside-binding, soluble, 12
LGALS7 lectin, galactoside-binding, soluble, 7
LINC00319 long intergenic non-protein coding RNA 319
LINC00483 long intergenic non-protein coding RNA 483
LINC01554 long intergenic non-protein coding RNA 1554
LOC100287704 uncharacterized LOC100287704
LOC148709 actin pseudogene
LOC284023 uncharacterized LOC284023
LPO lactoperoxidase
LRRC17 leucine rich repeat containing 17
LY6D lymphocyte antigen 6 complex, locus D
LYZL4 lysozyme-like 4
MAGED1 melanoma antigen family D1
MAOA monoamine oxidase A
MAP1A microtubule-associated protein 1A
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP4 microtubule-associated protein 4
MARK3 MAP/microtubule affinity-regulating kinase 3
MASTL microtubule associated serine/threonine kinase-like
MCAM melanoma cell adhesion molecule
MCM10 minichromosome maintenance complex component 10
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MELK maternal embryonic leucine zipper kinase
MFGE8 milk fat globule-EGF factor 8 protein
MID2 midline 2
MKKS McKusick-Kaufman syndrome
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKRN2 makorin ring finger protein 2
MLNR motilin receptor
MMP19 matrix metallopeptidase 19
MORN3 MORN repeat containing 3
MPO myeloperoxidase
MRGPRE MAS-related GPR, member E
MSLNL mesothelin-like
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MXRA7 matrix-remodelling associated 7
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYO1B myosin IB
MYRF myelin regulatory factor
N4BP2L1 NEDD4 binding protein 2-like 1
NAAA N-acylethanolamine acid amidase
NABP1 nucleic acid binding protein 1
NCAPG2 non-SMC condensin II complex, subunit G2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFE2L1 nuclear factor, erythroid 2-like 1
NHLH2 nescient helix loop helix 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NLRP10 NLR family, pyrin domain containing 10
NLRP2 NLR family, pyrin domain containing 2
NOMO3 NODAL modulator 3
NOTCH3 notch 3
NPY4R neuropeptide Y receptor Y4
NRSN2 neurensin 2
NTAN1 N-terminal asparagine amidase
NTF3 neurotrophin 3
OCSTAMP osteoclast stimulatory transmembrane protein
OGDHL oxoglutarate dehydrogenase-like
OPN4 opsin 4
OR13A1 olfactory receptor, family 13, subfamily A, member 1
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR4D9 olfactory receptor, family 4, subfamily D, member 9
OR5B2 olfactory receptor, family 5, subfamily B, member 2
OR9A4 olfactory receptor, family 9, subfamily A, member 4
ORAI1 ORAI calcium release-activated calcium modulator 1
ORC6 origin recognition complex, subunit 6
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PC pyruvate carboxylase
PCDHA1 protocadherin alpha 1
PCDHA10 protocadherin alpha 10
PCDHA13 protocadherin alpha 13
PCDHA2 protocadherin alpha 2
PCDHA3 protocadherin alpha 3
PCDHA9 protocadherin alpha 9
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHAC2 protocadherin alpha subfamily C, 2
PCYOX1 prenylcysteine oxidase 1
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDIA4 protein disulfide isomerase family A, member 4
PDIA5 protein disulfide isomerase family A, member 5
PGBD5 piggyBac transposable element derived 5
PGD phosphogluconate dehydrogenase
PHF13 PHD finger protein 13
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLA2G2C phospholipase A2, group IIC
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLXNA2 plexin A2
PLXNA3 plexin A3
PMFBP1 polyamine modulated factor 1 binding protein 1
PMP22 peripheral myelin protein 22
POFUT1 protein O-fucosyltransferase 1
POTEE POTE ankyrin domain family, member E
PPARG peroxisome proliferator-activated receptor gamma
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRKCE protein kinase C, epsilon
PRODH proline dehydrogenase (oxidase) 1
PROL1 proline rich, lacrimal 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS35 protease, serine, 35
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMC3IP PSMC3 interacting protein
PTCH1 patched 1
PVR poliovirus receptor
PVRL4 poliovirus receptor-related 4
PXT1 peroxisomal, testis specific 1
RAB17 RAB17, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RACGAP1 Rac GTPase activating protein 1
RAD51 RAD51 recombinase
RAD54L RAD54-like (S. cerevisiae)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAP2A RAP2A, member of RAS oncogene family
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RDH10 retinol dehydrogenase 10 (all-trans)
RETN resistin
RFTN1 raftlin, lipid raft linker 1
RGSL1 regulator of G-protein signaling like 1
RIBC2 RIB43A domain with coiled-coils 2
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF146 ring finger protein 146
RNF19B ring finger protein 19B
ROGDI rogdi homolog (Drosophila)
ROPN1L rhophilin associated tail protein 1-like
RPN1 ribophorin I
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRM2 ribonucleotide reductase M2
S100B S100 calcium binding protein B
SAE1 SUMO1 activating enzyme subunit 1
SAG S-antigen; retina and pineal gland (arrestin)
SAP30 Sin3A-associated protein, 30kDa
SCRG1 stimulator of chondrogenesis 1
SDC4 syndecan 4
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
SEC31A SEC31 homolog A (S. cerevisiae)
SEPT12 septin 12
SESN2 sestrin 2
SFRP4 secreted frizzled-related protein 4
SH3PXD2B SH3 and PX domains 2B
SHCBP1 SHC SH2-domain binding protein 1
SIAE sialic acid acetylesterase
SIMC1 SUMO-interacting motifs containing 1
SIX3 SIX homeobox 3
SKA3 spindle and kinetochore associated complex subunit 3
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC39A11 solute carrier family 39, member 11
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLFN13 schlafen family member 13
SLPI secretory leukocyte peptidase inhibitor
SLX4 SLX4 structure-specific endonuclease subunit
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNORA31 small nucleolar RNA, H/ACA box 31
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA58 small nucleolar RNA, H/ACA box 58
SNORA59B small nucleolar RNA, H/ACA box 59B
SNORA71D small nucleolar RNA, H/ACA box 71D
SNORA80A small nucleolar RNA, H/ACA box 80A
SNORD67 small nucleolar RNA, C/D box 67
SPATA18 spermatogenesis associated 18
SPDYE2 speedy/RINGO cell cycle regulator family member E2
SPON2 spondin 2, extracellular matrix protein
SSTR2 somatostatin receptor 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STAT4 signal transducer and activator of transcription 4
STIL SCL/TAL1 interrupting locus
STPG1 sperm-tail PG-rich repeat containing 1
STRN3 striatin, calmodulin binding protein 3
STS steroid sulfatase (microsomal), isozyme S
STX2 syntaxin 2
SYN1 synapsin I
SYT5 synaptotagmin V
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TARP TCR gamma alternate reading frame protein
TBC1D15 TBC1 domain family, member 15
TBC1D24 TBC1 domain family, member 24
TBC1D2B TBC1 domain family, member 2B
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TBL1X transducin (beta)-like 1X-linked
TBX20 T-box 20
TCEAL6 transcription elongation factor A (SII)-like 6
TCF19 transcription factor 19
TCN2 transcobalamin II
TDRD9 tudor domain containing 9
TECPR2 tectonin beta-propeller repeat containing 2
TEKT1 tektin 1
TEPP testis, prostate and placenta expressed
TEX38 testis expressed 38
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TGFA transforming growth factor, alpha
THRA thyroid hormone receptor, alpha
TM6SF1 transmembrane 6 superfamily member 1
TMEM164 transmembrane protein 164
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TP53BP2 tumor protein p53 binding protein 2
TP73 tumor protein p73
TRAIP TRAF interacting protein
TRAPPC4 trafficking protein particle complex 4
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM22 tripartite motif containing 22
TRIM36 tripartite motif containing 36
TSC22D4 TSC22 domain family, member 4
TSHB thyroid stimulating hormone, beta
TSKU tsukushi, small leucine rich proteoglycan
TSPAN2 tetraspanin 2
TTLL10 tubulin tyrosine ligase-like family member 10
TUBA1B tubulin, alpha 1b
TUBB6 tubulin, beta 6 class V
TXNL4B thioredoxin-like 4B
TYMS thymidylate synthetase
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UBE2T ubiquitin-conjugating enzyme E2T
UGP2 UDP-glucose pyrophosphorylase 2
USP2 ubiquitin specific peptidase 2
USP48 ubiquitin specific peptidase 48
VSIG10 V-set and immunoglobulin domain containing 10
VSTM2L V-set and transmembrane domain containing 2 like
VWCE von Willebrand factor C and EGF domains
WFDC3 WAP four-disulfide core domain 3
WNT11 wingless-type MMTV integration site family, member 11
WNT9A wingless-type MMTV integration site family, member 9A
WWC2 WW and C2 domain containing 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZFHX3 zinc finger homeobox 3
ZGRF1 zinc finger, GRF-type containing 1
ZMYND10 zinc finger, MYND-type containing 10
ZNF107 zinc finger protein 107
ZNF695 zinc finger protein 695
ZNF732 zinc finger protein 732
ZNF786 zinc finger protein 786
ZNF90 zinc finger protein 90

low expression

Symbol Name
SRSF8 serine/arginine-rich splicing factor 8