Acute Myeloid Leukemia_LAML_TCGA-AB-2963-03A-01T-0734-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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Genes

339 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2963-03A-01T-0734-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABHD10 abhydrolase domain containing 10
ACRV1 acrosomal vesicle protein 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACTBL2 actin, beta-like 2
ACTL6A actin-like 6A
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AGA aspartylglucosaminidase
AGGF1 angiogenic factor with G patch and FHA domains 1
AGMAT agmatine ureohydrolase (agmatinase)
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ANKRD22 ankyrin repeat domain 22
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
API5 apoptosis inhibitor 5
ARHGAP11A Rho GTPase activating protein 11A
ARL13B ADP-ribosylation factor-like 13B
ARL8B ADP-ribosylation factor-like 8B
ARMC10 armadillo repeat containing 10
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
AZI2 5-azacytidine induced 2
AZIN1 antizyme inhibitor 1
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BBS10 Bardet-Biedl syndrome 10
BEX1 brain expressed, X-linked 1
BFAR bifunctional apoptosis regulator
BLM Bloom syndrome, RecQ helicase-like
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
C10ORF2 chromosome 10 open reading frame 2
C12ORF29 chromosome 12 open reading frame 29
C22ORF31 chromosome 22 open reading frame 31
C2ORF69 chromosome 2 open reading frame 69
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAT catalase
CBX3 chromobox homolog 3
CCDC121 coiled-coil domain containing 121
CCDC43 coiled-coil domain containing 43
CCDC58 coiled-coil domain containing 58
CCPG1 cell cycle progression 1
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CENPL centromere protein L
CENPQ centromere protein Q
CETN3 centrin, EF-hand protein, 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CREG1 cellular repressor of E1A-stimulated genes 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSNK1G3 casein kinase 1, gamma 3
CT45A1 cancer/testis antigen family 45, member A1
CT45A3 cancer/testis antigen family 45, member A3
CT45A4 cancer/testis antigen family 45, member A4
CT45A5 cancer/testis antigen family 45, member A5
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CUL2 cullin 2
CWC22 CWC22 spliceosome-associated protein
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DBIL5P diazepam binding inhibitor-like 5, pseudogene
DCTN5 dynactin 5 (p25)
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDIAS DNA damage-induced apoptosis suppressor
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEFA1B defensin, alpha 1B
DEK DEK proto-oncogene
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DMP1 dentin matrix acidic phosphoprotein 1
DPY19L1 dpy-19-like 1 (C. elegans)
DSCC1 DNA replication and sister chromatid cohesion 1
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
DYM dymeclin
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EAF2 ELL associated factor 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB1 EF-hand calcium binding domain 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF4E eukaryotic translation initiation factor 4E
EIF5B eukaryotic translation initiation factor 5B
ELP4 elongator acetyltransferase complex subunit 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPRS glutamyl-prolyl-tRNA synthetase
ERGIC2 ERGIC and golgi 2
ERLIN1 ER lipid raft associated 1
ERMP1 endoplasmic reticulum metallopeptidase 1
ERO1L ERO1-like (S. cerevisiae)
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
ETV5 ets variant 5
FAM136A family with sequence similarity 136, member A
FAM175B family with sequence similarity 175, member B
FAM72A family with sequence similarity 72, member A
FAM72B family with sequence similarity 72, member B
FAM72D family with sequence similarity 72, member D
FAM86C1 family with sequence similarity 86, member C1
FASTKD3 FAST kinase domains 3
FBXO45 F-box protein 45
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FGFBP3 fibroblast growth factor binding protein 3
FRG1B FSHD region gene 1 family, member B
FRMD3 FERM domain containing 3
FSD1L fibronectin type III and SPRY domain containing 1-like
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALP galanin-like peptide
GARS glycyl-tRNA synthetase
GDI2 GDP dissociation inhibitor 2
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN5 gem (nuclear organelle) associated protein 5
GEMIN6 gem (nuclear organelle) associated protein 6
GGCT gamma-glutamylcyclotransferase
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GPR151 G protein-coupled receptor 151
GRPEL2 GrpE-like 2, mitochondrial (E. coli)
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTSF1 gametocyte specific factor 1
H2AFY2 H2A histone family, member Y2
HACL1 2-hydroxyacyl-CoA lyase 1
HAT1 histone acetyltransferase 1
HDAC2 histone deacetylase 2
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HS6ST3 heparan sulfate 6-O-sulfotransferase 3
HSPA4 heat shock 70kDa protein 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HULC hepatocellular carcinoma up-regulated long non-coding RNA
IARS isoleucyl-tRNA synthetase
IER3IP1 immediate early response 3 interacting protein 1
IFT57 intraflagellar transport 57
IKBIP IKBKB interacting protein
INIP INTS3 and NABP interacting protein
IPO5 importin 5
IPO7 importin 7
IPO8 importin 8
KDELC2 KDEL (Lys-Asp-Glu-Leu) containing 2
KDSR 3-ketodihydrosphingosine reductase
KIAA0020 KIAA0020
KIAA1715 KIAA1715
KIF1A kinesin family member 1A
KNOP1 lysine-rich nucleolar protein 1
KPNB1 karyopherin (importin) beta 1
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LAMP2 lysosomal-associated membrane protein 2
LARP4 La ribonucleoprotein domain family, member 4
LARP7 La ribonucleoprotein domain family, member 7
LCLAT1 lysocardiolipin acyltransferase 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC649330
LYRM2 LYR motif containing 2
LYRM7 LYR motif containing 7
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGEB2 melanoma antigen family B2
MAK16 MAK16 homolog (S. cerevisiae)
MALL mal, T-cell differentiation protein-like
MARC1 mitochondrial amidoxime reducing component 1
MCFD2 multiple coagulation factor deficiency 2
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
METTL18 methyltransferase like 18
MFAP3 microfibrillar-associated protein 3
MFSD1 major facilitator superfamily domain containing 1
MGAM maltase-glucoamylase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MORC2-AS1 MORC2 antisense RNA 1
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MPV17L MPV17 mitochondrial membrane protein-like
MRPL3 mitochondrial ribosomal protein L3
MRPL35 mitochondrial ribosomal protein L35
MRPS27 mitochondrial ribosomal protein S27
MRPS35 mitochondrial ribosomal protein S35
MS4A8 membrane-spanning 4-domains, subfamily A, member 8
MTAP methylthioadenosine phosphorylase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYCBP MYC binding protein
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MZT1 mitotic spindle organizing protein 1
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAP1L1 nucleosome assembly protein 1-like 1
NARS asparaginyl-tRNA synthetase
NCL nucleolin
NDC1 NDC1 transmembrane nucleoporin
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NIFK nucleolar protein interacting with the FHA domain of MKI67
NIP7 NIP7, nucleolar pre-rRNA processing protein
NKRF NFKB repressing factor
NLN neurolysin (metallopeptidase M3 family)
NMD3 NMD3 ribosome export adaptor
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NT5DC1 5'-nucleotidase domain containing 1
OCLN occludin
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OLA1 Obg-like ATPase 1
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OTOR otoraplin
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PARD6B par-6 family cell polarity regulator beta
PDCD2 programmed cell death 2
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PEG3 paternally expressed 3
PER3 period circadian clock 3
PGM1 phosphoglucomutase 1
PGRMC2 progesterone receptor membrane component 2
PHAX phosphorylated adaptor for RNA export
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PLA2G3 phospholipase A2, group III
PLAA phospholipase A2-activating protein
POGK pogo transposable element with KRAB domain
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PPA1 pyrophosphatase (inorganic) 1
PPAT phosphoribosyl pyrophosphate amidotransferase
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRSS41 protease, serine, 41
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
RAB27A RAB27A, member RAS oncogene family
RALBP1 ralA binding protein 1
RBM12 RNA binding motif protein 12
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RCC1 regulator of chromosome condensation 1
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RFK riboflavin kinase
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RHEBL1 Ras homolog enriched in brain like 1
RMI1 RecQ mediated genome instability 1
RNF6 ring finger protein (C3H2C3 type) 6
RPE ribulose-5-phosphate-3-epimerase
RPF2 ribosome production factor 2 homolog (S. cerevisiae)
RPL7 ribosomal protein L7
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
RSL24D1 ribosomal L24 domain containing 1
RWDD4 RWD domain containing 4
SAAL1 serum amyloid A-like 1
SCAMP1 secretory carrier membrane protein 1
SCARNA4 small Cajal body-specific RNA 4
SDAD1 SDA1 domain containing 1
SERBP1 SERPINE1 mRNA binding protein 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SET SET nuclear proto-oncogene
SGOL1 shugoshin-like 1 (S. pombe)
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SKAP2 src kinase associated phosphoprotein 2
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNORA21 small nucleolar RNA, H/ACA box 21
SNORA71D small nucleolar RNA, H/ACA box 71D
SNX14 sorting nexin 14
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPAG6 sperm associated antigen 6
SPAST spastin
SRGN serglycin
SRPK1 SRSF protein kinase 1
SRPRB signal recognition particle receptor, B subunit
SSB Sjogren syndrome antigen B (autoantigen La)
SV2B synaptic vesicle glycoprotein 2B
SYPL1 synaptophysin-like 1
TAAR5 trace amine associated receptor 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARS threonyl-tRNA synthetase
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TFDP3 transcription factor Dp family, member 3
TGDS TDP-glucose 4,6-dehydratase
THAP10 THAP domain containing 10
TIPRL TOR signaling pathway regulator
TLCD1 TLC domain containing 1
TM9SF3 transmembrane 9 superfamily member 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM192 transmembrane protein 192
TMEM209 transmembrane protein 209
TMEM38B transmembrane protein 38B
TMEM5 transmembrane protein 5
TMEM59 transmembrane protein 59
TMEM87B transmembrane protein 87B
TMEM97 transmembrane protein 97
TMX1 thioredoxin-related transmembrane protein 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TOR1AIP1 torsin A interacting protein 1
TP53TG5 TP53 target 5
TRIQK triple QxxK/R motif containing
TRMT5 tRNA methyltransferase 5
TSSK1B testis-specific serine kinase 1B
TTC30A tetratricopeptide repeat domain 30A
TTC30B tetratricopeptide repeat domain 30B
TUBE1 tubulin, epsilon 1
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
TXNRD1 thioredoxin reductase 1
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ULBP1 UL16 binding protein 1
UMPS uridine monophosphate synthetase
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VAMP7 vesicle-associated membrane protein 7
VBP1 von Hippel-Lindau binding protein 1
VRK1 vaccinia related kinase 1
VTA1 vesicle (multivesicular body) trafficking 1
WDR3 WD repeat domain 3
WDR36 WD repeat domain 36
WDR43 WD repeat domain 43
WDR89 WD repeat domain 89
WISP1 WNT1 inducible signaling pathway protein 1
XPO1 exportin 1
XPO5 exportin 5
XPOT exportin, tRNA
YEATS4 YEATS domain containing 4
YIPF5 Yip1 domain family, member 5
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB6 zinc finger and BTB domain containing 6
ZC3H15 zinc finger CCCH-type containing 15
ZDHHC13 zinc finger, DHHC-type containing 13
ZFP2 ZFP2 zinc finger protein
ZMPSTE24 zinc metallopeptidase STE24
ZNF214 zinc finger protein 214
ZNF215 zinc finger protein 215
ZNF442 zinc finger protein 442
ZNF492 zinc finger protein 492
ZNF705D zinc finger protein 705D
ZNHIT6 zinc finger, HIT-type containing 6
ZPBP zona pellucida binding protein

low expression

Symbol Name
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2