Acute Myeloid Leukemia_LAML_TCGA-AB-2921-03A-01T-0740-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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Genes

192 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2921-03A-01T-0740-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ACYP2 acylphosphatase 2, muscle type
AEN apoptosis enhancing nuclease
ANXA7 annexin A7
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APTX aprataxin
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASIC5 acid sensing (proton gated) ion channel family member 5
BCAP31 B-cell receptor-associated protein 31
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BSPRY B-box and SPRY domain containing
BST2 bone marrow stromal cell antigen 2
C11ORF85 chromosome 11 open reading frame 85
C15ORF56 chromosome 15 open reading frame 56
C17ORF89 chromosome 17 open reading frame 89
C2ORF80 chromosome 2 open reading frame 80
C5ORF60 chromosome 5 open reading frame 60
C7ORF25 chromosome 7 open reading frame 25
C7ORF57 chromosome 7 open reading frame 57
C9ORF139 chromosome 9 open reading frame 139
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CAPN14 calpain 14
CAT catalase
CBWD2 COBW domain containing 2
CBWD6 COBW domain containing 6
CCNA1 cyclin A1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CFAP53 cilia and flagella associated protein 53
CLYBL citrate lyase beta like
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYB5A cytochrome b5 type A (microsomal)
DEC1 deleted in esophageal cancer 1
DGKA diacylglycerol kinase, alpha 80kDa
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNLZ DNL-type zinc finger
DSCR9 Down syndrome critical region 9 (non-protein coding)
EMB embigin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EXOC3-AS1 EXOC3 antisense RNA 1
FAM219B family with sequence similarity 219, member B
FAM47E family with sequence similarity 47, member E
FAM92A1 family with sequence similarity 92, member A1
FBXL8 F-box and leucine-rich repeat protein 8
FBXO10 F-box protein 10
FBXO22-AS1 FBXO22 antisense RNA 1
FBXO44 F-box protein 44
FDXR ferredoxin reductase
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GEMIN7 gem (nuclear organelle) associated protein 7
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GK2 glycerol kinase 2
GOLGA8A golgin A8 family, member A
GOLGA8EP golgin A8 family, member E, pseudogene
GOLGA8IP golgin A8 family, member I, pseudogene
GPR89B G protein-coupled receptor 89B
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HOXC4 homeobox C4
HSF4 heat shock transcription factor 4
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDNK idnK, gluconokinase homolog (E. coli)
IL2RA interleukin 2 receptor, alpha
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
JPH1 junctophilin 1
KAT2A K(lysine) acetyltransferase 2A
KCTD8 potassium channel tetramerization domain containing 8
KRT14 keratin 14, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LDHC lactate dehydrogenase C
LIG4 ligase IV, DNA, ATP-dependent
LIPC lipase, hepatic
LOC100240735 uncharacterized LOC100240735
LOC100270804 uncharacterized LOC100270804
LOC391322 D-dopachrome tautomerase-like
LOC643923 uncharacterized LOC643923
LOC727924 uncharacterized LOC727924
LRRC69 leucine rich repeat containing 69
LVRN laeverin
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP10 microtubule-associated protein 10
MDH1B malate dehydrogenase 1B, NAD (soluble)
MEGF11 multiple EGF-like-domains 11
METTL23 methyltransferase like 23
MIR155HG MIR155 host gene
MORC2-AS1 MORC2 antisense RNA 1
MPI mannose phosphate isomerase
MRPL36 mitochondrial ribosomal protein L36
MRPL57 mitochondrial ribosomal protein L57
MRPS23 mitochondrial ribosomal protein S23
MTO1 mitochondrial tRNA translation optimization 1
NECAP2 NECAP endocytosis associated 2
NFS1 NFS1 cysteine desulfurase
NLRP2 NLR family, pyrin domain containing 2
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OCA2 oculocutaneous albinism II
OCSTAMP osteoclast stimulatory transmembrane protein
ODF1 outer dense fiber of sperm tails 1
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OR1Q1 olfactory receptor, family 1, subfamily Q, member 1
OSCP1 organic solute carrier partner 1
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PABPC1L poly(A) binding protein, cytoplasmic 1-like
PDCD2L programmed cell death 2-like
PDLIM1 PDZ and LIM domain 1
PILRB paired immunoglobin-like type 2 receptor beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKD1L3 polycystic kidney disease 1-like 3
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PRORSD1P prolyl-tRNA synthetase associated domain containing 1, pseudogene
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PRR23B proline rich 23B
PSMG4 proteasome (prosome, macropain) assembly chaperone 4
PTPMT1 protein tyrosine phosphatase, mitochondrial 1
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
QDPR quinoid dihydropteridine reductase
RABEPK Rab9 effector protein with kelch motifs
RBKS ribokinase
RBM45 RNA binding motif protein 45
RCC1 regulator of chromosome condensation 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPL23AP82 ribosomal protein L23a pseudogene 82
SARDH sarcosine dehydrogenase
SCARNA23 small Cajal body-specific RNA 23
SCN2A sodium channel, voltage gated, type II alpha subunit
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SLC17A1 solute carrier family 17 (organic anion transporter), member 1
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9C2 solute carrier family 9, member C2 (putative)
SMCO2 single-pass membrane protein with coiled-coil domains 2
SMIM3 small integral membrane protein 3
SNHG10 small nucleolar RNA host gene 10
SNHG4 small nucleolar RNA host gene 4
SNORA11E small nucleolar RNA, H/ACA box 11E
SPAG8 sperm associated antigen 8
SPESP1 sperm equatorial segment protein 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPNS3 spinster homolog 3 (Drosophila)
STON1 stonin 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
STX16 syntaxin 16
TCTA T-cell leukemia translocation altered
TIGD1 tigger transposable element derived 1
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TMEM186 transmembrane protein 186
TMEM217 transmembrane protein 217
TMEM42 transmembrane protein 42
TMOD4 tropomodulin 4 (muscle)
TNNC1 troponin C type 1 (slow)
TOMM34 translocase of outer mitochondrial membrane 34
TREML4 triggering receptor expressed on myeloid cells-like 4
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TSPAN31 tetraspanin 31
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
TTLL9 tubulin tyrosine ligase-like family member 9
UNC13A unc-13 homolog A (C. elegans)
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
WDR35 WD repeat domain 35
WDR66 WD repeat domain 66
WDR77 WD repeat domain 77
WHAMMP2 WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 2
XBP1 X-box binding protein 1
XPC xeroderma pigmentosum, complementation group C
ZCCHC17 zinc finger, CCHC domain containing 17
ZDHHC19 zinc finger, DHHC-type containing 19
ZMYND12 zinc finger, MYND-type containing 12
ZNF330 zinc finger protein 330
ZSCAN32 zinc finger and SCAN domain containing 32

low expression

Symbol Name
CDYL chromodomain protein, Y-like
CEP192 centrosomal protein 192kDa
CREBBP CREB binding protein
EP300 E1A binding protein p300
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
OTULIN OTU deubiquitinase with linear linkage specificity
PPP4R1 protein phosphatase 4, regulatory subunit 1
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
SPEN spen family transcriptional repressor
STK24 serine/threonine kinase 24
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)