Acute Myeloid Leukemia_LAML_TCGA-AB-2909-03A-01T-0744-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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Genes

424 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2909-03A-01T-0744-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADAT aminoadipate aminotransferase
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD12B abhydrolase domain containing 12B
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADCY3 adenylate cyclase 3
AFAP1L1 actin filament associated protein 1-like 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1
ANGPT1 angiopoietin 1
ANKRD13B ankyrin repeat domain 13B
ANPEP alanyl (membrane) aminopeptidase
AOX2P aldehyde oxidase 2 pseudogene
APLN apelin
APOA5 apolipoprotein A-V
AR androgen receptor
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARL10 ADP-ribosylation factor-like 10
ARL9 ADP-ribosylation factor-like 9
ASPA aspartoacylase
ATF3 activating transcription factor 3
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BAALC brain and acute leukemia, cytoplasmic
BAALC-AS2 BAALC antisense RNA 2
BAGE2 B melanoma antigen family, member 2
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMP6 bone morphogenetic protein 6
BTN1A1 butyrophilin, subfamily 1, member A1
BZW2 basic leucine zipper and W2 domains 2
C10ORF107 chromosome 10 open reading frame 107
C15ORF56 chromosome 15 open reading frame 56
C1ORF112 chromosome 1 open reading frame 112
C1ORF186 chromosome 1 open reading frame 186
C2CD2 C2 calcium-dependent domain containing 2
C2CD4B C2 calcium-dependent domain containing 4B
C7ORF57 chromosome 7 open reading frame 57
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCOCO2 calcium binding and coiled-coil domain 2
CARD10 caspase recruitment domain family, member 10
CASKIN2 CASK interacting protein 2
CBR3 carbonyl reductase 3
CCDC144B coiled-coil domain containing 144B (pseudogene)
CCND1 cyclin D1
CCND2 cyclin D2
CCNL1 cyclin L1
CCNT2 cyclin T2
CD3D CD3d molecule, delta (CD3-TCR complex)
CD69 CD69 molecule
CDKL3 cyclin-dependent kinase-like 3
CDR2L cerebellar degeneration-related protein 2-like
CEP170P1 centrosomal protein 170kDa pseudogene 1
CEP68 centrosomal protein 68kDa
CETP cholesteryl ester transfer protein, plasma
CHD4 chromodomain helicase DNA binding protein 4
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
CLIP3 CAP-GLY domain containing linker protein 3
CLK1 CDC-like kinase 1
CMIP c-Maf inducing protein
COMP cartilage oligomeric matrix protein
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CPNE7 copine VII
CRAMP1L Crm, cramped-like (Drosophila)
CRHBP corticotropin releasing hormone binding protein
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRYL1 crystallin, lambda 1
CSRNP1 cysteine-serine-rich nuclear protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
DCHS1 dachsous cadherin-related 1
DCST1 DC-STAMP domain containing 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DENND5A DENN/MADD domain containing 5A
DEXI Dexi homolog (mouse)
DFNB31 deafness, autosomal recessive 31
DGKH diacylglycerol kinase, eta
DIAPH1 diaphanous-related formin 1
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DLG3 discs, large homolog 3 (Drosophila)
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DMD dystrophin
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPYSL2 dihydropyrimidinase-like 2
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EFNB1 ephrin-B1
EFR3B EFR3 homolog B (S. cerevisiae)
ELMO1 engulfment and cell motility 1
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EPN2 epsin 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ESYT2 extended synaptotagmin-like protein 2
ETV6 ets variant 6
EVPL envoplakin
FAM106A family with sequence similarity 106, member A
FAM159A family with sequence similarity 159, member A
FAM171A1 family with sequence similarity 171, member A1
FAM53A family with sequence similarity 53, member A
FAM57A family with sequence similarity 57, member A
FBXO38 F-box protein 38
FEM1C fem-1 homolog c (C. elegans)
FGD5 FYVE, RhoGEF and PH domain containing 5
FGF22 fibroblast growth factor 22
FLJ13224 uncharacterized LOC79857
FLT4 fms-related tyrosine kinase 4
FOSL1 FOS-like antigen 1
FOXN3 forkhead box N3
FRMPD2B FERM and PDZ domain containing 2B, pseudogene
FSCN1 fascin actin-bundling protein 1
GATSL2 GATS protein-like 2
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GGACT gamma-glutamylamine cyclotransferase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPC1 glypican 1
GPR150 G protein-coupled receptor 150
GRAMD1A GRAM domain containing 1A
GRIK5 glutamate receptor, ionotropic, kainate 5
H2AFY H2A histone family, member Y
HEATR5B HEAT repeat containing 5B
HERPUD2 HERPUD family member 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AB histone cluster 1, H2ab
HIST1H2AD histone cluster 1, H2ad
HIST1H2AE histone cluster 1, H2ae
HIST1H2AG histone cluster 1, H2ag
HIST1H2AH histone cluster 1, H2ah
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HIST1H2AL histone cluster 1, H2al
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BL histone cluster 1, H2bl
HIST1H3A histone cluster 1, H3a
HIST1H3C histone cluster 1, H3c
HIST1H3F histone cluster 1, H3f
HIST1H4A histone cluster 1, H4a
HIST1H4E histone cluster 1, H4e
HIST1H4F histone cluster 1, H4f
HIST1H4K histone cluster 1, H4k
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST2H2BE histone cluster 2, H2be
HIST2H2BF histone cluster 2, H2bf
HIST2H3D histone cluster 2, H3d
HOMER2 homer scaffolding protein 2
HPGDS hematopoietic prostaglandin D synthase
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HSPG2 heparan sulfate proteoglycan 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDI2-AS1 IDI2 antisense RNA 1
IFRD1 interferon-related developmental regulator 1
IL17D interleukin 17D
INF2 inverted formin, FH2 and WH2 domain containing
INO80 INO80 complex subunit
INVS inversin
IQGAP2 IQ motif containing GTPase activating protein 2
IRGM immunity-related GTPase family, M
IRGQ immunity-related GTPase family, Q
IRX1 iroquois homeobox 1
ISPD isoprenoid synthase domain containing
ISYNA1 inositol-3-phosphate synthase 1
ITGA9 integrin, alpha 9
ITPKA inositol-trisphosphate 3-kinase A
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUN jun proto-oncogene
KANK3 KN motif and ankyrin repeat domains 3
KANK4 KN motif and ankyrin repeat domains 4
KCNK6 potassium channel, two pore domain subfamily K, member 6
KIAA1324L KIAA1324-like
KIAA1522 KIAA1522
KIAA1549 KIAA1549
KIF26A kinesin family member 26A
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
KLHL15 kelch-like family member 15
KRBA1 KRAB-A domain containing 1
KRTAP10-2 keratin associated protein 10-2
LEKR1 leucine, glutamate and lysine rich 1
LIMS1 LIM and senescent cell antigen-like domains 1
LIPI lipase, member I
LOC284379 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene
LOC285074 anaphase promoting complex subunit 1 pseudogene
LOC340357 uncharacterized LOC340357
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOC728743 zinc finger protein pseudogene
LOC728989 phosphodiesterase 4D interacting protein pseudogene
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1
LPIN1 lipin 1
LRP6 low density lipoprotein receptor-related protein 6
LRRC28 leucine rich repeat containing 28
LRRK1 leucine-rich repeat kinase 1
LRWD1 leucine-rich repeats and WD repeat domain containing 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTK leukocyte receptor tyrosine kinase
LUZP1 leucine zipper protein 1
MACF1 microtubule-actin crosslinking factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4 microtubule-associated protein 4
MARCKSL1 MARCKS-like 1
MAST1 microtubule associated serine/threonine kinase 1
MAST4 microtubule associated serine/threonine kinase family member 4
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MDK midkine (neurite growth-promoting factor 2)
MDN1 MDN1, midasin homolog (yeast)
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MEST mesoderm specific transcript
METRN meteorin, glial cell differentiation regulator
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MFSD6 major facilitator superfamily domain containing 6
MLXIP MLX interacting protein
MOB3B MOB kinase activator 3B
MOV10 Mov10 RISC complex RNA helicase
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
NCOA7 nuclear receptor coactivator 7
NDRG2 NDRG family member 2
NEUROG2 neurogenin 2
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NIN ninein (GSK3B interacting protein)
NLGN2 neuroligin 2
NPPC natriuretic peptide C
NPR3 natriuretic peptide receptor 3
NTSR1 neurotensin receptor 1 (high affinity)
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
OCM2 oncomodulin 2
OR1C1 olfactory receptor, family 1, subfamily C, member 1
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR4N2 olfactory receptor, family 4, subfamily N, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
OTUD1 OTU deubiquitinase 1
OVCH1 ovochymase 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PAOX polyamine oxidase (exo-N4-amino)
PAX4 paired box 4
PBX4 pre-B-cell leukemia homeobox 4
PDGFC platelet derived growth factor C
PER3 period circadian clock 3
PERM1 PPARGC1 and ESRR induced regulator, muscle 1
PIAS2 protein inhibitor of activated STAT, 2
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLK3 polo-like kinase 3
PLXND1 plexin D1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNMA1 paraneoplastic Ma antigen 1
POMC proopiomelanocortin
POTEF POTE ankyrin domain family, member F
POU6F1 POU class 6 homeobox 1
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRAP1 proline-rich acidic protein 1
PRCD progressive rod-cone degeneration
PRKCZ protein kinase C, zeta
PRPF8 pre-mRNA processing factor 8
PRX periaxin
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTTG1IP pituitary tumor-transforming 1 interacting protein
PURB purine-rich element binding protein B
PXDC1 PX domain containing 1
PYGL phosphorylase, glycogen, liver
PYHIN1 pyrin and HIN domain family, member 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAET1E retinoic acid early transcript 1E
RAET1G retinoic acid early transcript 1G
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RASA4CP RAS p21 protein activator 4C, pseudogene
RASL10A RAS-like, family 10, member A
RBPMS RNA binding protein with multiple splicing
RCSD1 RCSD domain containing 1
RD3 retinal degeneration 3
REPS1 RALBP1 associated Eps domain containing 1
RIMKLB ribosomal modification protein rimK-like family member B
RIPPLY3 ripply transcriptional repressor 3
RNASE9 ribonuclease, RNase A family, 9 (non-active)
RNF220 ring finger protein 220
RPS6KL1 ribosomal protein S6 kinase-like 1
SATB1 SATB homeobox 1
SBDS Shwachman-Bodian-Diamond syndrome
SCARNA11 small Cajal body-specific RNA 11
SCARNA21 small Cajal body-specific RNA 21
SCARNA8 small Cajal body-specific RNA 8
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SEPT11 septin 11
SEPT5 septin 5
SERINC4 serine incorporator 4
SFPQ splicing factor proline/glutamine-rich
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHH sonic hedgehog
SIDT1 SID1 transmembrane family, member 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMAGP small cell adhesion glycoprotein
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMO smoothened, frizzled class receptor
SMOX spermine oxidase
SMYD3 SET and MYND domain containing 3
SNHG15 small nucleolar RNA host gene 15
SNORA29 small nucleolar RNA, H/ACA box 29
SNORA2A small nucleolar RNA, H/ACA box 2A
SNORA2B small nucleolar RNA, H/ACA box 2B
SNORA66 small nucleolar RNA, H/ACA box 66
SNORA74A small nucleolar RNA, H/ACA box 74A
SNORA76A small nucleolar RNA, H/ACA box 76A
SNORA9 small nucleolar RNA, H/ACA box 9
SNURF SNRPN upstream reading frame
SOX15 SRY (sex determining region Y)-box 15
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SSBP2 single-stranded DNA binding protein 2
SSFA2 sperm specific antigen 2
SSX6 synovial sarcoma, X breakpoint 6 (pseudogene)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAP2 signal transducing adaptor family member 2
STAT5B signal transducer and activator of transcription 5B
STRBP spermatid perinuclear RNA binding protein
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TBC1D16 TBC1 domain family, member 16
TBC1D3P1-DHX40P1 TBC1D3P1-DHX40P1 readthrough transcribed pseudogene
TCP11L1 t-complex 11, testis-specific-like 1
TCTEX1D1 Tctex1 domain containing 1
TEC tec protein tyrosine kinase
TENM1 teneurin transmembrane protein 1
TERC telomerase RNA component
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THAP8 THAP domain containing 8
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM241 transmembrane protein 241
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOX thymocyte selection-associated high mobility group box
TRA2B transformer 2 beta homolog (Drosophila)
TRAF3IP2 TRAF3 interacting protein 2
TRAF4 TNF receptor-associated factor 4
TRAF5 TNF receptor-associated factor 5
TRAT1 T cell receptor associated transmembrane adaptor 1
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRIO trio Rho guanine nucleotide exchange factor
TSPAN7 tetraspanin 7
TTLL6 tubulin tyrosine ligase-like family member 6
TXLNB taxilin beta
UBR4 ubiquitin protein ligase E3 component n-recognin 4
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
UST uronyl-2-sulfotransferase
UTS2 urotensin 2
VAV3 vav 3 guanine nucleotide exchange factor
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
YEATS2 YEATS domain containing 2
YLPM1 YLP motif containing 1
YPEL5 yippee-like 5 (Drosophila)
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBTB8A zinc finger and BTB domain containing 8A
ZCCHC7 zinc finger, CCHC domain containing 7
ZFHX3 zinc finger homeobox 3
ZMAT3 zinc finger, matrin-type 3
ZNF300 zinc finger protein 300
ZNF321P zinc finger protein 321, pseudogene
ZNF440 zinc finger protein 440
ZNF609 zinc finger protein 609
ZSCAN23 zinc finger and SCAN domain containing 23
ZXDA zinc finger, X-linked, duplicated A
ZXDB zinc finger, X-linked, duplicated B

low expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CARKD carbohydrate kinase domain containing
CLP1 cleavage and polyadenylation factor I subunit 1
FANCC Fanconi anemia, complementation group C
FBXO28 F-box protein 28
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
METTL14 methyltransferase like 14
MFF mitochondrial fission factor
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4
PPP4R2 protein phosphatase 4, regulatory subunit 2
RAP1GAP2 RAP1 GTPase activating protein 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEC24D SEC24 family member D
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SMG8 SMG8 nonsense mediated mRNA decay factor
SNX19 sorting nexin 19
TM2D2 TM2 domain containing 2
TMCO1 transmembrane and coiled-coil domains 1
TMEM165 transmembrane protein 165
TMEM199 transmembrane protein 199
TMEM203 transmembrane protein 203
UBA3 ubiquitin-like modifier activating enzyme 3
UBE2E3 ubiquitin-conjugating enzyme E2E 3