Acute Myeloid Leukemia_LAML_TCGA-AB-2828-03A-01T-0734-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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Genes

277 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2828-03A-01T-0734-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACPP acid phosphatase, prostate
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADGRG7 adhesion G protein-coupled receptor G7
AFAP1 actin filament associated protein 1
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AKAP7 A kinase (PRKA) anchor protein 7
ALOX15 arachidonate 15-lipoxygenase
ANKRD34C ankyrin repeat domain 34C
ANKRD36BP1 ankyrin repeat domain 36B pseudogene 1
ANO6 anoctamin 6
ANP32A-IT1 ANP32A intronic transcript 1
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA5 annexin A5
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APAF1 apoptotic peptidase activating factor 1
ARFIP1 ADP-ribosylation factor interacting protein 1
ARL11 ADP-ribosylation factor-like 11
ARL5A ADP-ribosylation factor-like 5A
ARMT1 acidic residue methyltransferase 1
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATOH1 atonal homolog 1 (Drosophila)
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BCL10 B-cell CLL/lymphoma 10
C12ORF4 chromosome 12 open reading frame 4
C2ORF78 chromosome 2 open reading frame 78
C7ORF33 chromosome 7 open reading frame 33
CACUL1 CDK2-associated, cullin domain 1
CCNY cyclin Y
CCNYL1 cyclin Y-like 1
CCR2 chemokine (C-C motif) receptor 2
CCSAP centriole, cilia and spindle-associated protein
CD209 CD209 molecule
CD302 CD302 molecule
CD86 CD86 molecule
CD93 CD93 molecule
CEP55 centrosomal protein 55kDa
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC12B C-type lectin domain family 12, member B
CLEC1A C-type lectin domain family 1, member A
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
COLCA2 colorectal cancer associated 2
COLEC12 collectin sub-family member 12
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CRLF3 cytokine receptor-like factor 3
CSF1R colony stimulating factor 1 receptor
CST9 cystatin 9 (testatin)
CTSS cathepsin S
CYB5R4 cytochrome b5 reductase 4
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCP2 decapping mRNA 2
DDIAS DNA damage-induced apoptosis suppressor
DFNA5 deafness, autosomal dominant 5
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIRC2 disrupted in renal carcinoma 2
DKK4 dickkopf WNT signaling pathway inhibitor 4
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DTX4 deltex 4, E3 ubiquitin ligase
DUSP6 dual specificity phosphatase 6
ELOVL5 ELOVL fatty acid elongase 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENHO energy homeostasis associated
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EVI5 ecotropic viral integration site 5
EXD1 exonuclease 3'-5' domain containing 1
EXT1 exostosin glycosyltransferase 1
F13A1 coagulation factor XIII, A1 polypeptide
F5 coagulation factor V (proaccelerin, labile factor)
FAM102B family with sequence similarity 102, member B
FAM105A family with sequence similarity 105, member A
FAM117B family with sequence similarity 117, member B
FAM120A family with sequence similarity 120A
FAM49B family with sequence similarity 49, member B
FAM72A family with sequence similarity 72, member A
FAM72B family with sequence similarity 72, member B
FBP1 fructose-1,6-bisphosphatase 1
FBXL5 F-box and leucine-rich repeat protein 5
FGL2 fibrinogen-like 2
FXYD4 FXYD domain containing ion transport regulator 4
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GALP galanin-like peptide
GANC glucosidase, alpha; neutral C
GHRH growth hormone releasing hormone
GIF gastric intrinsic factor (vitamin B synthesis)
GIMAP4 GTPase, IMAP family member 4
GIMAP8 GTPase, IMAP family member 8
GMCL1P1 germ cell-less, spermatogenesis associated 1 pseudogene 1
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GOLGA6L6 golgin A6 family-like 6
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPR26 G protein-coupled receptor 26
GRM8 glutamate receptor, metabotropic 8
HEATR5A HEAT repeat containing 5A
HIATL1 hippocampus abundant transcript-like 1
HK2 hexokinase 2
HOOK3 hook microtubule-tethering protein 3
HOXD10 homeobox D10
HOXD3 homeobox D3
HOXD8 homeobox D8
HPS5 Hermansky-Pudlak syndrome 5
HPSE heparanase
IGSF6 immunoglobulin superfamily, member 6
IL10RA interleukin 10 receptor, alpha
IL13RA1 interleukin 13 receptor, alpha 1
IL2 interleukin 2
INIP INTS3 and NABP interacting protein
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRS1 insulin receptor substrate 1
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNIP4-IT1 KCNIP4 intronic transcript 1
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCTD12 potassium channel tetramerization domain containing 12
KIF5B kinesin family member 5B
KLHL8 kelch-like family member 8
LAMB3 laminin, beta 3
LBR lamin B receptor
LENEP lens epithelial protein
LINC00244 long intergenic non-protein coding RNA 244
LINC00324 long intergenic non-protein coding RNA 324
LINC00479 long intergenic non-protein coding RNA 479
LIPN lipase, family member N
LMNB1 lamin B1
LOC100129034 uncharacterized LOC100129034
LOC100129550 uncharacterized LOC100129550
LOC644936 actin, beta pseudogene
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LYZ lysozyme
MB21D1 Mab-21 domain containing 1
MCMBP minichromosome maintenance complex binding protein
MDFIC MyoD family inhibitor domain containing
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MEFV Mediterranean fever
MEGF10 multiple EGF-like-domains 10
MEIS3P1 Meis homeobox 3 pseudogene 1
MGC12916 uncharacterized protein MGC12916
MOG myelin oligodendrocyte glycoprotein
MPEG1 macrophage expressed 1
MRVI1 murine retrovirus integration site 1 homolog
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTM1 myotubularin 1
MTMR11 myotubularin related protein 11
MTMR6 myotubularin related protein 6
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYH11 myosin, heavy chain 11, smooth muscle
NAGA N-acetylgalactosaminidase, alpha-
NAIP NLR family, apoptosis inhibitory protein
NARS asparaginyl-tRNA synthetase
NEK6 NIMA-related kinase 6
NEK7 NIMA-related kinase 7
NLRC4 NLR family, CARD domain containing 4
NLRP3 NLR family, pyrin domain containing 3
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NRP1 neuropilin 1
NSF N-ethylmaleimide-sensitive factor
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
OGFRL1 opioid growth factor receptor-like 1
OR1F1 olfactory receptor, family 1, subfamily F, member 1
OR5B3 olfactory receptor, family 5, subfamily B, member 3
OR7E37P olfactory receptor, family 7, subfamily E, member 37 pseudogene
OSBPL11 oxysterol binding protein-like 11
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PDZD9 PDZ domain containing 9
PGM2 phosphoglucomutase 2
PHACTR2 phosphatase and actin regulator 2
PIK3CD-AS1 PIK3CD antisense RNA 1
PLA2G5 phospholipase A2, group V
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
POTEA POTE ankyrin domain family, member A
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PWWP2A PWWP domain containing 2A
QKI QKI, KH domain containing, RNA binding
QPCT glutaminyl-peptide cyclotransferase
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB22A RAB22A, member RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
REEP5 receptor accessory protein 5
RFK riboflavin kinase
RHOU ras homolog family member U
RP2 retinitis pigmentosa 2 (X-linked recessive)
RRN3P2 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
SAMHD1 SAM domain and HD domain 1
SCLT1 sodium channel and clathrin linker 1
SEC24A SEC24 family member A
SEPT2 septin 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2B3 SH2B adaptor protein 3
SLC16A6 solute carrier family 16, member 6
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC25A40 solute carrier family 25, member 40
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SMIM14 small integral membrane protein 14
SMIM15 small integral membrane protein 15
SNX18 sorting nexin 18
SNX27 sorting nexin family member 27
SNX30 sorting nexin family member 30
SOAT1 sterol O-acyltransferase 1
SPATS1 spermatogenesis associated, serine-rich 1
SPOPL speckle-type POZ protein-like
SPRED1 sprouty-related, EVH1 domain containing 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STARD7 StAR-related lipid transfer (START) domain containing 7
STK38L serine/threonine kinase 38 like
STX12 syntaxin 12
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SULF2 sulfatase 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYK spleen tyrosine kinase
SYNGR4 synaptogyrin 4
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TEX12 testis expressed 12
TGFBI transforming growth factor, beta-induced, 68kDa
TICAM2 toll-like receptor adaptor molecule 2
TLDC2 TBC/LysM-associated domain containing 2
TLR5 toll-like receptor 5
TMCC3 transmembrane and coiled-coil domain family 3
TMED2 transmembrane emp24 domain trafficking protein 2
TMED5 transmembrane emp24 protein transport domain containing 5
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM132A transmembrane protein 132A
TMEM167A transmembrane protein 167A
TMEM170B transmembrane protein 170B
TMEM252 transmembrane protein 252
TMEM33 transmembrane protein 33
TMPO thymopoietin
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNNC1 troponin C type 1 (slow)
TULP4 tubby like protein 4
UEVLD UEV and lactate/malate dehyrogenase domains
UHRF1BP1L UHRF1 binding protein 1-like
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
ZFHX3 zinc finger homeobox 3
ZFP57 ZFP57 zinc finger protein
ZNF106 zinc finger protein 106
ZNF217 zinc finger protein 217
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZSWIM6 zinc finger, SWIM-type containing 6

low expression

Symbol Name
ANO10 anoctamin 10
ARMCX6 armadillo repeat containing, X-linked 6
ASB8 ankyrin repeat and SOCS box containing 8
BOLA1 bolA family member 1
C1ORF50 chromosome 1 open reading frame 50
CERS5 ceramide synthase 5
COX14 COX14 cytochrome c oxidase assembly factor
CRY1 cryptochrome circadian clock 1
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
GOLGA2 golgin A2
KANSL2 KAT8 regulatory NSL complex subunit 2
KLC4 kinesin light chain 4
LOC100132215 uncharacterized LOC100132215
MCRS1 microspherule protein 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NAP1L4 nucleosome assembly protein 1-like 4
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PGAP2 post-GPI attachment to proteins 2
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SUGP1 SURP and G patch domain containing 1