Acute Myeloid Leukemia_LAML_TCGA-AB-2826-03A-01T-0734-13 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Acute Myeloid Leukemia_LAML (The Cancer Genome Atlas)
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Genes

419 genes with high or low expression in Acute Myeloid Leukemia_LAML_TCGA-AB-2826-03A-01T-0734-13 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACAA2 acetyl-CoA acyltransferase 2
ACER3 alkaline ceramidase 3
ACOX2 acyl-CoA oxidase 2, branched chain
ACPP acid phosphatase, prostate
ACRV1 acrosomal vesicle protein 1
ACVR1B activin A receptor, type IB
ACYP2 acylphosphatase 2, muscle type
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRD1 adhesion G protein-coupled receptor D1
ADGRE1 adhesion G protein-coupled receptor E1
ADGRE3 adhesion G protein-coupled receptor E3
ADGRG2 adhesion G protein-coupled receptor G2
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
AIF1 allograft inflammatory factor 1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANKDD1A ankyrin repeat and death domain containing 1A
ANKRD22 ankyrin repeat domain 22
ANKRD34B ankyrin repeat domain 34B
ANKRD7 ankyrin repeat domain 7
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ANXA1 annexin A1
ANXA2P3 annexin A2 pseudogene 3
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APLF aprataxin and PNKP like factor
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARF6 ADP-ribosylation factor 6
ARL4D ADP-ribosylation factor-like 4D
ARMT1 acidic residue methyltransferase 1
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARR3 arrestin 3, retinal (X-arrestin)
ART3 ADP-ribosyltransferase 3
ASB17 ankyrin repeat and SOCS box containing 17
ASMT acetylserotonin O-methyltransferase
ATG3 autophagy related 3
AXDND1 axonemal dynein light chain domain containing 1
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
BCDIN3D BCDIN3 domain containing
BCL2A1 BCL2-related protein A1
BDKRB2 bradykinin receptor B2
BEX1 brain expressed, X-linked 1
BHMT betaine--homocysteine S-methyltransferase
BICC1 BicC family RNA binding protein 1
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2
BPI bactericidal/permeability-increasing protein
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
C12ORF40 chromosome 12 open reading frame 40
C14ORF142 chromosome 14 open reading frame 142
C15ORF59 chromosome 15 open reading frame 59
C1D C1D nuclear receptor corepressor
C1ORF162 chromosome 1 open reading frame 162
C3AR1 complement component 3a receptor 1
C4ORF22 chromosome 4 open reading frame 22
C6ORF203 chromosome 6 open reading frame 203
C6ORF58 chromosome 6 open reading frame 58
CACYBP calcyclin binding protein
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CASC1 cancer susceptibility candidate 1
CAST calpastatin
CCDC126 coiled-coil domain containing 126
CCDC30 coiled-coil domain containing 30
CCL2 chemokine (C-C motif) ligand 2
CCL23 chemokine (C-C motif) ligand 23
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCL7 chemokine (C-C motif) ligand 7
CCPG1 cell cycle progression 1
CCR1 chemokine (C-C motif) receptor 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD101 CD101 molecule
CD200R1 CD200 receptor 1
CD300LB CD300 molecule-like family member b
CD93 CD93 molecule
CDA cytidine deaminase
CDC42 cell division cycle 42
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEP19 centrosomal protein 19kDa
CFC1B cripto, FRL-1, cryptic family 1B
CHMP3 charged multivesicular body protein 3
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CILP2 cartilage intermediate layer protein 2
CLC Charcot-Leyden crystal galectin
CLDN22 claudin 22
CLDN23 claudin 23
CNIH4 cornichon family AMPA receptor auxiliary protein 4
COA6 cytochrome c oxidase assembly factor 6
COL22A1 collagen, type XXII, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
COX17 COX17 cytochrome c oxidase copper chaperone
CPPED1 calcineurin-like phosphoesterase domain containing 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRISP3 cysteine-rich secretory protein 3
CS citrate synthase
CST6 cystatin E/M
CSTA cystatin A (stefin A)
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTSG cathepsin G
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYSTM1 cysteine-rich transmembrane module containing 1
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DEFB1 defensin, beta 1
DHFR dihydrofolate reductase
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMRT1 doublesex and mab-3 related transcription factor 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DRAM1 DNA-damage regulated autophagy modulator 1
DYSF dysferlin
ECE1 endothelin converting enzyme 1
EFHB EF-hand domain family, member B
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4E3 eukaryotic translation initiation factor 4E family member 3
ELF5 E74-like factor 5 (ets domain transcription factor)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXOSC3 exosome component 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM101B family with sequence similarity 101, member B
FAM110B family with sequence similarity 110, member B
FAM126A family with sequence similarity 126, member A
FAM135B family with sequence similarity 135, member B
FAM136BP family with sequence similarity 136, member B, pseudogene
FAM151B family with sequence similarity 151, member B
FAM20B family with sequence similarity 20, member B
FAM65B family with sequence similarity 65, member B
FANCD2OS FANCD2 opposite strand
FBP1 fructose-1,6-bisphosphatase 1
FBXL17 F-box and leucine-rich repeat protein 17
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGD4 FYVE, RhoGEF and PH domain containing 4
FLJ44635 TPT1-like protein
FOXD4L6 forkhead box D4-like 6
FPR2 formyl peptide receptor 2
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FSIP1 fibrous sheath interacting protein 1
GAPT GRB2-binding adaptor protein, transmembrane
GBP7 guanylate binding protein 7
GC group-specific component (vitamin D binding protein)
GCA grancalcin, EF-hand calcium binding protein
GK5 glycerol kinase 5 (putative)
GLIPR2 GLI pathogenesis-related 2
GLT8D2 glycosyltransferase 8 domain containing 2
GLTP glycolipid transfer protein
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPC4 glypican 4
GPHA2 glycoprotein hormone alpha 2
GPR160 G protein-coupled receptor 160
GPR65 G protein-coupled receptor 65
GRIA1 glutamate receptor, ionotropic, AMPA 1
GSKIP GSK3B interacting protein
GSR glutathione reductase
GUCY2C guanylate cyclase 2C
GYG1 glycogenin 1
GYG2 glycogenin 2
H3F3A H3 histone, family 3A
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HHLA2 HERV-H LTR-associating 2
HIPK2 homeodomain interacting protein kinase 2
HIST1H4C histone cluster 1, H4c
HMGN2 high mobility group nucleosomal binding domain 2
HNF4A hepatocyte nuclear factor 4, alpha
HNMT histamine N-methyltransferase
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
HOXA1 homeobox A1
HOXA10 homeobox A10
HOXA2 homeobox A2
HOXB7 homeobox B7
HOXB8 homeobox B8
HOXB9 homeobox B9
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene
IKBIP IKBKB interacting protein
IL22RA2 interleukin 22 receptor, alpha 2
IMPG1 interphotoreceptor matrix proteoglycan 1
IRS2 insulin receptor substrate 2
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1BP1 integrin beta 1 binding protein 1
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA1755 KIAA1755
KIF3B kinesin family member 3B
KRT15 keratin 15, type I
KRT23 keratin 23, type I
LARP7 La ribonucleoprotein domain family, member 7
LDHA lactate dehydrogenase A
LGALS3 lectin, galactoside-binding, soluble, 3
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00239 long intergenic non-protein coding RNA 239
LINC00244 long intergenic non-protein coding RNA 244
LINC00261 long intergenic non-protein coding RNA 261
LINC00523 long intergenic non-protein coding RNA 523
LINC00596 long intergenic non-protein coding RNA 596
LIPT1 lipoyltransferase 1
LOC283332 uncharacterized LOC283332
LOC653653 adaptor-related protein complex 1, sigma 2 subunit pseudogene
LPL lipoprotein lipase
LRRC58 leucine rich repeat containing 58
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LST1 leukocyte specific transcript 1
LTBP1 latent transforming growth factor beta binding protein 1
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MARCKS myristoylated alanine-rich protein kinase C substrate
MCTP1 multiple C2 domains, transmembrane 1
MCU mitochondrial calcium uniporter
MEGF9 multiple EGF-like-domains 9
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MGAM maltase-glucoamylase
MICU2 mitochondrial calcium uptake 2
MITD1 MIT, microtubule interacting and transport, domain containing 1
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
MPC1 mitochondrial pyruvate carrier 1
MPHOSPH6 M-phase phosphoprotein 6
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NANOG Nanog homeobox
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NCF2 neutrophil cytosolic factor 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NKAP NFKB activating protein
NLRC4 NLR family, CARD domain containing 4
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NRBF2 nuclear receptor binding factor 2
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
OGN osteoglycin
OOEP oocyte expressed protein
OR4D10 olfactory receptor, family 4, subfamily D, member 10
OR4D6 olfactory receptor, family 4, subfamily D, member 6
OR52B2 olfactory receptor, family 52, subfamily B, member 2
OR5A1 olfactory receptor, family 5, subfamily A, member 1
OR5AN1 olfactory receptor, family 5, subfamily AN, member 1
OR6C4 olfactory receptor, family 6, subfamily C, member 4
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OSTF1 osteoclast stimulating factor 1
PADI4 peptidyl arginine deiminase, type IV
PAQR8 progestin and adipoQ receptor family member VIII
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDLIM5 PDZ and LIM domain 5
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PDZD3 PDZ domain containing 3
PGAM1 phosphoglycerate mutase 1 (brain)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLA2G5 phospholipase A2, group V
PLEK pleckstrin
PNPLA1 patatin-like phospholipase domain containing 1
POFUT1 protein O-fucosyltransferase 1
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
PPP1R17 protein phosphatase 1, regulatory subunit 17
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PROK2 prokineticin 2
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PTGES prostaglandin E synthase
PTPRO protein tyrosine phosphatase, receptor type, O
PURA purine-rich element binding protein A
PXMP4 peroxisomal membrane protein 4, 24kDa
QRFPR pyroglutamylated RFamide peptide receptor
RAB27A RAB27A, member RAS oncogene family
RAB29 RAB29, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAD51C RAD51 paralog C
RALB v-ral simian leukemia viral oncogene homolog B
RAP1A RAP1A, member of RAS oncogene family
RASL11A RAS-like, family 11, member A
RBMS1 RNA binding motif, single stranded interacting protein 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS2 regulator of G-protein signaling 2
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RHOU ras homolog family member U
RMI2 RecQ mediated genome instability 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNASEH2C ribonuclease H2, subunit C
RNF112 ring finger protein 112
RNF14 ring finger protein 14
RNF141 ring finger protein 141
RNF24 ring finger protein 24
RNPEP arginyl aminopeptidase (aminopeptidase B)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPE ribulose-5-phosphate-3-epimerase
RPL10L ribosomal protein L10-like
RPL21P44 ribosomal protein L21 pseudogene 44
RPL31P11 ribosomal protein L31 pseudogene 11
RPP14 ribonuclease P/MRP 14kDa subunit
RPPH1 ribonuclease P RNA component H1
RWDD1 RWD domain containing 1
RXFP2 relaxin/insulin-like family peptide receptor 2
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
S100A3 S100 calcium binding protein A3
S100A5 S100 calcium binding protein A5
S100A9 S100 calcium binding protein A9
SCARNA10 small Cajal body-specific RNA 10
SCARNA7 small Cajal body-specific RNA 7
SCARNA8 small Cajal body-specific RNA 8
SCG5 secretogranin V
SEBOX SEBOX homeobox
SEC11A SEC11 homolog A (S. cerevisiae)
SEC62 SEC62 homolog (S. cerevisiae)
SENP8 SUMO/sentrin specific peptidase family member 8
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SFTPB surfactant protein B
SGK1 serum/glucocorticoid regulated kinase 1
SGMS2 sphingomyelin synthase 2
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
SHISA2 shisa family member 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SKAP2 src kinase associated phosphoprotein 2
SKINTL Skint-like, pseudogene
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC35A5 solute carrier family 35, member A5
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLURP1 secreted LY6/PLAUR domain containing 1
SMC1A structural maintenance of chromosomes 1A
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNORA12 small nucleolar RNA, H/ACA box 12
SNORA36A small nucleolar RNA, H/ACA box 36A
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNX10 sorting nexin 10
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPOPL speckle-type POZ protein-like
SRGN serglycin
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STBD1 starch binding domain 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
STS steroid sulfatase (microsomal), isozyme S
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae)
SZT2 seizure threshold 2 homolog (mouse)
TAC4 tachykinin 4 (hemokinin)
TGM3 transglutaminase 3
THAP1 THAP domain containing, apoptosis associated protein 1
THAP5 THAP domain containing 5
TIPIN TIMELESS interacting protein
TLR1 toll-like receptor 1
TLR8 toll-like receptor 8
TM4SF4 transmembrane 4 L six family member 4
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM154 transmembrane protein 154
TMEM169 transmembrane protein 169
TMEM252 transmembrane protein 252
TMEM30A transmembrane protein 30A
TMEM38A transmembrane protein 38A
TMOD3 tropomodulin 3 (ubiquitous)
TMPO thymopoietin
TMSB4XP8 thymosin beta 4, X-linked pseudogene 8
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TOR3A torsin family 3, member A
TP53INP2 tumor protein p53 inducible nuclear protein 2
TP63 tumor protein p63
TPTE2P1 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1
TRIB1 tribbles pseudokinase 1
TRIL TLR4 interactor with leucine-rich repeats
TSLP thymic stromal lymphopoietin
TTC27 tetratricopeptide repeat domain 27
TUBBP5 tubulin, beta pseudogene 5
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UCN2 urocortin 2
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3
UGT8 UDP glycosyltransferase 8
UPB1 ureidopropionase, beta
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VTN vitronectin
WBP4 WW domain binding protein 4
WIBG within bgcn homolog (Drosophila)
XG Xg blood group
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBTB44 zinc finger and BTB domain containing 44
ZCCHC9 zinc finger, CCHC domain containing 9
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF438 zinc finger protein 438

low expression

Symbol Name
ITFG2 integrin alpha FG-GAP repeat containing 2
KLHDC4 kelch domain containing 4
SFSWAP splicing factor, suppressor of white-apricot family
STAT5A signal transducer and activator of transcription 5A
TMEM120B transmembrane protein 120B
UBAP2L ubiquitin associated protein 2-like
WDR59 WD repeat domain 59
WDR70 WD repeat domain 70