Acute Lung Injury_Lung Tissue_GSE1871 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1871
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Genes

600 genes differentially expressed during Acute Lung Injury_Lung Tissue_GSE1871 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
SMAD2 SMAD family member 2 4.5529
PILRB paired immunoglobin-like type 2 receptor beta 4.10842
C8ORF76 chromosome 8 open reading frame 76 4.02421
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 3.97271
ALOX5AP arachidonate 5-lipoxygenase-activating protein 3.72808
JAK2 Janus kinase 2 3.56589
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like 3.42626
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 3.32095
LRRC8D leucine rich repeat containing 8 family, member D 3.31949
TMEM126A transmembrane protein 126A 3.29242
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.26003
ARG2 arginase 2 3.25316
AK2 adenylate kinase 2 3.22646
NFYA nuclear transcription factor Y, alpha 3.20177
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.14848
NARS asparaginyl-tRNA synthetase 3.00149
TLR2 toll-like receptor 2 2.98796
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 2.96637
FPR1 formyl peptide receptor 1 2.96278
GSPT1 G1 to S phase transition 1 2.92557
NINJ1 ninjurin 1 2.92521
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 2.89471
FBL fibrillarin 2.88274
CLN5 ceroid-lipofuscinosis, neuronal 5 2.85444
SURF4 surfeit 4 2.83454
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 2.80782
SKIL SKI-like proto-oncogene 2.78625
ACP2 acid phosphatase 2, lysosomal 2.75952
ARL14EP ADP-ribosylation factor-like 14 effector protein 2.73561
NCF2 neutrophil cytosolic factor 2 2.67102
SMAP2 small ArfGAP2 2.66884
RAB20 RAB20, member RAS oncogene family 2.65597
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.65462
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 2.6433
ADRBK1 adrenergic, beta, receptor kinase 1 2.62469
CDC34 cell division cycle 34 2.60807
SIGLEC9 sialic acid binding Ig-like lectin 9 2.56177
GPHN gephyrin 2.55334
MANF mesencephalic astrocyte-derived neurotrophic factor 2.52204
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.4834
BCL10 B-cell CLL/lymphoma 10 2.46069
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.45499
CANX calnexin 2.43895
ANKLE2 ankyrin repeat and LEM domain containing 2 2.43826
CHMP4B charged multivesicular body protein 4B 2.42348
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.3917
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.38352
SNX10 sorting nexin 10 2.37926
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.34722
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 2.34118
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 2.32879
SLC35F5 solute carrier family 35, member F5 2.28987
EMILIN2 elastin microfibril interfacer 2 2.23823
CD244 CD244 molecule, natural killer cell receptor 2B4 2.22861
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 2.1449
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 2.13769
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.1298
TMEM33 transmembrane protein 33 2.12616
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 2.12211
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 2.11708
CD274 CD274 molecule 2.0996
RHOG ras homolog family member G 2.0938
EXOC3L4 exocyst complex component 3-like 4 2.08256
APRT adenine phosphoribosyltransferase 2.07269
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 2.06985
CD300LD CD300 molecule-like family member d 2.05416
BIRC2 baculoviral IAP repeat containing 2 2.0505
EIF1AD eukaryotic translation initiation factor 1A domain containing 2.04034
TMEM208 transmembrane protein 208 2.03377
MAN1A1 mannosidase, alpha, class 1A, member 1 2.02607
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 2.01165
SGPL1 sphingosine-1-phosphate lyase 1 1.97809
POLR1D polymerase (RNA) I polypeptide D, 16kDa 1.97128
RPS9 ribosomal protein S9 1.96194
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 1.94849
GRWD1 glutamate-rich WD repeat containing 1 1.94044
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.93059
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 1.92757
SNX18 sorting nexin 18 1.92671
CTSZ cathepsin Z 1.92603
PRDX3 peroxiredoxin 3 1.91985
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 1.91183
IRAK3 interleukin-1 receptor-associated kinase 3 1.89967
CCNG1 cyclin G1 1.87562
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.85723
SET SET nuclear proto-oncogene 1.85621
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.85466
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.85344
FAS Fas cell surface death receptor 1.85282
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.85137
NCF1 neutrophil cytosolic factor 1 1.84876
FAM49B family with sequence similarity 49, member B 1.84569
AIDA axin interactor, dorsalization associated 1.84189
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.83663
THBS1 thrombospondin 1 1.8357
METAP1 methionyl aminopeptidase 1 1.8223
MED7 mediator complex subunit 7 1.80795
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.80584
PHF23 PHD finger protein 23 1.80002
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.79459
SYK spleen tyrosine kinase 1.7854
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 1.77891
TBRG1 transforming growth factor beta regulator 1 1.77435
SEC61G Sec61 gamma subunit 1.77432
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 1.77358
ORAI2 ORAI calcium release-activated calcium modulator 2 1.75389
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 1.75319
BET1 Bet1 golgi vesicular membrane trafficking protein 1.73729
TNIP1 TNFAIP3 interacting protein 1 1.73458
SNX20 sorting nexin 20 1.72523
NCF4 neutrophil cytosolic factor 4, 40kDa 1.72455
CD300C CD300c molecule 1.71695
TGM2 transglutaminase 2 1.70272
CDC42SE1 CDC42 small effector 1 1.70153
GDA guanine deaminase 1.7012
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 1.69739
RPL7L1 ribosomal protein L7-like 1 1.69629
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.69472
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.69372
SNAP23 synaptosomal-associated protein, 23kDa 1.69178
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.68537
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.68042
TRAPPC3 trafficking protein particle complex 3 1.67978
HBS1L HBS1-like translational GTPase 1.67559
MMP19 matrix metallopeptidase 19 1.66831
SCAMP2 secretory carrier membrane protein 2 1.66758
MRPS2 mitochondrial ribosomal protein S2 1.66334
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.65338
CSTB cystatin B (stefin B) 1.64297
MYD88 myeloid differentiation primary response 88 1.63956
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.63706
CSF1R colony stimulating factor 1 receptor 1.62917
PTGES prostaglandin E synthase 1.628
CKS2 CDC28 protein kinase regulatory subunit 2 1.62148
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase 1.61466
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 1.60325
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 1.5983
RAP1GAP2 RAP1 GTPase activating protein 2 1.59629
EIF5A eukaryotic translation initiation factor 5A 1.59589
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.59474
XBP1 X-box binding protein 1 1.59341
ARL8B ADP-ribosylation factor-like 8B 1.59227
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.58734
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 1.58358
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.58342
RPL12 ribosomal protein L12 1.57667
CKAP4 cytoskeleton-associated protein 4 1.56908
LHFPL2 lipoma HMGIC fusion partner-like 2 1.56696
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.56677
PHLDA1 pleckstrin homology-like domain, family A, member 1 1.56039
DCTN3 dynactin 3 (p22) 1.55568
AEN apoptosis enhancing nuclease 1.55533
APOBR apolipoprotein B receptor 1.55438
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.55362
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.54268
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.52538
EIF5 eukaryotic translation initiation factor 5 1.51357
OSMR oncostatin M receptor 1.51313
RBM34 RNA binding motif protein 34 1.50973
MAK16 MAK16 homolog (S. cerevisiae) 1.50294
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.50243
LAP3 leucine aminopeptidase 3 1.49933
CLTA clathrin, light chain A 1.49391
EVI2A ecotropic viral integration site 2A 1.4921
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1.48812
HSPA13 heat shock protein 70kDa family, member 13 1.48724
PLBD2 phospholipase B domain containing 2 1.4863
ZNF593 zinc finger protein 593 1.48281
C6ORF120 chromosome 6 open reading frame 120 1.47977
PHB2 prohibitin 2 1.47668
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 1.47605
RBM18 RNA binding motif protein 18 1.47597
CLEC4D C-type lectin domain family 4, member D 1.47325
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 1.46926
TRIM8 tripartite motif containing 8 1.4677
ABHD13 abhydrolase domain containing 13 1.46633
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1.463
LPXN leupaxin 1.46107
GRK6 G protein-coupled receptor kinase 6 1.4594
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1.45792
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.45055
MED29 mediator complex subunit 29 1.4474
CAPG capping protein (actin filament), gelsolin-like 1.44604
BCAP29 B-cell receptor-associated protein 29 1.43537
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.43402
PLAC8 placenta-specific 8 1.43217
UXT ubiquitously-expressed, prefoldin-like chaperone 1.43083
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.42435
MMP9 matrix metallopeptidase 9 1.42288
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 1.4227
DTX3L deltex 3 like, E3 ubiquitin ligase 1.42101
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 1.41723
GFER growth factor, augmenter of liver regeneration 1.39213
DNM2 dynamin 2 1.39198
PWP1 PWP1 homolog (S. cerevisiae) 1.38844
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.38322
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.38293
WBSCR16 Williams-Beuren syndrome chromosome region 16 1.38218
GOLGA5 golgin A5 1.37754
RSL1D1 ribosomal L1 domain containing 1 1.37748
FAIM Fas apoptotic inhibitory molecule 1.37455
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 1.3701
TAOK1 TAO kinase 1 1.36878
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.36447
BDKRB2 bradykinin receptor B2 1.36441
ARHGAP30 Rho GTPase activating protein 30 1.36146
PITPNA phosphatidylinositol transfer protein, alpha 1.35933
ZCCHC2 zinc finger, CCHC domain containing 2 1.3537
RTN4RL2 reticulon 4 receptor-like 2 1.34996
PCBP1 poly(rC) binding protein 1 1.34664
PGAM1 phosphoglycerate mutase 1 (brain) 1.3458
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 1.34468
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.34324
EBAG9 estrogen receptor binding site associated, antigen, 9 1.34172
TBRG4 transforming growth factor beta regulator 4 1.34072
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.3402
C1QBP complement component 1, q subcomponent binding protein 1.33697
HN1L hematological and neurological expressed 1-like 1.33689
POFUT2 protein O-fucosyltransferase 2 1.33513
TFE3 transcription factor binding to IGHM enhancer 3 1.33491
IER2 immediate early response 2 1.33169
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.32584
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 1.32239
FMNL2 formin-like 2 1.32089
PGLYRP1 peptidoglycan recognition protein 1 1.3197
CD300LF CD300 molecule-like family member f 1.31664
LDHA lactate dehydrogenase A 1.31594
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 1.31393
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.29974
CTSC cathepsin C 1.29972
IGSF6 immunoglobulin superfamily, member 6 1.29787
PTPN6 protein tyrosine phosphatase, non-receptor type 6 1.29392
NUAK2 NUAK family, SNF1-like kinase, 2 1.29122
NFIL3 nuclear factor, interleukin 3 regulated 1.28927
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.28718
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 1.28378
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.28107
TCEA1 transcription elongation factor A (SII), 1 1.28087
PARP12 poly (ADP-ribose) polymerase family, member 12 1.27929
RPL24 ribosomal protein L24 1.27919
RPUSD1 RNA pseudouridylate synthase domain containing 1 1.27722
IRAK4 interleukin-1 receptor-associated kinase 4 1.2756
PLSCR1 phospholipid scramblase 1 1.27389
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.27216
CACUL1 CDK2-associated, cullin domain 1 1.25863
CTPS1 CTP synthase 1 1.25355
UBE2F ubiquitin-conjugating enzyme E2F (putative) 1.25297
RNF115 ring finger protein 115 1.25243
NVL nuclear VCP-like 1.24784
TLK2 tousled-like kinase 2 1.24537
PKM pyruvate kinase, muscle 1.24495
HMBS hydroxymethylbilane synthase 1.24202
BID BH3 interacting domain death agonist 1.24107
MBD1 methyl-CpG binding domain protein 1 1.2384
NBR1 neighbor of BRCA1 gene 1 1.23644
FYTTD1 forty-two-three domain containing 1 1.23619
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.23472
BASP1 brain abundant, membrane attached signal protein 1 1.22952
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.2237
SMNDC1 survival motor neuron domain containing 1 1.22231
PDPN podoplanin 1.22214
LYAR Ly1 antibody reactive 1.22211
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 1.21232
TRAPPC6B trafficking protein particle complex 6B 1.20974
TTC17 tetratricopeptide repeat domain 17 1.20737
EFHD2 EF-hand domain family, member D2 1.20648
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 1.20525
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 1.20439
TGFBI transforming growth factor, beta-induced, 68kDa 1.19988
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 1.19962
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 1.19682
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 1.19465
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.19261
TPD52 tumor protein D52 1.19192
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 1.19142
POMP proteasome maturation protein 1.18969
MRPS33 mitochondrial ribosomal protein S33 1.18613
EIF3A eukaryotic translation initiation factor 3, subunit A 1.17903
TMEM168 transmembrane protein 168 1.17704
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2 1.17678
RASGRP4 RAS guanyl releasing protein 4 1.17535
CSNK1G3 casein kinase 1, gamma 3 1.17433
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.17347
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 1.17278
CNOT7 CCR4-NOT transcription complex, subunit 7 1.17095
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.17084
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.16943
PLAUR plasminogen activator, urokinase receptor 1.16553
LYN LYN proto-oncogene, Src family tyrosine kinase 1.1618
PARP10 poly (ADP-ribose) polymerase family, member 10 1.16143
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 1.15987
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.15914
NOSIP nitric oxide synthase interacting protein 1.15263
EXOSC9 exosome component 9 1.1525
CD180 CD180 molecule 1.15207
C5AR1 complement component 5a receptor 1 1.14945
PPP1R18 protein phosphatase 1, regulatory subunit 18 1.14862
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 1.14846
MRPL52 mitochondrial ribosomal protein L52 1.14606
TAPBPL TAP binding protein-like 1.14041

decreased expression

Symbol Name Standardized Value
TMEM246 transmembrane protein 246 -4.52974
FGFR3 fibroblast growth factor receptor 3 -4.17487
PER3 period circadian clock 3 -4.08374
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -3.84031
NFYC nuclear transcription factor Y, gamma -3.77493
CADPS2 Ca++-dependent secretion activator 2 -3.75948
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -3.68972
EHBP1 EH domain binding protein 1 -3.45769
EIF4B eukaryotic translation initiation factor 4B -3.44279
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -3.31162
MIB2 mindbomb E3 ubiquitin protein ligase 2 -3.16157
AR androgen receptor -2.80598
LRRC20 leucine rich repeat containing 20 -2.72621
PRDM6 PR domain containing 6 -2.69629
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.68739
TMEM57 transmembrane protein 57 -2.67035
TMEM245 transmembrane protein 245 -2.58585
NRN1 neuritin 1 -2.57585
LPIN2 lipin 2 -2.54781
CLK2 CDC-like kinase 2 -2.52678
SGSH N-sulfoglucosamine sulfohydrolase -2.44455
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.44195
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -2.42998
ULK2 unc-51 like autophagy activating kinase 2 -2.421
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa -2.41986
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -2.41242
LACE1 lactation elevated 1 -2.39831
ADCK3 aarF domain containing kinase 3 -2.38231
ZNF395 zinc finger protein 395 -2.34941
BTBD2 BTB (POZ) domain containing 2 -2.32114
YPEL3 yippee-like 3 (Drosophila) -2.30866
TEP1 telomerase-associated protein 1 -2.26831
PNPLA6 patatin-like phospholipase domain containing 6 -2.26276
FGF16 fibroblast growth factor 16 -2.25797
NONO non-POU domain containing, octamer-binding -2.21983
WDR11 WD repeat domain 11 -2.20624
MAOB monoamine oxidase B -2.20081
ACVR2B activin A receptor, type IIB -2.17877
TAPT1 transmembrane anterior posterior transformation 1 -2.15227
C16ORF13 chromosome 16 open reading frame 13 -2.14759
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit -2.14628
ERGIC3 ERGIC and golgi 3 -2.11513
UIMC1 ubiquitin interaction motif containing 1 -2.09639
DOLPP1 dolichyldiphosphatase 1 -2.0895
RAB3IP RAB3A interacting protein -2.08071
RAB4A RAB4A, member RAS oncogene family -2.06183
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.04771
THRSP thyroid hormone responsive -2.03811
LCLAT1 lysocardiolipin acyltransferase 1 -2.0243
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) -2.02075
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -2.01051
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -2.00849
TM9SF3 transmembrane 9 superfamily member 3 -1.99568
CMC4 C-x(9)-C motif containing 4 -1.9854
PALMD palmdelphin -1.97722
AMACR alpha-methylacyl-CoA racemase -1.97382
KCTD15 potassium channel tetramerization domain containing 15 -1.95153
DDX26B DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B -1.94464
LIME1 Lck interacting transmembrane adaptor 1 -1.92061
MTUS1 microtubule associated tumor suppressor 1 -1.89818
PRRX1 paired related homeobox 1 -1.88693
MEGF6 multiple EGF-like-domains 6 -1.88619
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 -1.84931
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -1.83293
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -1.83223
RGL3 ral guanine nucleotide dissociation stimulator-like 3 -1.81855
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -1.81139
VSIG2 V-set and immunoglobulin domain containing 2 -1.79797
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -1.79527
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.78335
SUSD4 sushi domain containing 4 -1.78189
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 -1.78174
ACAA2 acetyl-CoA acyltransferase 2 -1.78156
TMEM132D transmembrane protein 132D -1.77974
IKBIP IKBKB interacting protein -1.77025
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -1.77024
COL14A1 collagen, type XIV, alpha 1 -1.75442
PSTK phosphoseryl-tRNA kinase -1.74506
ABHD4 abhydrolase domain containing 4 -1.7277
MARVELD1 MARVEL domain containing 1 -1.72549
ING2 inhibitor of growth family, member 2 -1.72246
CDK5 cyclin-dependent kinase 5 -1.70435
SIVA1 SIVA1, apoptosis-inducing factor -1.69899
MAST3 microtubule associated serine/threonine kinase 3 -1.69084
FAIM2 Fas apoptotic inhibitory molecule 2 -1.67938
ASPN asporin -1.6775
PBX3 pre-B-cell leukemia homeobox 3 -1.67647
SSBP3 single stranded DNA binding protein 3 -1.67454
ZDHHC14 zinc finger, DHHC-type containing 14 -1.64992
STX2 syntaxin 2 -1.63629
PGM2L1 phosphoglucomutase 2-like 1 -1.63486
DSTYK dual serine/threonine and tyrosine protein kinase -1.62506
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C -1.62369
BTBD3 BTB (POZ) domain containing 3 -1.61039
GKAP1 G kinase anchoring protein 1 -1.59269
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -1.59189
RANBP10 RAN binding protein 10 -1.57832
H2AFV H2A histone family, member V -1.57791
ZCCHC3 zinc finger, CCHC domain containing 3 -1.57144
BRCA2 breast cancer 2, early onset -1.56419
RERE arginine-glutamic acid dipeptide (RE) repeats -1.56297
TSHZ3 teashirt zinc finger homeobox 3 -1.56221
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -1.55674
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -1.54101
CUEDC1 CUE domain containing 1 -1.52366
KDR kinase insert domain receptor -1.51942
C12ORF57 chromosome 12 open reading frame 57 -1.5129
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -1.50983
MFSD6 major facilitator superfamily domain containing 6 -1.50494
CNTLN centlein, centrosomal protein -1.5025
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -1.4947
AKAP8L A kinase (PRKA) anchor protein 8-like -1.49343
S100A16 S100 calcium binding protein A16 -1.48705
E4F1 E4F transcription factor 1 -1.48332
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -1.47984
ALCAM activated leukocyte cell adhesion molecule -1.47358
ZNF726 zinc finger protein 726 -1.46994
TLE2 transducin-like enhancer of split 2 -1.46824
SETD1A SET domain containing 1A -1.46721
KLHL17 kelch-like family member 17 -1.4668
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -1.46221
PHKB phosphorylase kinase, beta -1.45138
ACYP1 acylphosphatase 1, erythrocyte (common) type -1.4416
CLCN3 chloride channel, voltage-sensitive 3 -1.43659
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -1.43636
ANAPC2 anaphase promoting complex subunit 2 -1.432
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -1.40372
RBM5 RNA binding motif protein 5 -1.38769
AKAP8 A kinase (PRKA) anchor protein 8 -1.38766
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 -1.38231
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.38201
DOCK4 dedicator of cytokinesis 4 -1.36234
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -1.36212
SNX27 sorting nexin family member 27 -1.35528
GPD1L glycerol-3-phosphate dehydrogenase 1-like -1.34862
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -1.34672
MXI1 MAX interactor 1, dimerization protein -1.34658
HOXB6 homeobox B6 -1.33607
CSNK1G2 casein kinase 1, gamma 2 -1.33445
SREBF1 sterol regulatory element binding transcription factor 1 -1.33105
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -1.32343
NCOA1 nuclear receptor coactivator 1 -1.3194
NADSYN1 NAD synthetase 1 -1.31769
ESYT2 extended synaptotagmin-like protein 2 -1.31215
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -1.31035
BTBD6 BTB (POZ) domain containing 6 -1.30226
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -1.3011
PRKCZ protein kinase C, zeta -1.30078
LPCAT1 lysophosphatidylcholine acyltransferase 1 -1.29548
CHPT1 choline phosphotransferase 1 -1.28562
DOPEY1 dopey family member 1 -1.27556
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like -1.27477
SSTR2 somatostatin receptor 2 -1.27246
E2F2 E2F transcription factor 2 -1.27079
NTF3 neurotrophin 3 -1.26697
GSTM4 glutathione S-transferase mu 4 -1.26527
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -1.26511
TMEM150A transmembrane protein 150A -1.26472
PPIG peptidylprolyl isomerase G (cyclophilin G) -1.26405
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -1.26091
ZNF579 zinc finger protein 579 -1.25927
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -1.25695
NDN necdin, melanoma antigen (MAGE) family member -1.25028
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -1.24825
UCKL1 uridine-cytidine kinase 1-like 1 -1.24652
ULK1 unc-51 like autophagy activating kinase 1 -1.24356
USP21 ubiquitin specific peptidase 21 -1.24109
CD99L2 CD99 molecule-like 2 -1.23912
NENF neudesin neurotrophic factor -1.23861
CBX7 chromobox homolog 7 -1.23855
DAD1 defender against cell death 1 -1.23644
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -1.23465
CBX6 chromobox homolog 6 -1.23253
CC2D2A coiled-coil and C2 domain containing 2A -1.22923
MYH14 myosin, heavy chain 14, non-muscle -1.22852
MRPS9 mitochondrial ribosomal protein S9 -1.22822
SRPK2 SRSF protein kinase 2 -1.22524
IVD isovaleryl-CoA dehydrogenase -1.21238
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -1.20667
RGS3 regulator of G-protein signaling 3 -1.19982
RAP1GAP RAP1 GTPase activating protein -1.18945
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha -1.18664
LRRC45 leucine rich repeat containing 45 -1.18608
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -1.18454
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -1.18188
ZSCAN21 zinc finger and SCAN domain containing 21 -1.18004
C14ORF159 chromosome 14 open reading frame 159 -1.17717
DTNA dystrobrevin, alpha -1.177
IGSF3 immunoglobulin superfamily, member 3 -1.1764
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -1.17571
OCIAD2 OCIA domain containing 2 -1.16993
ZNF821 zinc finger protein 821 -1.16977
LMBRD1 LMBR1 domain containing 1 -1.16648
C11ORF95 chromosome 11 open reading frame 95 -1.16113
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -1.15967
PAQR6 progestin and adipoQ receptor family member VI -1.1543
TMEM132A transmembrane protein 132A -1.15419
EDC3 enhancer of mRNA decapping 3 -1.15348
FADS1 fatty acid desaturase 1 -1.14957
MSL1 male-specific lethal 1 homolog (Drosophila) -1.14765
BACE1 beta-site APP-cleaving enzyme 1 -1.14559
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -1.14366
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -1.13561
PPA2 pyrophosphatase (inorganic) 2 -1.1344
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -1.13417
ZMAT5 zinc finger, matrin-type 5 -1.12775
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -1.12735
RPA3 replication protein A3, 14kDa -1.12044
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase -1.11675
UNC5C unc-5 homolog C (C. elegans) -1.11586
RNF215 ring finger protein 215 -1.11099
RC3H1 ring finger and CCCH-type domains 1 -1.11029
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -1.10384
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 -1.10172
PHLDB1 pleckstrin homology-like domain, family B, member 1 -1.09774
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.09506
PKN3 protein kinase N3 -1.09477
CRAMP1L Crm, cramped-like (Drosophila) -1.09366
RBM28 RNA binding motif protein 28 -1.09232
FMO5 flavin containing monooxygenase 5 -1.09111
PPAP2B phosphatidic acid phosphatase type 2B -1.08943
IRF6 interferon regulatory factor 6 -1.0885
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -1.08631
VANGL2 VANGL planar cell polarity protein 2 -1.08526
ITPKB inositol-trisphosphate 3-kinase B -1.08294
SESTD1 SEC14 and spectrin domains 1 -1.08124
ZMYND11 zinc finger, MYND-type containing 11 -1.07788
NIT1 nitrilase 1 -1.07569
SLC38A5 solute carrier family 38, member 5 -1.07099
TBX21 T-box 21 -1.06871
MTA3 metastasis associated 1 family, member 3 -1.06699
NFIB nuclear factor I/B -1.06663
TMEM64 transmembrane protein 64 -1.06446
RALBP1 ralA binding protein 1 -1.0617
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -1.05564
PINK1 PTEN induced putative kinase 1 -1.05511
BIK BCL2-interacting killer (apoptosis-inducing) -1.05031
TBC1D30 TBC1 domain family, member 30 -1.05007
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -1.04819
ZNF280D zinc finger protein 280D -1.04577
MEOX2 mesenchyme homeobox 2 -1.04566
KHK ketohexokinase (fructokinase) -1.04315
PCSK5 proprotein convertase subtilisin/kexin type 5 -1.04312
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -1.04262
LIMCH1 LIM and calponin homology domains 1 -1.02941
FBXL12 F-box and leucine-rich repeat protein 12 -1.02646
FYCO1 FYVE and coiled-coil domain containing 1 -1.02603
NICN1 nicolin 1 -1.02453
GPR155 G protein-coupled receptor 155 -1.02174
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -1.02126
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -1.01934
GXYLT1 glucoside xylosyltransferase 1 -1.01926
BCAP31 B-cell receptor-associated protein 31 -1.01708
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) -1.0162
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -1.01459
SLCO5A1 solute carrier organic anion transporter family, member 5A1 -1.01448
HINT1 histidine triad nucleotide binding protein 1 -1.01294
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -1.01294
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 -1.01053
TTC28 tetratricopeptide repeat domain 28 -1.00796
KLF15 Kruppel-like factor 15 -1.00635
TEX2 testis expressed 2 -1.00612
SNX24 sorting nexin 24 -1.00506
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -1.00492
ACAT1 acetyl-CoA acetyltransferase 1 -1.00443
SECISBP2L SECIS binding protein 2-like -1.00331
THRA thyroid hormone receptor, alpha -1.00139
PRR12 proline rich 12 -0.997227
MFAP3L microfibrillar-associated protein 3-like -0.994664
TUFT1 tuftelin 1 -0.991709
PCBP2 poly(rC) binding protein 2 -0.991703
ROMO1 reactive oxygen species modulator 1 -0.988011
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -0.9831
CFL2 cofilin 2 (muscle) -0.982036
LIN52 lin-52 DREAM MuvB core complex component -0.981867
TMEM50A transmembrane protein 50A -0.981313
AIG1 androgen-induced 1 -0.97965
EPHA1 EPH receptor A1 -0.975879
JARID2 jumonji, AT rich interactive domain 2 -0.975653
TP53BP2 tumor protein p53 binding protein 2 -0.974942
APH1B APH1B gamma secretase subunit -0.970696
RAB3D RAB3D, member RAS oncogene family -0.969803
PAMR1 peptidase domain containing associated with muscle regeneration 1 -0.968983
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.968297
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -0.968189
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -0.967892
EXPH5 exophilin 5 -0.966463
TRRAP transformation/transcription domain-associated protein -0.962629
WDR6 WD repeat domain 6 -0.96087
FAM3C family with sequence similarity 3, member C -0.959616
CISD3 CDGSH iron sulfur domain 3 -0.959028
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.958635
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.954649
MCM7 minichromosome maintenance complex component 7 -0.954073
GAB1 GRB2-associated binding protein 1 -0.953533
MCM3AP minichromosome maintenance complex component 3 associated protein -0.953224
ACAD11 acyl-CoA dehydrogenase family, member 11 -0.952687
CNRIP1 cannabinoid receptor interacting protein 1 -0.95187
COL4A4 collagen, type IV, alpha 4 -0.951451
GRK4 G protein-coupled receptor kinase 4 -0.946699