Acute Lung Injury Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Acute lung injury (ALI) is a diffuse heterogeneous lung injury characterized by hypoxemia, non cardiogenic pulmonary edema, low lung compliance and widespread capillary leakage. ALI is caused by any stimulus of local or systemic inflammation, principally sepsis. (Experimental Factor Ontology, EFO_0004610)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D055371
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Genes

575 genes/proteins associated with the disease Acute Lung Injury from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
APOA1 apolipoprotein A-I 2.88009
IL1RL1 interleukin 1 receptor-like 1 2.88009
ASCL1 achaete-scute family bHLH transcription factor 1 2.88009
ICAM1 intercellular adhesion molecule 1 2.88009
TGFB1 transforming growth factor, beta 1 2.88009
VIP vasoactive intestinal peptide 2.88009
TXN thioredoxin 2.88009
FASLG Fas ligand (TNF superfamily, member 6) 2.88009
TFF1 trefoil factor 1 2.88009
TFF2 trefoil factor 2 2.88009
EDN1 endothelin 1 2.88009
MYLK myosin light chain kinase 2.88009
FAS Fas cell surface death receptor 2.88009
ACVR1 activin A receptor, type I 2.88009
PPARG peroxisome proliferator-activated receptor gamma 2.88009
CAT catalase 2.88009
TNF tumor necrosis factor 2.4778
IL6 interleukin 6 2.40809
IL1B interleukin 1, beta 2.40654
CXCL8 chemokine (C-X-C motif) ligand 8 2.35906
NOS2 nitric oxide synthase 2, inducible 2.34652
MMP9 matrix metallopeptidase 9 2.33271
CCL2 chemokine (C-C motif) ligand 2 2.3175
HMOX1 heme oxygenase 1 2.3088
MPO myeloperoxidase 2.29143
CCL3 chemokine (C-C motif) ligand 3 2.28216
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.24823
MAPK3 mitogen-activated protein kinase 3 2.2388
MAPK1 mitogen-activated protein kinase 1 2.23249
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.22254
JUN jun proto-oncogene 2.21222
SOD2 superoxide dismutase 2, mitochondrial 2.20515
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.19967
IFNG interferon, gamma 2.18331
BAX BCL2-associated X protein 2.17727
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.16465
TIMP1 TIMP metallopeptidase inhibitor 1 2.16194
FOS FBJ murine osteosarcoma viral oncogene homolog 2.12611
MMP2 matrix metallopeptidase 2 2.12286
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.10136
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.09179
NOS3 nitric oxide synthase 3 (endothelial cell) 2.07672
IL10 interleukin 10 2.07492
CXCL10 chemokine (C-X-C motif) ligand 10 2.07416
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.06822
CXCL2 chemokine (C-X-C motif) ligand 2 2.0671
IL12B interleukin 12B 2.04955
DDIT3 DNA-damage-inducible transcript 3 2.03899
COL1A1 collagen, type I, alpha 1 2.03676
VCAM1 vascular cell adhesion molecule 1 2.03521
CCL11 chemokine (C-C motif) ligand 11 2.02698
IL4 interleukin 4 2.02431
BCL2 B-cell CLL/lymphoma 2 2.00996
IL1A interleukin 1, alpha 2.00592
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.99907
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.99351
PARP1 poly (ADP-ribose) polymerase 1 1.98267
SOD1 superoxide dismutase 1, soluble 1.97799
GSR glutathione reductase 1.95585
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.95375
SFTPA1 surfactant protein A1 1.93643
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.92785
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.92674
TLR4 toll-like receptor 4 1.92548
TP53 tumor protein p53 1.92485
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.92265
CD86 CD86 molecule 1.90492
HSPA1A heat shock 70kDa protein 1A 1.89311
MAPK8 mitogen-activated protein kinase 8 1.89264
NFE2L2 nuclear factor, erythroid 2-like 2 1.8909
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.88737
CCL4 chemokine (C-C motif) ligand 4 1.88638
VEGFA vascular endothelial growth factor A 1.88589
ATF3 activating transcription factor 3 1.85799
IL18 interleukin 18 1.85764
CAV1 caveolin 1, caveolae protein, 22kDa 1.84976
EGFR epidermal growth factor receptor 1.84569
SFTPB surfactant protein B 1.84198
SPP1 secreted phosphoprotein 1 1.81484
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.80775
NQO1 NAD(P)H dehydrogenase, quinone 1 1.79981
MMP1 matrix metallopeptidase 1 1.78663
JUNB jun B proto-oncogene 1.78397
IL5 interleukin 5 1.77975
PLAT plasminogen activator, tissue 1.77975
STAT1 signal transducer and activator of transcription 1, 91kDa 1.77277
CCL5 chemokine (C-C motif) ligand 5 1.75993
PCNA proliferating cell nuclear antigen 1.75836
ARG1 arginase 1 1.75201
DUSP1 dual specificity phosphatase 1 1.75162
IL13 interleukin 13 1.74341
ALB albumin 1.74119
ANXA5 annexin A5 1.73373
FTH1 ferritin, heavy polypeptide 1 1.72988
ANGPTL4 angiopoietin-like 4 1.72199
GADD45A growth arrest and DNA-damage-inducible, alpha 1.72178
PPARA peroxisome proliferator-activated receptor alpha 1.71586
MMP13 matrix metallopeptidase 13 1.69638
LCN2 lipocalin 2 1.6874
CYCS cytochrome c, somatic 1.6874
LITAF lipopolysaccharide-induced TNF factor 1.68697
CLU clusterin 1.68549
CREB1 cAMP responsive element binding protein 1 1.68464
CCND1 cyclin D1 1.68379
GCLC glutamate-cysteine ligase, catalytic subunit 1.67804
EGR1 early growth response 1 1.67159
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.67051
MMP3 matrix metallopeptidase 3 1.67029
LEP leptin 1.66253
PDGFB platelet-derived growth factor beta polypeptide 1.65952
IGF1 insulin-like growth factor 1 (somatomedin C) 1.64797
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.63698
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.63473
TLR2 toll-like receptor 2 1.63473
BIRC3 baculoviral IAP repeat containing 3 1.63473
HSF1 heat shock transcription factor 1 1.6278
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.62713
MGST1 microsomal glutathione S-transferase 1 1.62129
COL3A1 collagen, type III, alpha 1 1.61736
GPX3 glutathione peroxidase 3 1.61552
NDRG1 N-myc downstream regulated 1 1.60781
SELE selectin E 1.60594
GSTM1 glutathione S-transferase mu 1 1.60571
APOE apolipoprotein E 1.60035
F3 coagulation factor III (thromboplastin, tissue factor) 1.59849
CAPN1 calpain 1, (mu/I) large subunit 1.59357
FGF2 fibroblast growth factor 2 (basic) 1.59311
CTSB cathepsin B 1.59125
HMGB1 high mobility group box 1 1.59054
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.58607
CH25H cholesterol 25-hydroxylase 1.58398
CD14 CD14 molecule 1.58065
IL2 interleukin 2 1.57924
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.57474
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.57378
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.56994
PECAM1 platelet/endothelial cell adhesion molecule 1 1.56533
SPHK1 sphingosine kinase 1 1.56239
CCL20 chemokine (C-C motif) ligand 20 1.56117
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.55451
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.55255
CD40 CD40 molecule, TNF receptor superfamily member 5 1.55231
S100A8 S100 calcium binding protein A8 1.54815
MAPK9 mitogen-activated protein kinase 9 1.54596
MT1A metallothionein 1A 1.54548
IGFBP3 insulin-like growth factor binding protein 3 1.54232
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.54062
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.53796
CYR61 cysteine-rich, angiogenic inducer, 61 1.52388
MAPK14 mitogen-activated protein kinase 14 1.52363
CTGF connective tissue growth factor 1.51456
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.50877
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.50877
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.50423
GPX1 glutathione peroxidase 1 1.50348
NCF1 neutrophil cytosolic factor 1 1.50069
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.49711
ARG2 arginase 2 1.49711
XBP1 X-box binding protein 1 1.49356
IL12A interleukin 12A 1.49148
ATF4 activating transcription factor 4 1.48428
BCL2L1 BCL2-like 1 1.48299
ACTB actin, beta 1.48273
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.4817
VCL vinculin 1.4817
CD44 CD44 molecule (Indian blood group) 1.47556
AQP3 aquaporin 3 (Gill blood group) 1.47556
GSTP1 glutathione S-transferase pi 1 1.47244
TIMP2 TIMP metallopeptidase inhibitor 2 1.47219
BIRC5 baculoviral IAP repeat containing 5 1.46986
FASN fatty acid synthase 1.46807
TAC1 tachykinin, precursor 1 1.46674
GSTA1 glutathione S-transferase alpha 1 1.46542
HSPB1 heat shock 27kDa protein 1 1.46542
IRF1 interferon regulatory factor 1 1.46409
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.46356
POR P450 (cytochrome) oxidoreductase 1.46146
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.46015
S100A9 S100 calcium binding protein A9 1.45962
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.45883
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.45697
BID BH3 interacting domain death agonist 1.45089
CD83 CD83 molecule 1.44681
ALOX5 arachidonate 5-lipoxygenase 1.44193
TIMP3 TIMP metallopeptidase inhibitor 3 1.43782
ATF6 activating transcription factor 6 1.43755
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.437
GCLM glutamate-cysteine ligase, modifier subunit 1.43673
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.43564
SMAD3 SMAD family member 3 1.43347
RHOA ras homolog family member A 1.4313
IL17A interleukin 17A 1.42885
THBD thrombomodulin 1.42885
FN1 fibronectin 1 1.42669
CHUK conserved helix-loop-helix ubiquitous kinase 1.42535
TGFA transforming growth factor, alpha 1.42508
SAA3P serum amyloid A3 pseudogene 1.42374
GADD45B growth arrest and DNA-damage-inducible, beta 1.42129
BDNF brain-derived neurotrophic factor 1.41368
HSPA8 heat shock 70kDa protein 8 1.41229
FST follistatin 1.41202
SRXN1 sulfiredoxin 1 1.41119
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.41119
CD36 CD36 molecule (thrombospondin receptor) 1.40623
GDF15 growth differentiation factor 15 1.40345
G6PD glucose-6-phosphate dehydrogenase 1.40176
HSPA1B heat shock 70kDa protein 1B 1.39952
GJA1 gap junction protein, alpha 1, 43kDa 1.39591
CD80 CD80 molecule 1.39086
LIF leukemia inhibitory factor 1.38835
GSK3B glycogen synthase kinase 3 beta 1.3878
TFRC transferrin receptor 1.38752
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.38641
CXCR4 chemokine (C-X-C motif) receptor 4 1.38441
ENO1 enolase 1, (alpha) 1.3827
SFTPD surfactant protein D 1.38071
PLAUR plasminogen activator, urokinase receptor 1.38071
NOX4 NADPH oxidase 4 1.37817
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.37619
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.3716
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.3699
LYN LYN proto-oncogene, Src family tyrosine kinase 1.3699
C3 complement component 3 1.3682
SCARB1 scavenger receptor class B, member 1 1.36648
TF transferrin 1.36648
CSF1R colony stimulating factor 1 receptor 1.36619
INHBA inhibin, beta A 1.36361
LPL lipoprotein lipase 1.36247
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.36247
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.36133
FOSL1 FOS-like antigen 1 1.35589
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.35415
COL1A2 collagen, type I, alpha 2 1.35271
SOD3 superoxide dismutase 3, extracellular 1.35184
BMP2 bone morphogenetic protein 2 1.35184
CXCL12 chemokine (C-X-C motif) ligand 12 1.35098
ACTA2 actin, alpha 2, smooth muscle, aorta 1.34926
CP ceruloplasmin (ferroxidase) 1.34752
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.34547
LBP lipopolysaccharide binding protein 1.34285
IGFBP5 insulin-like growth factor binding protein 5 1.34285
TJP1 tight junction protein 1 1.34285
AGER advanced glycosylation end product-specific receptor 1.33966
F2 coagulation factor II (thrombin) 1.33909
CREBBP CREB binding protein 1.3382
NOS1 nitric oxide synthase 1 (neuronal) 1.33434
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.33346
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.33257
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.33257
HBEGF heparin-binding EGF-like growth factor 1.33169
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.33169
TXNRD1 thioredoxin reductase 1 1.3314
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.32935
MT2A metallothionein 2A 1.32786
CXCL3 chemokine (C-X-C motif) ligand 3 1.32696
RXRA retinoid X receptor, alpha 1.32607
SIRT1 sirtuin 1 1.32458
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.3231
GLUL glutamate-ammonia ligase 1.32074
LDLR low density lipoprotein receptor 1.31985
APP amyloid beta (A4) precursor protein 1.31927
GSTM2 glutathione S-transferase mu 2 (muscle) 1.31506
IFNB1 interferon, beta 1, fibroblast 1.31476
MMP7 matrix metallopeptidase 7 1.31476
PTK2 protein tyrosine kinase 2 1.31237
THBS1 thrombospondin 1 1.31237
ANXA2 annexin A2 1.31237
CYBA cytochrome b-245, alpha polypeptide 1.3103
ADM adrenomedullin 1.3103
CYBB cytochrome b-245, beta polypeptide 1.30819
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.30819
MAP2K1 mitogen-activated protein kinase kinase 1 1.30574
FOSL2 FOS-like antigen 2 1.30574
CCNG1 cyclin G1 1.30208
NPPB natriuretic peptide B 1.30208
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.30087
PRDX1 peroxiredoxin 1 1.29996
BIRC2 baculoviral IAP repeat containing 2 1.29996
CKS2 CDC28 protein kinase regulatory subunit 2 1.29996
IER3 immediate early response 3 1.29595
IL6ST interleukin 6 signal transducer 1.2941
IRS1 insulin receptor substrate 1 1.2941
PON1 paraoxonase 1 1.29225
CSF1 colony stimulating factor 1 (macrophage) 1.29133
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.29072
BAD BCL2-associated agonist of cell death 1.29072
CD8A CD8a molecule 1.29072
ANXA1 annexin A1 1.29011
MAP2K6 mitogen-activated protein kinase kinase 6 1.28858
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.28425
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.28303
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.2821
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.2821
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.27502
CCL17 chemokine (C-C motif) ligand 17 1.27409
CXCL5 chemokine (C-X-C motif) ligand 5 1.27224
TGFB3 transforming growth factor, beta 3 1.26978
ODC1 ornithine decarboxylase 1 1.26359
STAR steroidogenic acute regulatory protein 1.26205
HDAC1 histone deacetylase 1 1.26205
E2F1 E2F transcription factor 1 1.26175
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.25807
PLIN2 perilipin 2 1.25713
G0S2 G0/G1 switch 2 1.25713
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.25682
MAPT microtubule-associated protein tau 1.25619
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.25463
TH tyrosine hydroxylase 1.25276
OCLN occludin 1.25214
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.25121
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.2509
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.25059
LHB luteinizing hormone beta polypeptide 1.24465
COL5A1 collagen, type V, alpha 1 1.2437
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.24213
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.23743
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.23712
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.23616
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.23296
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.23042
AQP1 aquaporin 1 (Colton blood group) 1.23042
FLT1 fms-related tyrosine kinase 1 1.23042
RB1 retinoblastoma 1 1.22979
GNAS GNAS complex locus 1.22821
GFAP glial fibrillary acidic protein 1.22371
TPM1 tropomyosin 1 (alpha) 1.22371
PLAU plasminogen activator, urokinase 1.22371
FOXO3 forkhead box O3 1.22112
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.22048
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.22048
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.21887
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.21855
PRDX2 peroxiredoxin 2 1.21695
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.21663
SDC2 syndecan 2 1.21567
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.21567
CCL7 chemokine (C-C motif) ligand 7 1.21468
GADD45G growth arrest and DNA-damage-inducible, gamma 1.21468
KLF6 Kruppel-like factor 6 1.21435
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.21076
EDNRA endothelin receptor type A 1.21011
ADRB2 adrenoceptor beta 2, surface 1.20913
TGIF1 TGFB-induced factor homeobox 1 1.20913
KDR kinase insert domain receptor 1.20751
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.20427
COMT catechol-O-methyltransferase 1.20427
STAT5A signal transducer and activator of transcription 5A 1.20262
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.199
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.19704
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.19704
CALCA calcitonin-related polypeptide alpha 1.19639
LTA lymphotoxin alpha 1.19639
RGS4 regulator of G-protein signaling 4 1.19312
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.19279
INS insulin 1.19246
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.19014
CRP C-reactive protein, pentraxin-related 1.18882
CDK1 cyclin-dependent kinase 1 1.18751
NGF nerve growth factor (beta polypeptide) 1.18718
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.18685
APAF1 apoptotic peptidase activating factor 1 1.18652
EPO erythropoietin 1.18652
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.18587
MKI67 marker of proliferation Ki-67 1.18587
EPHX2 epoxide hydrolase 2, cytoplasmic 1.18456
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.18093
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.17827
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.17827
JAK2 Janus kinase 2 1.17827
IDO1 indoleamine 2,3-dioxygenase 1 1.17728
SOX9 SRY (sex determining region Y)-box 9 1.17497
HK2 hexokinase 2 1.17497
TGM2 transglutaminase 2 1.17431
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.17034
CRH corticotropin releasing hormone 1.16866
CFLAR CASP8 and FADD-like apoptosis regulator 1.16833
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.16633
CSF3 colony stimulating factor 3 (granulocyte) 1.16467
NPPA natriuretic peptide A 1.16401
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 1.16335
ACO1 aconitase 1, soluble 1.16104
IL1R2 interleukin 1 receptor, type II 1.1607
IRS2 insulin receptor substrate 2 1.1607
CASP10 caspase 10, apoptosis-related cysteine peptidase 1.15899
CTF1 cardiotrophin 1 1.15865
SESN2 sestrin 2 1.15797
MCL1 myeloid cell leukemia 1 1.15695
P4HB prolyl 4-hydroxylase, beta polypeptide 1.15526
SREBF1 sterol regulatory element binding transcription factor 1 1.15526
PHGDH phosphoglycerate dehydrogenase 1.15526
IRAK2 interleukin-1 receptor-associated kinase 2 1.15425
OTC ornithine carbamoyltransferase 1.15425
PLA1A phospholipase A1 member A 1.15425
TGFB2 transforming growth factor, beta 2 1.15324
VDAC1 voltage-dependent anion channel 1 1.15256
S100B S100 calcium binding protein B 1.15256
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.15122
COX1 1.14989
MYD88 myeloid differentiation primary response 88 1.14989
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.14954
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.14954
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.1485
ADIPOQ adiponectin, C1Q and collagen domain containing 1.14713
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.14713
FZD2 frizzled class receptor 2 1.14575
PTGES prostaglandin E synthase 1.14438
SGK1 serum/glucocorticoid regulated kinase 1 1.142
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.142
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.14166
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.14132
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.13929
TTR transthyretin 1.13827
SFTPC surfactant protein C 1.13724
SIRPA signal-regulatory protein alpha 1.13724
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.13655
TSPO translocator protein (18kDa) 1.13381
GHR growth hormone receptor 1.13143
GCK glucokinase (hexokinase 4) 1.13143
KRAS Kirsten rat sarcoma viral oncogene homolog 1.13109
IGFBP1 insulin-like growth factor binding protein 1 1.13109
GSTM3 glutathione S-transferase mu 3 (brain) 1.1294
CCNB1 cyclin B1 1.12906
DIABLO diablo, IAP-binding mitochondrial protein 1.12872
CPT1A carnitine palmitoyltransferase 1A (liver) 1.12426
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.12426
HNF4A hepatocyte nuclear factor 4, alpha 1.12391
CCNE1 cyclin E1 1.12185
ELOVL6 ELOVL fatty acid elongase 6 1.12151
GSN gelsolin 1.12151
CCR2 chemokine (C-C motif) receptor 2 1.12151
BHLHE40 basic helix-loop-helix family, member e40 1.12151
KLF4 Kruppel-like factor 4 (gut) 1.12117
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.12082
IL2RA interleukin 2 receptor, alpha 1.11911
FOXO1 forkhead box O1 1.11877
ERCC1 excision repair cross-complementation group 1 1.11877
DDIT4 DNA-damage-inducible transcript 4 1.11741
ATF2 activating transcription factor 2 1.11673
FABP4 fatty acid binding protein 4, adipocyte 1.11571
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.11396
CCKBR cholecystokinin B receptor 1.11325
TLR3 toll-like receptor 3 1.11325
CTSD cathepsin D 1.1122
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.11151
IFRD1 interferon-related developmental regulator 1 1.11151
B2M beta-2-microglobulin 1.11151
SQSTM1 sequestosome 1 1.11046
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.10942
NAMPT nicotinamide phosphoribosyltransferase 1.10907
PRDX6 peroxiredoxin 6 1.10907
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.10734
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.10734
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.10699
SMAD1 SMAD family member 1 1.10596
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.10459
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.10459
PRKCD protein kinase C, delta 1.10246
NOTCH1 notch 1 1.10211
ZFP36 ZFP36 ring finger protein 1.10211
HSPE1 heat shock 10kDa protein 1 1.10211
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.10175
INSR insulin receptor 1.09998
IL4R interleukin 4 receptor 1.09857
PLTP phospholipid transfer protein 1.09857
ELN elastin 1.09857
FMO1 flavin containing monooxygenase 1 1.09751
BGLAP bone gamma-carboxyglutamate (gla) protein 1.09541
GCH1 GTP cyclohydrolase 1 1.09506
F2R coagulation factor II (thrombin) receptor 1.09506
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.09506
TAGLN transgelin 1.09297
IL3 interleukin 3 1.09154
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.09047
CTSL cathepsin L 1.08833
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.08797
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.08762
BMP6 bone morphogenetic protein 6 1.08442
MAP2K3 mitogen-activated protein kinase kinase 3 1.08407
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.08196
HMOX2 heme oxygenase 2 1.08126
MUC1 mucin 1, cell surface associated 1.08091
HSPA1L heat shock 70kDa protein 1-like 1.08091
TXN2 thioredoxin 2 1.08091
ACACB acetyl-CoA carboxylase beta 1.07768
G6PC glucose-6-phosphatase, catalytic subunit 1.07518
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.07411
PF4 platelet factor 4 1.07411
DBP D site of albumin promoter (albumin D-box) binding protein 1.07093
PRKCA protein kinase C, alpha 1.07093
JUND jun D proto-oncogene 1.07093
AGTR2 angiotensin II receptor, type 2 1.07093
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.06952
LGALS3 lectin, galactoside-binding, soluble, 3 1.06881
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.06881
ANPEP alanyl (membrane) aminopeptidase 1.06771
EGLN3 egl-9 family hypoxia-inducible factor 3 1.06771
GSTT1 glutathione S-transferase theta 1 1.06771
GSTA3 glutathione S-transferase alpha 3 1.06771
FSHB follicle stimulating hormone, beta polypeptide 1.06333
TBX21 T-box 21 1.05936
GCGR glucagon receptor 1.059
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.05828
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.05828
AKAP12 A kinase (PRKA) anchor protein 12 1.05793
SYP synaptophysin 1.05793
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.05498
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.052
CSTB cystatin B (stefin B) 1.05163
PROS1 protein S (alpha) 1.05163
GPX2 glutathione peroxidase 2 1.05015
KLF2 Kruppel-like factor 2 1.04831
EIF5 eukaryotic translation initiation factor 5 1.04538
FKBP4 FK506 binding protein 4, 59kDa 1.04538
GBP2 guanylate binding protein 2, interferon-inducible 1.04538
ADCY6 adenylate cyclase 6 1.04276
CALCRL calcitonin receptor-like 1.04276
FETUB fetuin B 1.04276
CXCL16 chemokine (C-X-C motif) ligand 16 1.04239
VIM vimentin 1.03864
XDH xanthine dehydrogenase 1.03864
FABP1 fatty acid binding protein 1, liver 1.03789
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 1.03752
S1PR3 sphingosine-1-phosphate receptor 3 1.03715
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.03641
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.03604
KEAP1 kelch-like ECH-associated protein 1 1.03604
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.03419
GH1 growth hormone 1 1.03419
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.03308
HRAS Harvey rat sarcoma viral oncogene homolog 1.03308
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 1.03235
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.03197
TACR1 tachykinin receptor 1 1.03084
TFAM transcription factor A, mitochondrial 1.03046
CFB complement factor B 1.03046
ASS1 argininosuccinate synthase 1 1.03046
IGF2 insulin-like growth factor 2 1.02821
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.02821
CCNB2 cyclin B2 1.02634
CCND3 cyclin D3 1.02634
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.02485
SELENBP1 selenium binding protein 1 1.02485
FYN FYN proto-oncogene, Src family tyrosine kinase 1.02447
CD28 CD28 molecule 1.02225
LTC4S leukotriene C4 synthase 1.02225
CCR6 chemokine (C-C motif) receptor 6 1.02225
TUBA1A tubulin, alpha 1a 1.02188
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.02188
CAPN2 calpain 2, (m/II) large subunit 1.02188
VEGFC vascular endothelial growth factor C 1.02188
TAT tyrosine aminotransferase 1.02188
AR androgen receptor 1.0204
ALDOC aldolase C, fructose-bisphosphate 1.0189
EDNRB endothelin receptor type B 1.0189
HAMP hepcidin antimicrobial peptide 1.0189
CHEK2 checkpoint kinase 2 1.0189
CLCA1 chloride channel accessory 1 1.01776
SAA2 serum amyloid A2 1.01739
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.01701
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.01701
DUSP5 dual specificity phosphatase 5 1.01625
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.01625
IL11 interleukin 11 1.01625
HSPA2 heat shock 70kDa protein 2 1.01625
EP300 E1A binding protein p300 1.01587
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.01324
EI24 etoposide induced 2.4 1.01286
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.01286
BLNK B-cell linker 1.01249
CDK4 cyclin-dependent kinase 4 1.01137
SOCS3 suppressor of cytokine signaling 3 1.01137
LDHB lactate dehydrogenase B 1.01062
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.01062
SOCS2 suppressor of cytokine signaling 2 1.01062
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.01062