Acute Kidney Injury Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Sudden loss of renal function, as manifested by decreased urine production, and a rise in serum creatinine or blood urea nitrogen concentration (azotemia). (Human Phenotype Ontology, HP_0001919)
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Genes

21 genes associated with the Acute Kidney Injury phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
APOE apolipoprotein E
BCL2 B-cell CLL/lymphoma 2
COMT catechol-O-methyltransferase
CXCL8 chemokine (C-X-C motif) ligand 8
EPO erythropoietin
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
IL10 interleukin 10
IL6 interleukin 6
KLK1 kallikrein 1
LTA lymphotoxin alpha
MPO myeloperoxidase
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SUFU suppressor of fused homolog (Drosophila)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A