Acute Coronary Syndrome Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A disorder characterized by signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction. (Experimental Factor Ontology, EFO_0005672)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D054058
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Genes

57 genes/proteins associated with the disease Acute Coronary Syndrome from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 2.88009
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.88009
TPM4 tropomyosin 4 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
CKB creatine kinase, brain 2.88009
RAB7B RAB7B, member RAS oncogene family 2.88009
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.88009
CAPZB capping protein (actin filament) muscle Z-line, beta 2.88009
GSTP1 glutathione S-transferase pi 1 2.88009
TUBB1 tubulin, beta 1 class VI 2.88009
TNNT2 troponin T type 2 (cardiac) 2.88009
TNNI3 troponin I type 3 (cardiac) 2.88009
GSN gelsolin 2.88009
TLR4 toll-like receptor 4 2.88009
CKM creatine kinase, muscle 2.88009
VIM vimentin 2.88009
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.88009
LDHB lactate dehydrogenase B 2.88009
ACTG1 actin gamma 1 2.88009
PDIA3 protein disulfide isomerase family A, member 3 2.88009
VCL vinculin 2.88009
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.88009
TNF tumor necrosis factor 2.88009
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.88009
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
TUBA1C tubulin, alpha 1c 2.88009
ENO1 enolase 1, (alpha) 2.88009
MMP9 matrix metallopeptidase 9 2.88009
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.88009
F2 coagulation factor II (thrombin) 1.50172
IL6 interleukin 6 1.48376
TGFB1 transforming growth factor, beta 1 1.4794
MMP2 matrix metallopeptidase 2 1.42047
FOS FBJ murine osteosarcoma viral oncogene homolog 1.37418
FAS Fas cell surface death receptor 1.36876
NOS2 nitric oxide synthase 2, inducible 1.2821
VEGFA vascular endothelial growth factor A 1.26052
IL1B interleukin 1, beta 1.19672
CXCL8 chemokine (C-X-C motif) ligand 8 1.17497
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.16434
JUN jun proto-oncogene 1.16104
MAPK1 mitogen-activated protein kinase 1 1.16001
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.15593
EGR1 early growth response 1 1.15526
EDN1 endothelin 1 1.13963
MPO myeloperoxidase 1.13347
BCL2 B-cell CLL/lymphoma 2 1.13211
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.12082
IFNG interferon, gamma 1.11639
CAT catalase 1.10872
THBS1 thrombospondin 1 1.09436
CCL2 chemokine (C-C motif) ligand 2 1.08266
MAPK3 mitogen-activated protein kinase 3 1.08091
COL1A1 collagen, type I, alpha 1 1.06952
BCL2L1 BCL2-like 1 1.05423
TIMP2 TIMP metallopeptidase inhibitor 2 1.02858