Acromegaly Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A disease of metabolism that has_material_basis_in excessive growth hormone production which results_in enlargement located_in limb. (Human Disease Ontology, DOID_2449)
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Genes

19 genes associated with the Acromegaly phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIP aryl hydrocarbon receptor interacting protein
APOE apolipoprotein E
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
GHR growth hormone receptor
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
OGG1 8-oxoguanine DNA glycosylase
PDE11A phosphodiesterase 11A
SSTR2 somatostatin receptor 2
SSTR5 somatostatin receptor 5
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1