Acquired Immunodeficiency Syndrome Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per ┬ÁL of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS. (Human Disease Ontology, DOID_635)
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Genes

9 genes associated with the trait Acquired Immunodeficiency Syndrome in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
HCP5 HLA complex P5 (non-protein coding) 1.36815
PARD3B par-3 family cell polarity regulator beta 0.820059
ZNRD1 zinc ribbon domain containing 1 0.552134
DGKI diacylglycerol kinase, iota 0.539181
SOX5 SRY (sex determining region Y)-box 5 0.443956
NBPF15 neuroblastoma breakpoint family, member 15 0.443956
DOC2B double C2-like domains, beta 0.378873
RXRG retinoid X receptor, gamma 0.378873
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 0.323533