ATM pathway Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
Description The p53-dependent pathway of G1 arrest in response to damaged DNA. (Pathway Ontology, PW_0000303)
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34 proteins participating in the ATM pathway pathway from the PID Pathways dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ATM ATM serine/threonine kinase
BID BH3 interacting domain death agonist
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CHEK2 checkpoint kinase 2
CTBP1 C-terminal binding protein 1
DCLRE1C DNA cross-link repair 1C
FAM175A family with sequence similarity 175, member A
FANCD2 Fanconi anemia, complementation group D2
H2AFX H2A histone family, member X
KAT5 K(lysine) acetyltransferase 5
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NBN nibrin
RAD17 RAD17 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RBBP8 retinoblastoma binding protein 8
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
TERF2 telomeric repeat binding factor 2
TOP3A topoisomerase (DNA) III alpha
TP53BP1 tumor protein p53 binding protein 1
TRIM28 tripartite motif containing 28
UBE2N ubiquitin-conjugating enzyme E2N
UIMC1 ubiquitin interaction motif containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta