AML - Acute myeloid leukemia_Mononuclear Leukocyte_GSE2191 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2191
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Genes

600 genes differentially expressed during AML - Acute myeloid leukemia_Mononuclear Leukocyte_GSE2191 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ZC3H15 zinc finger CCCH-type containing 15 0.829911
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 0.816194
PABPC1 poly(A) binding protein, cytoplasmic 1 0.812596
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.777382
SSB Sjogren syndrome antigen B (autoantigen La) 0.727679
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.723449
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.721566
BCLAF1 BCL2-associated transcription factor 1 0.703618
TMED5 transmembrane emp24 protein transport domain containing 5 0.695406
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.656709
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 0.605014
KTN1 kinectin 1 (kinesin receptor) 0.584326
DEK DEK proto-oncogene 0.567882
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 0.558746
NUBP1 nucleotide binding protein 1 0.558383
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.55225
EIF3E eukaryotic translation initiation factor 3, subunit E 0.544373
SRSF11 serine/arginine-rich splicing factor 11 0.538317
COPS2 COP9 signalosome subunit 2 0.526454
RNF6 ring finger protein (C3H2C3 type) 6 0.516927
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.514723
SH3BGRL SH3 domain binding glutamate-rich protein like 0.475222
EBAG9 estrogen receptor binding site associated, antigen, 9 0.465865
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.450096
NIPBL Nipped-B homolog (Drosophila) 0.448634
COPS5 COP9 signalosome subunit 5 0.440829
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.438365
NMI N-myc (and STAT) interactor 0.436166
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.433876
EIF3M eukaryotic translation initiation factor 3, subunit M 0.429941
RPS24 ribosomal protein S24 0.425204
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 0.417692
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.415875
SUB1 SUB1 homolog (S. cerevisiae) 0.414066
RPL7 ribosomal protein L7 0.413728
COPB1 coatomer protein complex, subunit beta 1 0.41351
BMS1 BMS1 ribosome biogenesis factor 0.412595
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.41209
UBXN4 UBX domain protein 4 0.395515
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.393538
HTATSF1 HIV-1 Tat specific factor 1 0.391512
EIF6 eukaryotic translation initiation factor 6 0.386108
ANKRD12 ankyrin repeat domain 12 0.385979
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.384656
PNISR PNN-interacting serine/arginine-rich protein 0.38415
ZBTB11 zinc finger and BTB domain containing 11 0.382441
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.379231
NBN nibrin 0.378522
SRP72 signal recognition particle 72kDa 0.371381
PSME4 proteasome (prosome, macropain) activator subunit 4 0.371026
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.364645
NACA nascent polypeptide-associated complex alpha subunit 0.362672
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 0.357309
PTEN phosphatase and tensin homolog 0.357266
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.352376
ZNF451 zinc finger protein 451 0.351763
KIAA1033 KIAA1033 0.351713
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.348109
MORC3 MORC family CW-type zinc finger 3 0.347629
MBNL1 muscleblind-like splicing regulator 1 0.345909
STXBP3 syntaxin binding protein 3 0.336908
ZZZ3 zinc finger, ZZ-type containing 3 0.333657
UQCRB ubiquinol-cytochrome c reductase binding protein 0.331608
LOC100129361 0.330825
ZMYM2 zinc finger, MYM-type 2 0.328706
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 0.328407
TUG1 taurine up-regulated 1 (non-protein coding) 0.328043
RBM39 RNA binding motif protein 39 0.322172
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.319621
MAPK6 mitogen-activated protein kinase 6 0.316954
SNRPB2 small nuclear ribonucleoprotein polypeptide B 0.31496
SRSF6 serine/arginine-rich splicing factor 6 0.3144
LARP7 La ribonucleoprotein domain family, member 7 0.310246
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.309957
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.309073
CLASRP CLK4-associating serine/arginine rich protein 0.308149
FCHO1 FCH domain only 1 0.307095
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.306901
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.303699
XPO1 exportin 1 0.302745
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.302336
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 0.298209
SRP19 signal recognition particle 19kDa 0.297925
EIF4A2 eukaryotic translation initiation factor 4A2 0.293065
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.291488
RPL17 ribosomal protein L17 0.290899
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.29063
FRG1 FSHD region gene 1 0.29007
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.289638
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 0.289632
CHD9 chromodomain helicase DNA binding protein 9 0.288509
SNX2 sorting nexin 2 0.285908
TCERG1 transcription elongation regulator 1 0.284806
ZNF337 zinc finger protein 337 0.284028
THUMPD1 THUMP domain containing 1 0.282563
FIG4 FIG4 phosphoinositide 5-phosphatase 0.282406
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.281006
GDI2 GDP dissociation inhibitor 2 0.280598
TMEM87A transmembrane protein 87A 0.279773
MAK16 MAK16 homolog (S. cerevisiae) 0.279453
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 0.278645
KRT8 keratin 8, type II 0.278238
HDAC2 histone deacetylase 2 0.276625
EIF5 eukaryotic translation initiation factor 5 0.276426
RAD21 RAD21 homolog (S. pombe) 0.275506
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.274492
NARS asparaginyl-tRNA synthetase 0.274125
CTSZ cathepsin Z 0.272139
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.27047
BZW1 basic leucine zipper and W2 domains 1 0.270319
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.269794
BANF1 barrier to autointegration factor 1 0.269598
KARS lysyl-tRNA synthetase 0.269274
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.268261
SEC24B SEC24 family member B 0.267137
BUD31 BUD31 homolog (S. cerevisiae) 0.266944
PRPF18 pre-mRNA processing factor 18 0.266896
CBX3 chromobox homolog 3 0.266345
GCFC2 GC-rich sequence DNA-binding factor 2 0.264732
TAGLN2 transgelin 2 0.263979
ERCC5 excision repair cross-complementation group 5 0.262493
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.262163
MTMR6 myotubularin related protein 6 0.262125
HAT1 histone acetyltransferase 1 0.261449
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.259985
ESD esterase D 0.258836
RSRC2 arginine/serine-rich coiled-coil 2 0.257927
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.257924
PARP2 poly (ADP-ribose) polymerase 2 0.256413
PRRC2C proline-rich coiled-coil 2C 0.255937
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.255357
KIAA1109 KIAA1109 0.252574
RECQL RecQ helicase-like 0.251258
CETN2 centrin, EF-hand protein, 2 0.248993
PMM1 phosphomannomutase 1 0.248169
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.246891
CUL5 cullin 5 0.246548
MYO7A myosin VIIA 0.245864
SMC3 structural maintenance of chromosomes 3 0.245467
SLC25A42 solute carrier family 25, member 42 0.244803
SEC63 SEC63 homolog (S. cerevisiae) 0.2443
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.244202
PTPRC protein tyrosine phosphatase, receptor type, C 0.243892
ZFAND5 zinc finger, AN1-type domain 5 0.243614
AATK apoptosis-associated tyrosine kinase 0.243154
ERCC6 excision repair cross-complementation group 6 0.243034
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.242343
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.241015
CUL4B cullin 4B 0.239921
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.239818
RBM6 RNA binding motif protein 6 0.239713
OTUD4 OTU deubiquitinase 4 0.239253
CHD1 chromodomain helicase DNA binding protein 1 0.239074
CEP350 centrosomal protein 350kDa 0.238056
CLTC clathrin, heavy chain (Hc) 0.237902
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.237017
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.236162
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.234113
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.233678
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.233563
STAG2 stromal antigen 2 0.232816
GRIP2 glutamate receptor interacting protein 2 0.232182
SRSF5 serine/arginine-rich splicing factor 5 0.230986
TOP2B topoisomerase (DNA) II beta 180kDa 0.230899
PLCB2 phospholipase C, beta 2 0.229659
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.229249
SSTR5 somatostatin receptor 5 0.227724
UBE4B ubiquitination factor E4B 0.227248
EXOSC8 exosome component 8 0.226298
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.225725
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.225652
DNM1L dynamin 1-like 0.224434
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.223531
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.223319
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.221623
RTCA RNA 3'-terminal phosphate cyclase 0.220662
RBBP8 retinoblastoma binding protein 8 0.220403
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.219238
SEC62 SEC62 homolog (S. cerevisiae) 0.219104
USP1 ubiquitin specific peptidase 1 0.219062
TMEM123 transmembrane protein 123 0.218137
PDIA3 protein disulfide isomerase family A, member 3 0.216531
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.21595
FRYL FRY-like 0.215519
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.215063
FLAD1 flavin adenine dinucleotide synthetase 1 0.214971
JUND jun D proto-oncogene 0.213805
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.213245
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.212206
ZNHIT1 zinc finger, HIT-type containing 1 0.211762
GOLGA4 golgin A4 0.211667
ZFC3H1 zinc finger, C3H1-type containing 0.211526
CNBP CCHC-type zinc finger, nucleic acid binding protein 0.211119
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.211044
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.210557
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.209952
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.209855
CFDP1 craniofacial development protein 1 0.208661
CAPRIN1 cell cycle associated protein 1 0.208141
MUT methylmalonyl CoA mutase 0.207733
ALDOB aldolase B, fructose-bisphosphate 0.20721
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.206324
FNBP4 formin binding protein 4 0.206256
RPS27A ribosomal protein S27a 0.205872
IGF2 insulin-like growth factor 2 0.204255
SFPQ splicing factor proline/glutamine-rich 0.204111
CCDC6 coiled-coil domain containing 6 0.203468
ZNF292 zinc finger protein 292 0.203094
SH3YL1 SH3 and SYLF domain containing 1 0.202451
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.202251
RANBP2 RAN binding protein 2 0.200065
ZEB2 zinc finger E-box binding homeobox 2 0.199932
CFL2 cofilin 2 (muscle) 0.199928
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.199788
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.19962
USP8 ubiquitin specific peptidase 8 0.199325
GBAS glioblastoma amplified sequence 0.199051
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 0.198582
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 0.197973
UTRN utrophin 0.197893
FUBP1 far upstream element (FUSE) binding protein 1 0.195766
DUSP3 dual specificity phosphatase 3 0.195588
DENND4A DENN/MADD domain containing 4A 0.195289
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.195123
TPP2 tripeptidyl peptidase II 0.194888
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.194705
NOL7 nucleolar protein 7, 27kDa 0.194676
SMC5 structural maintenance of chromosomes 5 0.193948
TUBA1A tubulin, alpha 1a 0.191915
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.190641
UBA2 ubiquitin-like modifier activating enzyme 2 0.190396
ZNF148 zinc finger protein 148 0.19037
GSK3A glycogen synthase kinase 3 alpha 0.190228
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.189772
METAP1 methionyl aminopeptidase 1 0.189653
ELF1 E74-like factor 1 (ets domain transcription factor) 0.189321
PDHX pyruvate dehydrogenase complex, component X 0.189019
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 0.188847
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.18881
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 0.188372
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.188193
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.187863
SECISBP2L SECIS binding protein 2-like 0.187519
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 0.187492
MBD4 methyl-CpG binding domain protein 4 0.187453
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 0.187068
ZNF146 zinc finger protein 146 0.186836
SCFD1 sec1 family domain containing 1 0.186603
TLK1 tousled-like kinase 1 0.186008
PIBF1 progesterone immunomodulatory binding factor 1 0.185726
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.185029
PAPOLA poly(A) polymerase alpha 0.184793
TMF1 TATA element modulatory factor 1 0.184712
ERI3 ERI1 exoribonuclease family member 3 0.18419
OSBPL8 oxysterol binding protein-like 8 0.183909
C1D C1D nuclear receptor corepressor 0.183877
EID1 EP300 interacting inhibitor of differentiation 1 0.183751
WTAP Wilms tumor 1 associated protein 0.183628
EIF3H eukaryotic translation initiation factor 3, subunit H 0.183604
CD81 CD81 molecule 0.183234
TRIM13 tripartite motif containing 13 0.182885
TRA2B transformer 2 beta homolog (Drosophila) 0.182875
CUL2 cullin 2 0.182795
COPS6 COP9 signalosome subunit 6 0.182581
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 0.182302
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.181848
VRK1 vaccinia related kinase 1 0.181842
TWF1 twinfilin actin binding protein 1 0.181741
TOP1P2 topoisomerase (DNA) I pseudogene 2 0.181594
GAA glucosidase, alpha; acid 0.181295
AMPD2 adenosine monophosphate deaminase 2 0.181105
MED6 mediator complex subunit 6 0.180571
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.180344
URI1 URI1, prefoldin-like chaperone 0.180303
NCL nucleolin 0.180125
ING3 inhibitor of growth family, member 3 0.179884
FNTA farnesyltransferase, CAAX box, alpha 0.179305
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.17909
TRAPPC8 trafficking protein particle complex 8 0.178847
AQP2 aquaporin 2 (collecting duct) 0.178589
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.177715
CLDND1 claudin domain containing 1 0.177661
FLNA filamin A, alpha 0.177645
EPS15 epidermal growth factor receptor pathway substrate 15 0.177406
TARS threonyl-tRNA synthetase 0.177381
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.177224
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.176957
C6ORF62 chromosome 6 open reading frame 62 0.17641
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.175641
PHF3 PHD finger protein 3 0.175396
ETF1 eukaryotic translation termination factor 1 0.175316
BPTF bromodomain PHD finger transcription factor 0.174993
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 0.174816
CFD complement factor D (adipsin) 0.174368
IDI1 isopentenyl-diphosphate delta isomerase 1 0.173883
BAX BCL2-associated X protein 0.172774
EMP3 epithelial membrane protein 3 0.172586
RNMT RNA (guanine-7-) methyltransferase 0.172424
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.172216
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.172124

decreased expression

Symbol Name Standardized Value
CLPS colipase, pancreatic -6.48777
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -5.05056
DGCR6L DiGeorge syndrome critical region gene 6-like -1.86385
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.481661
HDGF hepatoma-derived growth factor -0.426674
ARID1A AT rich interactive domain 1A (SWI-like) -0.413309
DAPK2 death-associated protein kinase 2 -0.391132
WHSC1 Wolf-Hirschhorn syndrome candidate 1 -0.378971
CAMP cathelicidin antimicrobial peptide -0.35003
RNF115 ring finger protein 115 -0.348636
CAPZB capping protein (actin filament) muscle Z-line, beta -0.330539
ANXA11 annexin A11 -0.325879
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -0.30779
XPO6 exportin 6 -0.302606
WDR1 WD repeat domain 1 -0.297955
TUBG1 tubulin, gamma 1 -0.291384
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) -0.287802
CRYBA4 crystallin, beta A4 -0.286128
LOR loricrin -0.279762
NOTCH3 notch 3 -0.277329
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.276866
ANK1 ankyrin 1, erythrocytic -0.274556
CREBBP CREB binding protein -0.273301
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -0.265291
RCOR1 REST corepressor 1 -0.262884
PRKCE protein kinase C, epsilon -0.261284
LBP lipopolysaccharide binding protein -0.25989
NFIA nuclear factor I/A -0.251144
MVK mevalonate kinase -0.250514
BAG1 BCL2-associated athanogene -0.248739
VAMP3 vesicle-associated membrane protein 3 -0.248709
CS citrate synthase -0.247945
ZDHHC3 zinc finger, DHHC-type containing 3 -0.243171
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -0.239943
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -0.236781
PCBP2 poly(rC) binding protein 2 -0.234943
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -0.234223
ORC1 origin recognition complex, subunit 1 -0.232255
SNX27 sorting nexin family member 27 -0.23082
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.230594
TMED9 transmembrane emp24 protein transport domain containing 9 -0.228347
KDM3B lysine (K)-specific demethylase 3B -0.227645
SRSF9 serine/arginine-rich splicing factor 9 -0.225893
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 -0.22448
HIPK1 homeodomain interacting protein kinase 1 -0.22244
WIPF2 WAS/WASL interacting protein family, member 2 -0.222036
NUP188 nucleoporin 188kDa -0.221875
SEC61G Sec61 gamma subunit -0.219559
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -0.219497
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -0.2187
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.21804
EIF1B eukaryotic translation initiation factor 1B -0.217284
RPIA ribose 5-phosphate isomerase A -0.216819
DLG3 discs, large homolog 3 (Drosophila) -0.213433
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.211584
GRM4 glutamate receptor, metabotropic 4 -0.211229
H2AFZ H2A histone family, member Z -0.210699
CDYL chromodomain protein, Y-like -0.210102
TRIP13 thyroid hormone receptor interactor 13 -0.209764
SSR4 signal sequence receptor, delta -0.208256
NFYB nuclear transcription factor Y, beta -0.208211
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.204954
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.204491
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -0.204321
ZNF384 zinc finger protein 384 -0.204159
TAGLN transgelin -0.203397
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.203135
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.202303
IGKC immunoglobulin kappa constant -0.201539
FBXO46 F-box protein 46 -0.201336
NECAB3 N-terminal EF-hand calcium binding protein 3 -0.201058
TCF3 transcription factor 3 -0.200427
GGT5 gamma-glutamyltransferase 5 -0.199293
TCOF1 Treacher Collins-Franceschetti syndrome 1 -0.198546
RAE1 ribonucleic acid export 1 -0.198263
SIK3 SIK family kinase 3 -0.198229
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -0.197763
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.197754
TIMELESS timeless circadian clock -0.197169
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.196706
GPR17 G protein-coupled receptor 17 -0.19666
ARF5 ADP-ribosylation factor 5 -0.195976
DPF2 D4, zinc and double PHD fingers family 2 -0.195666
ACLY ATP citrate lyase -0.195271
BGN biglycan -0.191819
PHF2 PHD finger protein 2 -0.19113
COL6A2 collagen, type VI, alpha 2 -0.188893
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.188608
RABAC1 Rab acceptor 1 (prenylated) -0.188282
IST1 increased sodium tolerance 1 homolog (yeast) -0.188115
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -0.185044
NCAPD2 non-SMC condensin I complex, subunit D2 -0.184496
MPC2 mitochondrial pyruvate carrier 2 -0.184486
RAD54L RAD54-like (S. cerevisiae) -0.183814
RPL15 ribosomal protein L15 -0.183596
FOXJ2 forkhead box J2 -0.182547
HIRA histone cell cycle regulator -0.182116
YIPF6 Yip1 domain family, member 6 -0.181831
CABIN1 calcineurin binding protein 1 -0.17843
NOP2 NOP2 nucleolar protein -0.177818
SETD1B SET domain containing 1B -0.176607
HPN hepsin -0.17509
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.174802
LOC391322 D-dopachrome tautomerase-like -0.174662
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -0.174652
KRT2 keratin 2, type II -0.172974
TRRAP transformation/transcription domain-associated protein -0.171147
SGSM2 small G protein signaling modulator 2 -0.17078
TRIM66 tripartite motif containing 66 -0.169973
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -0.169711
ILK integrin-linked kinase -0.169393
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.168616
DDB1 damage-specific DNA binding protein 1, 127kDa -0.168113
LASP1 LIM and SH3 protein 1 -0.167191
TRAPPC3 trafficking protein particle complex 3 -0.16698
FBXO7 F-box protein 7 -0.16539
LUZP1 leucine zipper protein 1 -0.164881
CRAT carnitine O-acetyltransferase -0.164477
POGZ pogo transposable element with ZNF domain -0.164401
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.164332
CHIT1 chitinase 1 (chitotriosidase) -0.163185
TLN2 talin 2 -0.16313
CCKAR cholecystokinin A receptor -0.162415
SEC61B Sec61 beta subunit -0.162005
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.160469
CRCP CGRP receptor component -0.160345
MTMR3 myotubularin related protein 3 -0.159725
OPRL1 opiate receptor-like 1 -0.158926
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -0.158703
MYH9 myosin, heavy chain 9, non-muscle -0.158533
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.158204
ALAS1 5'-aminolevulinate synthase 1 -0.157684
H2AFV H2A histone family, member V -0.157534
ARCN1 archain 1 -0.156648
RPA3 replication protein A3, 14kDa -0.156381
DCTN2 dynactin 2 (p50) -0.156334
SLPI secretory leukocyte peptidase inhibitor -0.155852
MTMR1 myotubularin related protein 1 -0.155604
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.155223
DHCR7 7-dehydrocholesterol reductase -0.15463
MCM2 minichromosome maintenance complex component 2 -0.154355
P3H3 prolyl 3-hydroxylase 3 -0.153662
SNRPE small nuclear ribonucleoprotein polypeptide E -0.153534
JRK Jrk homolog (mouse) -0.152717
MDC1 mediator of DNA-damage checkpoint 1 -0.152636
QDPR quinoid dihydropteridine reductase -0.152288
CPT1A carnitine palmitoyltransferase 1A (liver) -0.151902
HMGB1 high mobility group box 1 -0.151818
STK24 serine/threonine kinase 24 -0.150989
RALB v-ral simian leukemia viral oncogene homolog B -0.150059
LYPD3 LY6/PLAUR domain containing 3 -0.14946
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.148897
ADCY6 adenylate cyclase 6 -0.148587
STX3 syntaxin 3 -0.148544
MFN2 mitofusin 2 -0.148458
CHD8 chromodomain helicase DNA binding protein 8 -0.148081
SRSF2 serine/arginine-rich splicing factor 2 -0.147224
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.146802
SREBF1 sterol regulatory element binding transcription factor 1 -0.146712
TXNL4A thioredoxin-like 4A -0.146149
KRT5 keratin 5, type II -0.145884
TMEM11 transmembrane protein 11 -0.14534
EHD1 EH-domain containing 1 -0.145316
ANXA7 annexin A7 -0.144976
VCL vinculin -0.144559
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.144357
ECE2 endothelin converting enzyme 2 -0.143975
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 -0.143661
UVRAG UV radiation resistance associated -0.143405
ZWINT ZW10 interacting kinetochore protein -0.142202
TMED2 transmembrane emp24 domain trafficking protein 2 -0.142187
CTTN cortactin -0.141557
CLASP1 cytoplasmic linker associated protein 1 -0.141396
FAM134C family with sequence similarity 134, member C -0.141057
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.14095
SUN1 Sad1 and UNC84 domain containing 1 -0.140912
WDR37 WD repeat domain 37 -0.140601
GOLGA3 golgin A3 -0.140487
ARF4 ADP-ribosylation factor 4 -0.140481
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -0.140437
OCRL oculocerebrorenal syndrome of Lowe -0.140234
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -0.140002
SERINC3 serine incorporator 3 -0.138904
IGFBP5 insulin-like growth factor binding protein 5 -0.138268
RSU1 Ras suppressor protein 1 -0.13777
GANAB glucosidase, alpha; neutral AB -0.137448
PGM1 phosphoglucomutase 1 -0.137201
HAX1 HCLS1 associated protein X-1 -0.137126
SART3 squamous cell carcinoma antigen recognized by T cells 3 -0.13662
HMGN2 high mobility group nucleosomal binding domain 2 -0.136294
UBQLN2 ubiquilin 2 -0.136195
GCA grancalcin, EF-hand calcium binding protein -0.136081
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.135657
SF3A1 splicing factor 3a, subunit 1, 120kDa -0.135585
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.135073
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -0.134995
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -0.134977
SCRIB scribbled planar cell polarity protein -0.134355
SRRM1 serine/arginine repetitive matrix 1 -0.134111
CSNK1D casein kinase 1, delta -0.13386
BAHD1 bromo adjacent homology domain containing 1 -0.133732
LPO lactoperoxidase -0.133218
OAZ1 ornithine decarboxylase antizyme 1 -0.132427
LOC728093 putative POM121-like protein 1-like -0.13198
RPP30 ribonuclease P/MRP 30kDa subunit -0.131967
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.131401
CASC3 cancer susceptibility candidate 3 -0.131171
TUBB2B tubulin, beta 2B class IIb -0.130069
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.130043
MXRA8 matrix-remodelling associated 8 -0.130024
TK1 thymidine kinase 1, soluble -0.129948
KRT10 keratin 10, type I -0.129536
MKRN1 makorin ring finger protein 1 -0.129351
RNF44 ring finger protein 44 -0.129291
IFITM2 interferon induced transmembrane protein 2 -0.129218
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.128945
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.128905
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.12884
PRDX4 peroxiredoxin 4 -0.12861
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.128296
TSPO2 translocator protein 2 -0.127926
GPATCH8 G patch domain containing 8 -0.127542
CTF1 cardiotrophin 1 -0.126986
UBE2I ubiquitin-conjugating enzyme E2I -0.126833
CRHR1 corticotropin releasing hormone receptor 1 -0.126176
CD63 CD63 molecule -0.125591
C1QB complement component 1, q subcomponent, B chain -0.124921
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.124762
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.124744
KLC1 kinesin light chain 1 -0.123965
SLC25A44 solute carrier family 25, member 44 -0.123477
PLIN1 perilipin 1 -0.123271
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.123041
UBE3B ubiquitin protein ligase E3B -0.12304
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -0.122515
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.121794
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.121505
CENPA centromere protein A -0.121057
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.120443
TACSTD2 tumor-associated calcium signal transducer 2 -0.12026
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.120083
PPP1R3D protein phosphatase 1, regulatory subunit 3D -0.119437
TALDO1 transaldolase 1 -0.119183
SH2B1 SH2B adaptor protein 1 -0.119147
DUT deoxyuridine triphosphatase -0.118497
COL1A2 collagen, type I, alpha 2 -0.118292
RNF114 ring finger protein 114 -0.117946
MFAP2 microfibrillar-associated protein 2 -0.117321
RAB13 RAB13, member RAS oncogene family -0.117096
TXN thioredoxin -0.117002
LOC646652 integral membrane glycoprotein-like -0.116762
RANBP3 RAN binding protein 3 -0.116652
HIST1H4C histone cluster 1, H4c -0.116545
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -0.116498
SMAD9 SMAD family member 9 -0.116085
FOSL1 FOS-like antigen 1 -0.115652
BAAT bile acid CoA:amino acid N-acyltransferase -0.115492
SIN3B SIN3 transcription regulator family member B -0.114865
CHMP2A charged multivesicular body protein 2A -0.114068
TCL1B T-cell leukemia/lymphoma 1B -0.113789
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -0.113652
C1ORF216 chromosome 1 open reading frame 216 -0.113375
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -0.11332
GRAMD4 GRAM domain containing 4 -0.113289
DAP death-associated protein -0.11324
ARF3 ADP-ribosylation factor 3 -0.112857
SCN4A sodium channel, voltage gated, type IV alpha subunit -0.112612
RANBP1 RAN binding protein 1 -0.112611
HTRA2 HtrA serine peptidase 2 -0.11258
MME membrane metallo-endopeptidase -0.11227
ODF1 outer dense fiber of sperm tails 1 -0.11224
POM121 POM121 transmembrane nucleoporin -0.111827
TYMS thymidylate synthetase -0.111602
IRF2 interferon regulatory factor 2 -0.111479
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.111415
APC2 adenomatosis polyposis coli 2 -0.11097
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 -0.11068
FPR2 formyl peptide receptor 2 -0.110337
CD8A CD8a molecule -0.109976
M6PR mannose-6-phosphate receptor (cation dependent) -0.10961
MICB MHC class I polypeptide-related sequence B -0.109562
ARSE arylsulfatase E (chondrodysplasia punctata 1) -0.109414
FOXO3 forkhead box O3 -0.109169
CRH corticotropin releasing hormone -0.109069
F8 coagulation factor VIII, procoagulant component -0.108913
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 -0.108795
LDHA lactate dehydrogenase A -0.108755
SRCAP Snf2-related CREBBP activator protein -0.108711
CELA2A chymotrypsin-like elastase family, member 2A -0.108311
XPO7 exportin 7 -0.108027
FAM8A1 family with sequence similarity 8, member A1 -0.107892
ZNF134 zinc finger protein 134 -0.107853
SIAH2 siah E3 ubiquitin protein ligase 2 -0.107792
HIST1H2BI histone cluster 1, H2bi -0.107767
GHRH growth hormone releasing hormone -0.107661
NUP62 nucleoporin 62kDa -0.107367
R3HDM2 R3H domain containing 2 -0.107064
SCARB2 scavenger receptor class B, member 2 -0.106811
XBP1 X-box binding protein 1 -0.106713
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -0.106651