AH-6809-7075 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the AH-6809-7075 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD6 abhydrolase domain containing 6
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BAG4 BCL2-associated athanogene 4
BIN1 bridging integrator 1
BTBD18 BTB (POZ) domain containing 18
C10ORF88 chromosome 10 open reading frame 88
C17ORF70 chromosome 17 open reading frame 70
CABIN1 calcineurin binding protein 1
CALCOCO1 calcium binding and coiled-coil domain 1
CALD1 caldesmon 1
CAPN2 calpain 2, (m/II) large subunit
CCDC6 coiled-coil domain containing 6
CCNE1 cyclin E1
CCNJL cyclin J-like
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPT centromere protein T
CEP112 centrosomal protein 112kDa
CLCN3 chloride channel, voltage-sensitive 3
COL5A1 collagen, type V, alpha 1
COPA coatomer protein complex, subunit alpha
CTSZ cathepsin Z
CUX1 cut-like homeobox 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DHODH dihydroorotate dehydrogenase (quinone)
ELF4 E74-like factor 4 (ets domain transcription factor)
EN1 engrailed homeobox 1
FAM174B family with sequence similarity 174, member B
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPR3 G protein-coupled receptor 3
KCTD13 potassium channel tetramerization domain containing 13
KDM6B lysine (K)-specific demethylase 6B
KIAA0930 KIAA0930
KIF13A kinesin family member 13A
KLF6 Kruppel-like factor 6
KRT4 keratin 4, type II
LOC157562 uncharacterized LOC157562
MAGEA6 melanoma antigen family A6
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MCM3AP minichromosome maintenance complex component 3 associated protein
MED25 mediator complex subunit 25
METTL3 methyltransferase like 3
MFSD6 major facilitator superfamily domain containing 6
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNX1 motor neuron and pancreas homeobox 1
MXRA8 matrix-remodelling associated 8
NARFL nuclear prelamin A recognition factor-like
NDRG4 NDRG family member 4
NME5 NME/NM23 family member 5
NPDC1 neural proliferation, differentiation and control, 1
NUP205 nucleoporin 205kDa
ORAI3 ORAI calcium release-activated calcium modulator 3
PACS2 phosphofurin acidic cluster sorting protein 2
PBX1 pre-B-cell leukemia homeobox 1
PBX2 pre-B-cell leukemia homeobox 2
PDAP1 PDGFA associated protein 1
PEX1 peroxisomal biogenesis factor 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRMT7 protein arginine methyltransferase 7
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PVR poliovirus receptor
QKI QKI, KH domain containing, RNA binding
RAB2A RAB2A, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RBM12 RNA binding motif protein 12
SIDT2 SID1 transmembrane family, member 2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOCS6 suppressor of cytokine signaling 6
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STX3 syntaxin 3
SUGP1 SURP and G patch domain containing 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCF4 transcription factor 4
TCTN1 tectonic family member 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TPMT thiopurine S-methyltransferase
TRAK1 trafficking protein, kinesin binding 1
TRIM25 tripartite motif containing 25
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UNC119 unc-119 homolog (C. elegans)
URI1 URI1, prefoldin-like chaperone
URM1 ubiquitin related modifier 1
USP6NL USP6 N-terminal like
ZC3H7B zinc finger CCCH-type containing 7B
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK3 alpha-kinase 3
ANXA10 annexin A10
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BAK1 BCL2-antagonist/killer 1
BBS10 Bardet-Biedl syndrome 10
BCL9 B-cell CLL/lymphoma 9
C17ORF53 chromosome 17 open reading frame 53
C17ORF80 chromosome 17 open reading frame 80
CAPN5 calpain 5
CBR4 carbonyl reductase 4
CCNJ cyclin J
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP97 centrosomal protein 97kDa
CHM choroideremia (Rab escort protein 1)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNPY3 canopy FGF signaling regulator 3
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
ECM1 extracellular matrix protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FAM188A family with sequence similarity 188, member A
FCHSD2 FCH and double SH3 domains 2
FPGT fucose-1-phosphate guanylyltransferase
GPALPP1 GPALPP motifs containing 1
GPR1 G protein-coupled receptor 1
GRAMD4 GRAM domain containing 4
HIST1H2AG histone cluster 1, H2ag
HIST1H2BI histone cluster 1, H2bi
HOOK1 hook microtubule-tethering protein 1
HS1BP3 HCLS1 binding protein 3
IFI6 interferon, alpha-inducible protein 6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
LIG4 ligase IV, DNA, ATP-dependent
LNPEP leucyl/cystinyl aminopeptidase
LPAR6 lysophosphatidic acid receptor 6
MAVS mitochondrial antiviral signaling protein
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM9 minichromosome maintenance complex component 9
METRN meteorin, glial cell differentiation regulator
MNS1 meiosis-specific nuclear structural 1
NFS1 NFS1 cysteine desulfurase
NOTCH1 notch 1
NRSN2 neurensin 2
NXPH4 neurexophilin 4
ONECUT2 one cut homeobox 2
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PARP3 poly (ADP-ribose) polymerase family, member 3
PDGFRL platelet-derived growth factor receptor-like
PER3 period circadian clock 3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
POU5F1B POU class 5 homeobox 1B
PRSS22 protease, serine, 22
RNF25 ring finger protein 25
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RSRC1 arginine/serine-rich coiled-coil 1
RWDD2A RWD domain containing 2A
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SERTAD3 SERTA domain containing 3
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNHG3 small nucleolar RNA host gene 3
SSNA1 Sjogren syndrome nuclear autoantigen 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK25 serine/threonine kinase 25
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAOK1 TAO kinase 1
TCTA T-cell leukemia translocation altered
TEP1 telomerase-associated protein 1
TMC7 transmembrane channel-like 7
TMCC2 transmembrane and coiled-coil domain family 2
TMOD3 tropomodulin 3 (ubiquitous)
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TTF2 transcription termination factor, RNA polymerase II
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ULBP2 UL16 binding protein 2
ZBTB22 zinc finger and BTB domain containing 22
ZBTB3 zinc finger and BTB domain containing 3
ZNF574 zinc finger protein 574
ZNF696 zinc finger protein 696