AH-23848-6890 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the AH-23848-6890 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADAM22 ADAM metallopeptidase domain 22
AKAP10 A kinase (PRKA) anchor protein 10
AKT2 v-akt murine thymoma viral oncogene homolog 2
APOC1 apolipoprotein C-I
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASPH aspartate beta-hydroxylase
ATXN2L ataxin 2-like
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BIRC7 baculoviral IAP repeat containing 7
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF80 chromosome 11 open reading frame 80
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
CAPN2 calpain 2, (m/II) large subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CFHR4 complement factor H-related 4
CIDEC cell death-inducing DFFA-like effector c
CLU clusterin
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COPA coatomer protein complex, subunit alpha
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DST dystonin
ELOVL5 ELOVL fatty acid elongase 5
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ESR1 estrogen receptor 1
EXTL3 exostosin-like glycosyltransferase 3
FBXO31 F-box protein 31
FGFR1 fibroblast growth factor receptor 1
FH fumarate hydratase
FLOT2 flotillin 2
FOSL2 FOS-like antigen 2
GLB1L galactosidase, beta 1-like
HABP4 hyaluronan binding protein 4
HFE hemochromatosis
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2AJ histone cluster 1, H2aj
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPS1 Hermansky-Pudlak syndrome 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF8 interferon regulatory factor 8
ITCH itchy E3 ubiquitin protein ligase
KAZN kazrin, periplakin interacting protein
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF13A kinesin family member 13A
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAP1B microtubule-associated protein 1B
MARK2 MAP/microtubule affinity-regulating kinase 2
MATK megakaryocyte-associated tyrosine kinase
MPPE1 metallophosphoesterase 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NOD2 nucleotide-binding oligomerization domain containing 2
NRF1 nuclear respiratory factor 1
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PALM paralemmin
PDE4A phosphodiesterase 4A, cAMP-specific
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCG1 phospholipase C, gamma 1
POLL polymerase (DNA directed), lambda
PPT2 palmitoyl-protein thioesterase 2
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PSD4 pleckstrin and Sec7 domain containing 4
QPCTL glutaminyl-peptide cyclotransferase-like
RAB35 RAB35, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RNF19B ring finger protein 19B
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC48A1 solute carrier family 48 (heme transporter), member 1
SOGA1 suppressor of glucose, autophagy associated 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPAST spastin
SRPR signal recognition particle receptor (docking protein)
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
STRN striatin, calmodulin binding protein
SUGP1 SURP and G patch domain containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCTN2 tectonic family member 2
TMC5 transmembrane channel-like 5
TMCO3 transmembrane and coiled-coil domains 3
TMEM259 transmembrane protein 259
TPSG1 tryptase gamma 1
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
WDR48 WD repeat domain 48
WDR61 WD repeat domain 61
ZNF444 zinc finger protein 444
ZNF701 zinc finger protein 701
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADAP2 ArfGAP with dual PH domains 2
APOD apolipoprotein D
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BBC3 BCL2 binding component 3
BBS7 Bardet-Biedl syndrome 7
C8ORF44 chromosome 8 open reading frame 44
CCDC7 coiled-coil domain containing 7
CFD complement factor D (adipsin)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CORO1A coronin, actin binding protein, 1A
CRLF1 cytokine receptor-like factor 1
CRYBG3 beta-gamma crystallin domain containing 3
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DIXDC1 DIX domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK1 dedicator of cytokinesis 1
DTX2 deltex 2, E3 ubiquitin ligase
DZANK1 double zinc ribbon and ankyrin repeat domains 1
FAM155B family with sequence similarity 155, member B
FKBP10 FK506 binding protein 10, 65 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FLT4 fms-related tyrosine kinase 4
FMO4 flavin containing monooxygenase 4
FZD4 frizzled class receptor 4
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
H1F0 H1 histone family, member 0
HDAC4 histone deacetylase 4
HIST1H2AL histone cluster 1, H2al
HIST1H4D histone cluster 1, H4d
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA4 homeobox A4
HSPA1L heat shock 70kDa protein 1-like
IL15RA interleukin 15 receptor, alpha
INPP5J inositol polyphosphate-5-phosphatase J
KDM8 lysine (K)-specific demethylase 8
KIAA0125 KIAA0125
KIFAP3 kinesin-associated protein 3
KLHL25 kelch-like family member 25
KRI1 KRI1 homolog (S. cerevisiae)
LMBR1L limb development membrane protein 1-like
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP9 microtubule-associated protein 9
MIR22HG MIR22 host gene
NAV2 neuron navigator 2
NECAP2 NECAP endocytosis associated 2
NRSN2 neurensin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGFRL1 opioid growth factor receptor-like 1
OLFML2A olfactomedin-like 2A
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PACS1 phosphofurin acidic cluster sorting protein 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G10 phospholipase A2, group X
PMCH pro-melanin-concentrating hormone
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POM121 POM121 transmembrane nucleoporin
PRSS16 protease, serine, 16 (thymus)
QSER1 glutamine and serine rich 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
REPS2 RALBP1 associated Eps domain containing 2
RGS19 regulator of G-protein signaling 19
RNF146 ring finger protein 146
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP7 ribosomal protein L23a pseudogene 7
SCN1B sodium channel, voltage gated, type I beta subunit
SCPEP1 serine carboxypeptidase 1
SECTM1 secreted and transmembrane 1
SIK1 salt-inducible kinase 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNX16 sorting nexin 16
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TICAM1 toll-like receptor adaptor molecule 1
TMEM104 transmembrane protein 104
TMEM132A transmembrane protein 132A
TRAIP TRAF interacting protein
TRIM52 tripartite motif containing 52
TUBG2 tubulin, gamma 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USB1 U6 snRNA biogenesis 1
WDR19 WD repeat domain 19
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF33B zinc finger protein 33B
ZNF551 zinc finger protein 551
ZNF573 zinc finger protein 573
ZNF696 zinc finger protein 696