ACVR1C Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description activin A receptor, type IC|ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 130399)
External Link http://www.ncbi.nlm.nih.gov/gene/130399
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Genes

26 interacting proteins for ACVR1C from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACVR1B activin A receptor, type IB
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
BAMBI BMP and activin membrane-bound inhibitor
CER1 cerberus 1, DAN family BMP antagonist
CFC1 cripto, FRL-1, cryptic family 1
FKBP1A FK506 binding protein 1A, 12kDa
GDF11 growth differentiation factor 11
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
INHBA inhibin, beta A
INHBB inhibin, beta B
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K7CL MAP3K7 C-terminal like
NODAL nodal growth differentiation factor
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
RRAS related RAS viral (r-ras) oncogene homolog
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD9 SMAD family member 9
TDGF1 teratocarcinoma-derived growth factor 1
TGFBR1 transforming growth factor, beta receptor 1