A-427 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Similar Terms
Downloads & Tools


135 genes mutated in the A-427 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACO1 aconitase 1, soluble
ADGRL3 adhesion G protein-coupled receptor L3
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD52 ankyrin repeat domain 52
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AQR aquarius intron-binding spliceosomal factor
ARHGAP1 Rho GTPase activating protein 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ASCC2 activating signal cointegrator 1 complex subunit 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASXL1 additional sex combs like transcriptional regulator 1
ATRNL1 attractin-like 1
BCOR BCL6 corepressor
BECN1 beclin 1, autophagy related
BTBD7 BTB (POZ) domain containing 7
C11ORF31 chromosome 11 open reading frame 31
C19ORF57 chromosome 19 open reading frame 57
C22ORF23 chromosome 22 open reading frame 23
CALD1 caldesmon 1
CARS cysteinyl-tRNA synthetase
CDC23 cell division cycle 23
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CMTR1 cap methyltransferase 1
CNOT1 CCR4-NOT transcription complex, subunit 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CUBN cubilin (intrinsic factor-cobalamin receptor)
DIAPH1 diaphanous-related formin 1
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DLL3 delta-like 3 (Drosophila)
DST dystonin
E2F7 E2F transcription factor 7
EIF3H eukaryotic translation initiation factor 3, subunit H
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
F8 coagulation factor VIII, procoagulant component
FAM160B1 family with sequence similarity 160, member B1
FAM49B family with sequence similarity 49, member B
FARSB phenylalanyl-tRNA synthetase, beta subunit
FBN3 fibrillin 3
FPGT fucose-1-phosphate guanylyltransferase
FZD6 frizzled class receptor 6
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IFT20 intraflagellar transport 20
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INSR insulin receptor
IREB2 iron-responsive element binding protein 2
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KDM4C lysine (K)-specific demethylase 4C
KIF14 kinesin family member 14
KLF13 Kruppel-like factor 13
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LIG1 ligase I, DNA, ATP-dependent
LMNB2 lamin B2
LPIN3 lipin 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAML1 mastermind-like 1 (Drosophila)
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
MAT1A methionine adenosyltransferase I, alpha
MCM2 minichromosome maintenance complex component 2
MCPH1 microcephalin 1
MMS22L MMS22-like, DNA repair protein
MRPS30 mitochondrial ribosomal protein S30
MSH2 mutS homolog 2
MTMR8 myotubularin related protein 8
MYO5A myosin VA (heavy chain 12, myoxin)
NAP1L2 nucleosome assembly protein 1-like 2
NDN necdin, melanoma antigen (MAGE) family member
NEK4 NIMA-related kinase 4
NPHP4 nephronophthisis 4
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NUPL1 nucleoporin like 1
OR2W3 olfactory receptor, family 2, subfamily W, member 3
PACS2 phosphofurin acidic cluster sorting protein 2
PGM1 phosphoglucomutase 1
PHKB phosphorylase kinase, beta
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PITX1 paired-like homeodomain 1
PLCD1 phospholipase C, delta 1
PNKD paroxysmal nonkinesigenic dyskinesia
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRR3 proline rich 3
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RABL3 RAB, member of RAS oncogene family-like 3
RBM10 RNA binding motif protein 10
RBM11 RNA binding motif protein 11
RBM26 RNA binding motif protein 26
RIN3 Ras and Rab interactor 3
RING1 ring finger protein 1
RNF10 ring finger protein 10
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPUSD1 RNA pseudouridylate synthase domain containing 1
RTTN rotatin
SBNO2 strawberry notch homolog 2 (Drosophila)
SEC31A SEC31 homolog A (S. cerevisiae)
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHOX2 short stature homeobox 2
SLC38A4 solute carrier family 38, member 4
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMO smoothened, frizzled class receptor
SNIP1 Smad nuclear interacting protein 1
SRRT serrate, RNA effector molecule
STARD8 StAR-related lipid transfer (START) domain containing 8
SYVN1 synovial apoptosis inhibitor 1, synoviolin
THSD7A thrombospondin, type I, domain containing 7A
TMC6 transmembrane channel-like 6
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast)
TPP1 tripeptidyl peptidase I
TRIOBP TRIO and F-actin binding protein
TSC2 tuberous sclerosis 2
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE3D ubiquitin protein ligase E3D
ULK1 unc-51 like autophagy activating kinase 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP8 ubiquitin specific peptidase 8
VASH1 vasohibin 1
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
YTHDC2 YTH domain containing 2
ZBTB47 zinc finger and BTB domain containing 47
ZC3H12B zinc finger CCCH-type containing 12B
ZFHX4 zinc finger homeobox 4
ZFP28 ZFP28 zinc finger protein
ZNF22 zinc finger protein 22
ZNF260 zinc finger protein 260
ZNF318 zinc finger protein 318
ZSCAN18 zinc finger and SCAN domain containing 18