928 MEL Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from skin (Klijn et al., Nat. Biotechnol., 2015)
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194 genes mutated in the 928 MEL cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACP5 acid phosphatase 5, tartrate resistant
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADARB1 adenosine deaminase, RNA-specific, B1
AGFG2 ArfGAP with FG repeats 2
AKAP13 A kinase (PRKA) anchor protein 13
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
AP5B1 adaptor-related protein complex 5, beta 1 subunit
AQR aquarius intron-binding spliceosomal factor
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ASCC3 activating signal cointegrator 1 complex subunit 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD2 ATPase family, AAA domain containing 2
ATG4B autophagy related 4B, cysteine peptidase
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
B3GALTL beta 1,3-galactosyltransferase-like
BCL9L B-cell CLL/lymphoma 9-like
BCR breakpoint cluster region
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRICD5 BRICHOS domain containing 5
BUB3 BUB3 mitotic checkpoint protein
C11ORF84 chromosome 11 open reading frame 84
C17ORF53 chromosome 17 open reading frame 53
C1ORF74 chromosome 1 open reading frame 74
C2CD5 C2 calcium-dependent domain containing 5
C6ORF136 chromosome 6 open reading frame 136
CCAR1 cell division cycle and apoptosis regulator 1
CCM2 cerebral cavernous malformation 2
CDK11B cyclin-dependent kinase 11B
CDK12 cyclin-dependent kinase 12
CENPE centromere protein E, 312kDa
CEP250 centrosomal protein 250kDa
CEP350 centrosomal protein 350kDa
CHD6 chromodomain helicase DNA binding protein 6
CHML choroideremia-like (Rab escort protein 2)
CHSY3 chondroitin sulfate synthase 3
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSPP1 centrosome and spindle pole associated protein 1
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DCAF8 DDB1 and CUL4 associated factor 8
DCP1B decapping mRNA 1B
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DNAAF3 dynein, axonemal, assembly factor 3
DPH7 diphthamide biosynthesis 7
DSG2 desmoglein 2
ECH1 enoyl CoA hydratase 1, peroxisomal
EEA1 early endosome antigen 1
EFHC1 EF-hand domain (C-terminal) containing 1
EP300 E1A binding protein p300
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETV6 ets variant 6
EXOC1 exocyst complex component 1
FAM175B family with sequence similarity 175, member B
FAM69C family with sequence similarity 69, member C
FASN fatty acid synthase
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FER fer (fps/fes related) tyrosine kinase
FOXM1 forkhead box M1
GAK cyclin G associated kinase
GAS2L1 growth arrest-specific 2 like 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GTSE1 G-2 and S-phase expressed 1
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HTT huntingtin
HYOU1 hypoxia up-regulated 1
IDS iduronate 2-sulfatase
IP6K2 inositol hexakisphosphate kinase 2
IQGAP1 IQ motif containing GTPase activating protein 1
ISM1 isthmin 1, angiogenesis inhibitor
ITSN1 intersectin 1 (SH3 domain protein)
KANSL1 KAT8 regulatory NSL complex subunit 1
KAT6B K(lysine) acetyltransferase 6B
KDM5A lysine (K)-specific demethylase 5A
KHNYN KH and NYN domain containing
KIF3B kinesin family member 3B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2D lysine (K)-specific methyltransferase 2D
KREMEN1 kringle containing transmembrane protein 1
LENG8 leukocyte receptor cluster (LRC) member 8
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMTK2 lemur tyrosine kinase 2
LPAR3 lysophosphatidic acid receptor 3
LRWD1 leucine-rich repeats and WD repeat domain containing 1
LSM12 LSM12 homolog (S. cerevisiae)
MIER1 mesoderm induction early response 1, transcriptional regulator
MINK1 misshapen-like kinase 1
MTFR2 mitochondrial fission regulator 2
MYOZ2 myozenin 2
NAV2 neuron navigator 2
NCEH1 neutral cholesterol ester hydrolase 1
NCOA7 nuclear receptor coactivator 7
NCS1 neuronal calcium sensor 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NMRAL1 NmrA-like family domain containing 1
NOTCH2 notch 2
NPHP4 nephronophthisis 4
NRROS negative regulator of reactive oxygen species
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUP155 nucleoporin 155kDa
NXPE3 neurexophilin and PC-esterase domain family, member 3
OAF OAF homolog (Drosophila)
OCA2 oculocutaneous albinism II
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAK1IP1 PAK1 interacting protein 1
PANK1 pantothenate kinase 1
PARP10 poly (ADP-ribose) polymerase family, member 10
PARP14 poly (ADP-ribose) polymerase family, member 14
PCM1 pericentriolar material 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD11 programmed cell death 11
PDLIM1 PDZ and LIM domain 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGBD2 piggyBac transposable element derived 2
PHF3 PHD finger protein 3
PKN3 protein kinase N3
PLSCR3 phospholipid scramblase 3
PLXDC2 plexin domain containing 2
PLXND1 plexin D1
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PRDM2 PR domain containing 2, with ZNF domain
PRDM4 PR domain containing 4
PRRC2B proline-rich coiled-coil 2B
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RELL1 RELT-like 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPA1 replication protein A1, 70kDa
RPS10-NUDT3 RPS10-NUDT3 readthrough
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SAFB scaffold attachment factor B
SAMD9 sterile alpha motif domain containing 9
SBF2 SET binding factor 2
SEC24D SEC24 family member D
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SENP5 SUMO1/sentrin specific peptidase 5
SEPT2 septin 2
SH3BP1 SH3-domain binding protein 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLFN5 schlafen family member 5
SLIT2 slit homolog 2 (Drosophila)
SMAP1 small ArfGAP 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SNRK SNF related kinase
SRRM2 serine/arginine repetitive matrix 2
SUCO SUN domain containing ossification factor
TDP2 tyrosyl-DNA phosphodiesterase 2
TENM3 teneurin transmembrane protein 3
TMCO1 transmembrane and coiled-coil domains 1
TMEM39B transmembrane protein 39B
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TP53BP1 tumor protein p53 binding protein 1
TRIM39 tripartite motif containing 39
TRIM39-RPP21 TRIM39-RPP21 readthrough
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae)
TRMT5 tRNA methyltransferase 5
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPS1 trichorhinophalangeal syndrome I
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TTC7B tetratricopeptide repeat domain 7B
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
UBAP2L ubiquitin associated protein 2-like
UBTF upstream binding transcription factor, RNA polymerase I
USP37 ubiquitin specific peptidase 37
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VCL vinculin
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR13 WD repeat domain 13
ZCCHC3 zinc finger, CCHC domain containing 3
ZDHHC21 zinc finger, DHHC-type containing 21
ZEB2 zinc finger E-box binding homeobox 2
ZNF23 zinc finger protein 23
ZNF326 zinc finger protein 326
ZNF490 zinc finger protein 490
ZNF592 zinc finger protein 592
ZNF787 zinc finger protein 787
ZNF883 zinc finger protein 883
ZSCAN20 zinc finger and SCAN domain containing 20
ZXDB zinc finger, X-linked, duplicated B
ZYG11B zyg-11 family member B, cell cycle regulator