|Dataset||GO Molecular Function Annotations|
|Category||structural or functional annotations|
|Description||Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA. (Gene Ontology, GO_0035539)|
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2 genes performing the 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.